Benefits of Estrogen for TRT Patients

Thanks for sharing. no matter what the studies say it’s showing that many men are off ai and have zero problems after fearing estrogen.

All we gotta do is peak at a few posts of long timers and see how they benefitted.

Oh got it. Never heard of it. It is created from Pregnalone so I’m surprised how it would reduce others after the fact. Anyways let me know if you find more info. I wouldn’t worry about it since you are on trt.

A new article on men , hormones, health and age:

When they adjusted for factors such as age and cardiovascular disease, they found that estradiol was linked with telomere length. The higher the estradiol, the longer the telomeres, and thus the lower the biological age.

https://www.endocrineweb.com/news/other-endocrine-disorders/61835-want-lower-your-biological-age-androgen-levels-offer-clue

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Yh but, if you want that ripped dried and grainy look, you gotta nuke all dat estrogen bruh. Cant be carrying water

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Right :slight_smile:

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There definitely is a place for not using and using an AI.

Obese? Use AI. Roidmonster with lots of aromatazing juice? Use AI unless you want that gyno surgery. An obese roidmonster using aromatazing roids? ABSOLUTELY use the AI.

Now the hard part. There is a sweet spot for E2 for all, but how will you find it when even the top docs in TRT field dont agree on it? Some swear by the “20 to 30 range”, some swear on T to E2 ratio.

Who is right and who is wrong? Learning your body and going by symptoms? Managing E2 is eternal OCD hell for micromanagers!

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It seems like guys with high SHGB can tolerate more Free E2 in their blood or more than likely their high SHGB is binding up all that excess E2. Which renders it harmless.

Guys like myself with a mid level SHGB (24-29 over the last 6 years) or lower are not as lucky. Too much Free E2 is a major bummer and time will not fix it. You drop your T dose or take micro doses of anastrozole. I have not discovered any other options.

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I actually think spreading out the dose is better.

When I moved to eod, my e2 rose quite a bit. At e3d it was lower.

I think more of a gap between doses gives your body the time to clear out estrogens. Jamming it eod with test seems to clog things up e2 wise. Make sense? Just my thoughts on it.

Granted it all depends on how much your dosing on each protocol.

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Interesting. I wonder if e2 clearing is also affecting by subq which is why ppl switch to subq to lower e2. It did not lower for me. It was a bit lower on I’M actually. Maybe like you said it clears faster on im though it may peak higher because On subq it’s a slow release that is constantly making e2???

Am sure it’s more complicated.

What’s the longest you’ve gone without managing e2? Like letting it rise with free t naturally. We’re finding that most men just need a big more free t to balance out the estrogen.

If guys don’t do daily they should. Otherwise the estrogen is spiking and causing symptoms.

The serum tests for estrogen are not painting the full picture. We’re finding that estrogen is created and works in specific areas like the Brian, heart, testicles and bones. The blood test does not pick up on this.

I wonder if it was an inaccurate test. It’s odd to see a lower result. Did you test the day after or ?

Something is up with enackers, he keeps repeating shit cuz he seen a coup of vids and is now enlightened.

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The more frequent you dose your T the less trough you will have. This alone will raise your E2 hell it will raise your average TT lvl as well. If you want your TT to remain the same you have to reduce the week dose when injecting more frequently. There is no rule but I have read several guys who were on weekly and went to daily had to reduce their week dose by 20%. disclaimer: I have not done this test and backed it up with bloods. I am only repeating what I have read from TRT guys I trust.

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It would be interesting to take a couple hundred guys on various doses and injection schedules and have their blood drawn every day for a week.

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@hrdlvn,

Is that right? E2 goes up when dosing more frequently?

I had assumed the opposite because there is less of a spike, and so less aromatization. But that was only an assumption on my part…I had been contemplating trying out daily…but if E2 goes up, then forget it.

I’ve also read studies suggesting the opposite. More frequent administration should cause less increase in E2, less increase in hematocrit and less side effects.

When I start TRT I start it ED right of the start, not experimenting 2 times a week or even EOD stuff with my extreme sensitivity I will sense all peaks and dips for sure

You should generally decrease dosage when increasing frequency, which SHOULD reduce e2.

I saw a higher rise in e2 when I increased frequency from E3d to Eod. However, from Eod to daily, e2 dropped dramatically.

It’s all subjective.

Wont bigger doses also create a larger spike in DHT which function to decrease e2?

This is all good info, but we all have to also remember that EVERYTHING concerning TRT is subjective, and we are ALL individuals. High levels of E2 have nothing but good beneficial effects for some (well, ALL scientifically speaking, but for some the side effects at first are just too great)…others go through hell higher than level X. Same on the lower side. And guess what? These specific numbers WILL CHANGE over time, especially as your body composition changes.

It’s easy for some guys to say just let it ride. E2 is GOOD for you. Again, scientifically speaking, they aren’t wrong, but tell that to the guy who is dialing in his protocol, and his Free T is still at 13, and his E2 has crept up to 57! You will have a hard time convincing him that high E2 is good for him because he will feel like his wife just before her period, or worse! ****No offense to the females here…I sincerely feel for you and applaud you guys for having to deal with that shit every month, and still staying sane!! ***

Everyone here is correct in their own right. Bottom line is that you have to play with things to find out what effects you how over time, then stick with what gives you the greatest benefits without any side effects for as long as you can. Once you do that…You’re going to wake up a few years later and realize that something isn’t quite right, and have to tweak things again.

Bottom bottom line is this…Push your test as high as you can without adverse consequences (high HCT, enlarged heart (which is only a concern for people that cycle often typically), excess aromatization of E2, etc…), and let E2 naturally go as high as it wants without adverse consequences (mood shifts, limp dick, breast enlargement, gland development (in conjunction with elevated prolactin). Test levels should be treated as a proactive regimen (actively pushing and then stabilizing, then repeat until you hit the limit). E2 levels should be reactive (leave them alone until you stabilize, then see if you have a reason to not leave those levels alone). Even then, you should try controlling those levels by adjusting the Test dosage (minimizing the aromatase effect), unless your Test levels are still insanely low.

What winds up being your sweet spot will almost assuredly be different than EVERYONE else here.

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This will depend of the individuals rate of conversion of both estrogen and DHT.