Broken Brain Syndrome: Why is Everyone Messed Up Today?

Chris Shugart

Omega-3 Deficiency

This common nutritional deficiency makes you tired, sad, and anxious. Left unchecked, it can lead to severe cognitive impairment. Let's prevent that.

Way, way back in human history, one of your ancestors did something that changed the future: he moved to the coast and discovered that the ocean is full of food. Catching fish was easier than chasing land critters. That's all he knew. What he didn't know was that he was setting something into motion that changed the course of history: brain expansion.

It's called the Aquatic Ape Hypothesis. It may or may not be correct, but the general idea makes sense: This new food source was rich in DHA (Buy at Amazon), one of the most important omega-3 fatty acids, along with EPA. Your body can't make these essential fats; you have to eat them, and DHA is literally brain food.

Your ancestor got a little DHA from other sources, and he converted ALA from plants into DHA/EPA. Unfortunately, the conversion rate is terrible (2 to 5%), especially for males. But migrating to the coast changed all that. Now your ancestor's brain was saturated in DHA. As the generations came and went, human brain development went into hyperdrive. Cognitive function skyrocketed. Mankind flourished and today we have pocket computers and spaceships.

It's a good story, but it's not over. These days, despite all our advancements, we're at risk of cognitive "de-evolution." Our brain machinery is dry and rusty: it's overheated, misfiring, and sending mixed signals.

It sounds melodramatic, but medicine has a new term for it: omega-3 deficiency.

Omega-3 Deficiency: What Does It Do to Me?

Lack of omega-3s, particularly DHA, cause or exacerbate several brain-related issues:

  • Mood Problems: Increased anxiety, more depression, and mood swings. Omega-3s are involved in neurotransmitter regulation (serotonin and dopamine), critical for mood stability. Without omega-3s, the brain gets inflamed, leading to depressive symptoms and anxiety.
  • Fatigue: Lack of energy or a feeling of generalized tiredness.
  • Poor Memory: Difficulty concentrating or recalling information.
  • Very Bad Things: At the extreme end, but not uncommon, omega-3 deficiency is associated with ADHD, bipolar disorder, schizophrenia, and dementia (including early-onset Alzheimer's, affecting people between 30 and 50).

In short, a lack of "brain food" is causing rampant cognitive impairment, general unhappiness, and what could be deemed a diet-related form of stupidity.

How Can I Avoid or Correct Omega-3 Deficiency?

According to the literature, moderate to severe deficiencies require a consistent intake of just over 1000 mg per day (about half that works for a mild deficiency).

However, more focused research on things like depression and mood points to a much higher intake. You'd need to consume a whole lot of salmon and mackerel daily to get enough. And then you'd need to start worrying about heavy metal contamination and microplastics.

Supplements are the smart choice, but the average grocery-store fish oil contains roughly 360 mg of combined DHA/EPA per capsule. Sadly, most of that is EPA, and the powerhouse brain food is DHA. Prepare to swallow a lot of capsules.

Or, take a concentrated, self-emulsifying supplement. A single softgel of Flameout DHA-Rich Fish Oil (Buy at Amazon) contains 667 mg of DHA (plus 133 mg of EPA). Just two capsules daily corrects even a severe omega-3 deficiency. Your brain will be happy.

Buy Flameout at Amazon

Reference

  1. Kruger et al. "Incidence and Prevalence of Early-Onset Dementia in Finland." Neurology. July 24, 2024, issue 104.
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It seems that DHA is a potent supplement for brain health, but EPA seems to have stronger effects on cardiovascular health. (The prescription drug Vascepa, used for those with high trigylercides, is pure EPA).

Do we really know enough to start altering the ratio, if the objective is overall health? What is the optimal DHA/EPA ratio for overall health benefits?

Given that mega doses of Omega-3 are sometimes associated with an increased risk of A-fib, do we know much about the independent effects of the DHA vs EPA on this potential adverse effect?

Dr. Chris Palmer wrote a book, Brain Energy" (ASIN B09SKPDT36). In it, he states that all long term mental illness including addiction is mitochondrial disfunction. The vast majority of people who eat keto or carnivore say that their mental health improved. From less mild depression or anxiety to complete removal of clinical depression and addictions.

Keto cured my type 2 bipolar (treatment resistant) and my excessive drinking and Iā€™m down 83 pounds from my worst. The change in energy levels was noticeable in just two days. The depression disappeared slower, I noticed it in maybe two to three weeks. Now on carnivore, my chronic back pain is gone. Iā€™ve yet to regain my former muscle mass. Maybe without the chronic back pain I can heal and then not reinjure myself deadlifting more than 185 again.

For millions of years, humans were in ketosis all the time. In that state, about one third of the brain runs on glucose and the other to thirds run on ketones. Like the majority of mammals, our default state is ketosis and our brains function better that way.

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