Bloodwork Over the Years, TRT On and Off


TRT1 between 25/11/2012 till 09/2014
TRT 2 between 29/2/2015 till 30/4/2015
Since march 2016 till now on TRT 3 :250mg undecanoate every two weeks
Kickstart every TRT was 1000 mg, 500, 500, 500, then followed by 250mg every two weeks

  1. anybody knows why pancreatic values are allways elevated? I consume a lot of fast sugars, is that a possible explanation? Pancreas has to do more work than normal?
    2)TSH value rises above 2 and 3 when on TRT, when I’m off it drops below 2. What is the scientific reason herefore?
    3)SHBG values allways elevated, even when I’m off TRT

any other thoughts/inputs are also welcome

Ck values two times off the charts trough rhabdomyolysis (ultraruns)
Ref values at the right
Speaking Dutch…

I’ve noticed the same thing myself. I was below 2 pre-TRT and now I’m usually above 3 on TRT.

I believe SHBG is largely genetic. It just means you need more testosterone than most to feel optimal while on TRT. Although I have not seen levels this high on someone.

these are the numbers 2011-2012. The end of 2011 I stopped cycling T (very high value of Total T in 06/11 and low SHBG–> lots of free T).
9 months after I dropped all androgens still very low free T due the high SHBG–> decision to go on TRT as in starting topic

Metabolic demand is greater on TRT, TRT increases metabolic rates and the thyroid gland must step it up to meet this higher demand. A TSH above 3.0 is no good, it’s a sign your thyroid is starting to struggle.

My TSH didn’t move that much after starting TRT, 0.6->1.01. As for the elevated SHBG on TRT, undecanoate has a long acting ester and you need a short acting ester to hit your system with a lot of androgens to suppress SHBG.

You need a flood of androgens in order to decrease SHBG, not a long gradual release of androgens. It doesn’t matter how often you inject because that half-life is too long.

Ah, so this isn’t a coincidence. Will likely tackle Thyroid after I get settled with my dailies protocol then.

Testosterone is metabolized in the liver, thyroid hormone is needed for this process to occur. Men trying to dial in their TRT protocol when their thyroid is not functioning optimally, good luck with that.

TRT cannot work well when there are thyroid problems. You really need to check thyroid hormones to get a better ideal how the thyroid is performing. TSH is a stimulating hormone, fT3 is the main active thyroid hormone and rT3 can block fT3 at receptor sites.

@systemlord Hmm, currently switched from biweekly testosterone protocol to strictly T Cyp dailies. So far, I feel on average better than I did before (often great) and currently letting it sync into my system for the next few weeks and will get bloodwork to verify the results.

Would you get a doc consultation regarding the thyroid immediately or at some other time? Since I already got bloodwork a few weeks ago, I could just go by that. My doc already said he is open to exploring this option, especially if my estrogen is under control.

Contunously elevated lipase levels can be a sign of chronic pancreatitis, you definitly wanna be careful with that.
Did you get your pancreas/liver/gallbladder checked by ultrasound for signs of gallstones or a dilated pancreatic duct or the presence of pseudocysts?
Even more sensitive would be a Magnetic resonance cholangiopancreatography (MRCP).

Go and see a physician specialized in gastroenterology.

no never done specific pancreatic tests.
The several bloodworks over the years were done by several normal doctors, not once was there a doctor who was concerned over the parncreatic values cause they were minor elevations…But when I asked an explanation, none of them could give an answer.

Have seen a specialist in gastorenterology in the past year cause I suffered from my intestines. She found nothing more then a lactose intolerance but she only investigated the intestines.

I guess that’s different lipase tests over the time, right? Some are higher as others and they have different reference ranges?

Everything higher than 3 times the upper ref range is classified as acute pancreatitis. I guess for some values that’s close to that. Chronic minor elevations are typically seen in chronic pancreatitis.

That’s something you really wanna take serious, 100 times more important than T.

diff reference ranges due to the different labs
Lipase and amylase minor elevations were indeed tests over a time (past 11 years) and the were always elevated (1 to 2 times highest reference values).

I believe you have subclinical hypothyroidism.

Do you possibly have any other thyroid values like FT3, FT4, RT3?

FT4 is mentioned in the stats, it’s called vrij T4 (vrij=free)

No FT3 or RT3 tested in the past 11 years
Will aks it in a next labtest

Subclinical= latent?

I would wait 8 weeks and access things from there, once levels are stable, then retest thyroid.

Oh got it.

Well, that is a really shitty FT4 values so you clearly have hypothyroidism.

Just TSH or go ahead with T3, T4, rT3?

It’s better to do all because you only get more detailed info testing everything. TSH by itself is almost useless, it would like testing a guys natural T status but only testing LH.

Will do. How off the optimal range for the thyroid levels would you consider a medication like T3/Cytomel? I’m going off the Dr. Westin Childs article you referred to me earlier.

According to the chart, I’ve never been close to optimal TSH and at my best (2.07 TSH), my Reverse T3 was 21.3. Never checked total T4 or antibodies.