Androgen/Estrogen Receptor Effects

I’m creating this topic because I think it will be good to everybody here and I think some expert people may also help.

I saw a lot of guys with very high e2 some with good testosterone and others with low testosterone. Do you guys know why they don’t get gynecomastia?

Other guy I know had high e2 and when he took tribulus terrestris he got puffy nipples but not before. I really want to understand that because it seems that some people don’t feel their hormones but when they can “activate” it they can feel the bad sides like gynecomastia or the good sides like libido, energy etc. Do you guys know anything about it? I’m really interest to know more about it to solve my problems and some friends that are facing the same thing.

Some guys are susceptible to gynecomastia, some aren’t.

But the elevetaed estrogen levels we usually discuss are slightly above range, which wont cause gyno issues for most unless they already have gyno present.

Most guys would only get it on cycle with uncontrolled high estradiol levels, or from puberty, not TRT levels.

What do you mean by “activating” ones hormones.

I mean I saw a guy that had high E2 with no libido, ED etc. When he had lower E2 and he took tribulus he got good libido and no ED. But when he took tribulus with the high E2 he had the puffy nipple thing.

Maybe tribulus activate the androgen and or the estrogen receptor. That’s why the people get libido from it or can get the bad effects like gynecomastia.

Other guy with high E2 didn’t feel the gynecomastia, when he took masteron he started to feel the prostate aching and the gynecomastia.

Was that really masteron or some impostor or fake?

Can’t really do much with an uncontrolled experiments with populations of one. We had some herbal products here that had prohormones in them. So with reports like yours that do not make sense, the “drug” can be the the problem and one suspects that is might not be real.

Really masteron. The guy started to feel his prostate aching, his was relating in a lot of forums even in propeciahelp because he took propecia and received the side effects.

I think there is something that activate our receptors or maybe androgens that bind to the androgen receptors create the prostate and puffy nipples problems when E2 is too high. Because we can see even here guys with high E2 not feeling any issue from it beside low libido, ED. So there is something that makes the high e2 bad.