Can I still blast test if my most recent TRT labs show consistent high e2?

Just to preface, I don’t have high e2 symptoms hardly ever. Sometimes slight ED. And everything else on labs are perfect

Was hoping to blast to 500mg/week test if my recent labs (Monday) came back good. Everything was great except for my e2 (74ng / 275 nmol) my e2 has been high for the last 5 months or so, last lab showed 240 3 months ago. No matter what I do with my protocol it never seems to go down. I don’t have high e2 symptoms aside from slightly weak hardons every now and then. But I take 5mg cialis EOD so can’t say I’ve noticed much of that

Am I good to go as long as I don’t see symptoms of high e2? I have arimidex on hand if I start seeing symptoms but honestly doesn’t seem like arimidex does anything for me based on my last 2 labs

My TRT is

Split twice a week

120 test e
1mg adex
500HCG (dropped from 1000 in the last 3 months to see if my e2 would go down, but it just went up)

Most recent labs were

Total T 690
SHBG 27
E2 275 (74ng)

My labs were drawn 4 days exactly following my 60mg injection / .5adex / 250iuhcg

Thanks

I’m just not seeing a problem here, only an opportunity to create one.

Arimidex can’t lower E2 produced inside the testicles from the hCG use.

There can be numerous reasons why this is the case. HCG can be the cause fluid retention or fluid imbalance within the body.

Estrogen can influence serotonin, so excess serotonin from elevated estrogen can have the same effect an antidepressant can have on your erections.

@systemlord Thanks for the response.

“I am not seeing a problem here, only an opportunity to create one”

Would you be able to elaborate on that? Appreciate your time

Arimidex is a powerful drug and you may trade high estrogen for crashed estrogen.

I once took 0.050 anastrozole and estrogen went to zero from a level of 90 pg/mL!

@systemlord I’ve been taking 1mg / week every week for 6 years because my doc has told me to. I’ve never had an e2 reading below 100pmol or come even close to crashing. I’d love to stop using it but if my e2 is already high while using it I’m afraid to remove it.

I would be more afraid to take an AI, because it can alter your lipids and remove mineral from bone. Taking an AI because your doctor told you to isn’t a good enough reason to take it.

Always assume your doctor doesn’t know what the f*** he’s talking about, because they’re only human. Majority of doctors are taught what the pharmaceutical companies want them to know and not what they don’t want them to know.

An example, statins are inferior to dietary, lifestyle changes.

@systemlord how would you recommend I remove it from my protocol? I feel that if I removed it entirely I will def rapidly see e2 sides considering I’m already at 275 while taking it. Especially if my goal is to blast test. Should I taper off?

I don’t disagree with you but I’m having a hard time understanding why coming off of it and having my e2 absolutely skyrocket is a better solution. I’m not educated enough in this area and have been trying to wrap my head around it for weeks

Where did you learn high estrogen was bad for you?

You could taper and assess how you feel on the way down.

My estrogen is high on TRT. I want it high as it increases my muscle mass, lowers fat mass and makes me more sensitive to insulin. It’s great for sexual function too.

@systemlord i am reading mixed reviews everywhere on multiple forums.

Some say go based on symptoms if the numbers are high and you feel fine you’re good.

Others say elevated levels of e2 long term can be detrimental to your health.

No real elaboration on these statements or studies to back them. But opinions seem to be all over the place

Many of the studies on estrogen are seriously flawed! An imbalance of these two hormones are detrimental to your health. In other words, a male with low testosterone and high estrogen is bad for your health, but high testosterone and high estrogen are not bad for you.

Welcome to the world of sex hormones, where the majority of people doesn’t know what they’re talking about. Comparing a low testosterone, high estrogen male to one with high levels of both is hardly a fair comparison.

Okay thank you. @systemlord

Would you consider 690 total test and 75 e2 a healthy range long term? Potentially higher e2 if AI is removed?

Also. Any suggestions on weather or not I’m good to blast without having to worry about my e2 running high or recommendations to approach?

Again really appreciate you taking the time to chat this out with me

The normal ranges for estrogen (20-40 pg/mL) we derived for men not on TRT, and with a Total T <500 ng/dL.

In recent studies, low E2 has been associated with low bone density, higher fat mass, worse lipids, and lower libido in men. Anecdotally, men complain of low penile sensitivity with low E2.

Many men on TRT associate water retention with high E2 and ignore the increased TRT-related sodium retention as a cause.

0.3-0.4% of T aromatizes to E2. Those ratios look fine to me.

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