Bloods After 4 Weeks TRT

Pharma TRT
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Hi everyone! I’m 39yo 5’10" 163lbs 8-12 body fat. I high school I used Androstenedione and Tribulus Terrestris. I suffered from “chronic fatigue” after coming off, not realizing I just did steroids for a long time. Did 1 testosterone cycle at 24, another at 30, then at 37 I ran an 8 month cycle at 200mg…I felt so good I didn’t want to come off

At 38 I suffered a back injury, got a major infection during surgery and was on PICC line antibiotics for 12 weeks, and opiates for a few months. I had just got done with PCT the day before the surgery…my immune system just wasn’t ready.

I had been feeling like garbage, couldn’t sleep, depressed, anxiety…felt horrible. 2 months ago I decided to get my Total Testosterone and Free Testosterone checked:

Total T- 390 ng/dl
Free T- 6.8

My 2nd test 3 weeks later were:
Total T- 420ng/dl
Free T- 4.2

I decided to go TRT as my doctor would not help me, and she wanted me to see an Endo which would not help me because my total T fell in the normal range over 290 ng/dl). For the past 4 weeks I’ve been injecting Testosterone Enanthate about 50mg every 3.5 days…Soo 100mg per week. I did blood work last week through LetsGetChecked…the following were my results:

Total T- 1239 ng/dl (259-1041 ng/dl) HIGH
Free Testosterone- 29 (4.7-24.4 ng/dl) HIGH
Free Androgen Index- 105.39 (31-102 ng/dl) H
Estradiol- 42 (8-39 pg/ml) HIGH
Prolactin- 16.6 (4-15.2 ng/dl) HIGH
SHBG- 42 (17-53.6 nmol/l)

I am currently taking Boron 6mg once a day (which probably lowered my SHBG-).

My diet is VERY clean. I feel great, better than I have in well over a year given what I’ve been through, and my sleep is ok…6 hours to 7 hours+…hard to stay asleep at times. I do wake up a few times a night. I did notice my fasted blood sugar has trouble going below 95 in the morning and throughout the day. Blood sugar does come down after meals. Blood pressure is perfect, and has actually gotten lower since I started TRT and working out again.

Now remember…over the last year, April 13, 2021 to about October 2021 I was spending 95% time in a hospital bed. I just started working out again about 2 months ago now after my spinal fusion on January 18, 2022.

My question…should I be worried? I feel great. My sex drive is through the roof. My penis works just fine. I wake up with morning wood…I wasn’t before TRT this year. I’m energized, feel like living and working.

I’m thinking about lowering my dose to 35mg or so every 3.5 days. Would this lower my Estradiol and Prolactin naturally? I don’t want to take any AI’s as I do not have estrogenic side effects.

Any thoughts are appreciated. Thanks guys! Stay swole!

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No, you should not.

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Wait a bit longer (6-8 week range from starting TRT) and get bloods then. You’ll probably see that your TT lowers a bit from the results you just got because youre body is likely still mid-shutdown… this means you will probably have some remaining natural production in addition to your exogenous test reaction.
I also wouldn’t reduce your dose yet, you need 6-8 weeks minimum on almost any protocol before fully assessing ‘feel’ and whatnot.

As @highpull said, you should not be worried. If this dose makes you feel good, I certainly wouldn’t change it unless significant other concerns arise.

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[sarcasm]Your total T and free T are above range. You are in supraphysiological range, and are doing a steroid cycle. You must stop immediately or certain graphs will explode![/sarcasm]

Seriously, if you feel good, I think you should continue.

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As long as other biomarkers are healthy (CBC), these levels are safe. I wouldn’t be surprised if your levels were higher in two more weeks.

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I am glad you are feeling better man. I hope the anabolic/treatment effects continue to provide you relief. If you find the sleep issues bothersome longer term you could consider reducing your dosing somewhat as you have mentioned. Congrats!

These results are at trough before next injection?

Reassess how you are feeling at 12 weeks and 6 months so you give it time for changes to manifest.

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Actually no. It’s just another data point on the graph. The graphs don’t judge. But they do inform.

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Personally I’d welcome a crowdsourced method to collect data for graphs like the two above. Would be helpful to inform on topics like this:

Hilarious how I get mocked for collecting and analyzing these data:
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You’re welcome. One more graph for you:

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Thank you…my head is spinning looking at the graphs lol. I’m trying to figure out where I lye and can see dots, lines, and pretty colors lol

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Thank you I appreciate it! I pin Monday and Thursday so I took these bloods Thursday morning. I did it in the middle bc I was curious what the numbers looked like in the middle of the week in between pins. I should do the trough on Monday morning correct? Do you think that mattered?

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CBC was normal for the first time in over a year so I thought that was a great sign!

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Ok great…thank you for the advice I really appreciate it. I did just pick some P5P up to try and lower the Prolactin. Wouldn’t hurt…right?

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Before you next injection or after?

Trough would be before your next injection in the sequence.

I’m not getting something. Maybe you meant Tuesday instead of Thursday for blood draw? But regardless if you took the blood halfway between injections that should give you a decent idea of mean level.

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I can’t definitively say either way. Right now your numbers are in limbo so I would personally wait for the 6-8 week mark before adding new compounds.

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I took the bloods Thursday morning before 2nd injection of the week as I pin Monday and Thursday. I figure Monday morning before injection is the trough being that Fri, Sat, Sun is 3 full days between pinning and is the longest break. Correct?

Sorry for the confusion, and your help is appreciated

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Gotcha, thanks for clarifying. Yes, 3 day trough vs full 4 day trough. Using 4.5 day half life, an extra day is worth an additional 14% loss on your TT measurement.

0.5^(1/4.5) = 0.857

Hence, 1239*(0.857) = 1062.

So trough on Monday should read a little above 1000 ng/dl.

Your mean TT would be close to ~1400 ng/dl. That’s an excellent response to 100 mg/wk TC.

Mean TT = 1.21 * trough(E3.5D) = 1.21*1150 = 1392 ng/dl

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Wow thank you so much for explaining it like this. So essentially I should be right where I need to be? I’m just praying that I my estrogen and Prolactin being so high doesn’t mess with me. I will take new bloods in 4 weeks and update here. With my CBC being in check I don’t see why I would change anything, although I also need to run a CMP to make sure the kidneys are ok.

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That depends on lipids, BP, CBC, CMP, etc. The higher PRL would be a problem for me, but not everyone. If your other health markers are fine then you are fine. If they are not, then I’d lower your dose