Bloodwork: Low Test, Low Estrogen

Anybody? @KSman? I’m in a holding pattern waiting for my new insurance info to come in. The endo is going to run some more blood work first so we know what’s going on. I’m fairly certain my estrogen is crashed again. I’m constantly urinating. Sat in a sauna at the gym and could barely break a sweat. I currently can achieve an erection but with very limited sensitivity. My joints are killing me. I just want to feel normal.

Unless I am missing something, given what you’ve posted so far, I would get on some test, anastrozole and maybe DHEA (don’t recall they checked that). Get your dosages worked out, may take a little bit of time.

As for enanthate, I’ve used both it and cypionate, currently taking enanthate. I do not feel any difference with either ester. I also do once weekly injections and feel just fine with those. If I skip an injection, I don’t really notice anything until towards the end of the second week.

Thanks @highpull, I’m going to do one more set of bloodwork and talk with the endo. See what she recommends and how my blood work may have changed since my botched up vasectomy. I’m ready to take some action on this and take control of my health. Based on my low shbg do you think Clomid alone might help? I have a bunch of Clomid but I’ve never taken any…

Not a big fan of clomid, but it works for some (secondary). You could try it, given your LH/FSH numbers. I think you’ll end up on TRT eventually.

@highpull, I believe you are right and I’m not opposed to it anymore. I’m just looking for some relief. I lost my doctor due to an insurance change. I’m now going to see this endo but I don’t think she knows what she is talking about. Per the stickies I contacted compounding pharmacies looking for referral and came up with Jack shit. Asked my neighbor who I know is on 200 mg a week cypionate but his doc won’t prescribe AI. To me that’s a red flag and a recipe for disaster.

Doctors who refuse to prescribe AI’s are behind the times and likely will not prescribe HCG. They believe TRT is about prescribing testosterone and calling it a day, these type likely won’t bother checking E2 levels. It’s as if they’ll meet you half way with regards to TRT and too bad if you end up converting to much of your T to E2.

@systemlord, my neighbors doc put him on 200 mg a week with NO AI! He felt so bad he dropped the cypionate cold turkey and walked away. I feel sorry for him. I hope I have enough knowledge to not end up like him. I believe I do. I just want a good doctor. Has anyone heard of Titan Mens Health? They are in League City Texas…

Slight Update:
My urologist prescribed me Cialis Daily 5mg. Insurance will only allow me 6 pills every 30 days so I picked the 6 up yesterday. Took half of one pill so 2.5mg at 10am. About 45 minutes later my pecker started to tingle. No erection but it was obvious it had more blood in it. I got a little light headed. Kinda like head in a bubble type feeling. Warm sensation in my face. That lasted about 4 hours then I was hit by a tiredness I have never felt before. Fought to keep my eyes open for at least a half hour and finally gave up. Took a nap at 2pm. Slept really really hard for 30 minutes. Woke up with a puddle of drool on the pillow. Not sure if that’s normal or if my blood pressure dropped to low because of the meds. Had a great back and bi’s workout this morning. Good blood pump. I’m not gonna take it that early anymore. Maybe 6 or 7 o’clock next time. Anyone else have any experiences like this?

Bump

You have low testosterone, and symptoms consistent with such, and your doctor gives you Cialis? You are not taking testosterone?

I am not currently taking testosterone. I’m open to it at this point. I’m waiting on blood test to come back right now. Based on these results I will be taking action. Either trt or restart. Not sure which yet. If the endo says trt than trt. If she denies me trt I’m gonna do a restart myself. I have everything I need to do testosterone or a restart solo. I just don’t plan on living 2018 like 2016 & 2017.

Just heard from the Endo… they didnt give me all the results yet but the nurse in the phone said my Estradiol is 12.1 (7.6-42.6). Looks like I am crashed again. It’s not as bad as before (<5). It gives me a pretty good idea where my Test levels are. Waiting for a call back now.

Are you certain that’s the correct E2 test? The ranges look like the female hormone range and if so your E2 is even lower than reported.

@systemlord, I have no idea at this point. I keep asking for sensitive but keep getting the same results.

It’s the Roche ECLIA methodology @systemlord

This estradiol assay is designed for the investigation of fertility of women of reproductive age and for the support of in vitro fertilization. You require Estradiol, Sensitive, LC/MS. Whoever ordered this test for you has no clue and isn’t skilled enough to balance your hormones if they do not understand that this is the wrong test.

Limitations
E2 levels in children, postmenopausal women, and men are much lower than in women of reproductive age. The increased sensitivity and specificity that are achieved by LC/MS-MS are the more appropriate choice for these clinical situations than the electrochemiluminescence immunoassay (ECLIA) method.1,2 See Estradiol, Sensitive, LC/MS [140244]. LC/MS-MS offers superior analytical sensitivity, specificity and a larger dynamic range than immunoassays.1 The clinical applications benefiting from highly sensitive E2 measurement include the assessment of congenital defects in sex steroid metabolism and disorders of puberty. This sensitive assay also has application in the evaluation of estrogen deficiency in men and menopausal women, fracture risk assessment in these populations, and increasingly, in therapeutic drug monitoring of low-dose female hormone replacement therapy or antiestrogen treatment.

So it’s safe to say at this point that 12.1 is overstating estradiol and that I’m most likely even lower than that. Geez. I can’t wait to see what my Test levels are.

When my test levels were measured (119 ng/dL) estradiol was undetectable even on the ECLIA method. Your E2 is converted from your FT and since your E2 is low FT is also expected to be quite low. TT by itself means nothing since FT is the active hormone. We use SHBG together with TT to determine our FT, direct measurement isn’t accurate.

I know my Test is low. Hopefully this Endo will take action and stop stringing me along. She gave the nurses specific instructions not to release my results. She wants me to wait until her appointment on the 29th before I can see them. The nurse was kind enough to tell me the estradiol results on the phone. What a mess I’m in…

Sitting in the waiting room now to go over the blood test results with the endo. I’ll be posting them shortly.