subq absorbs slower and your hormone levels are then steadier avoiding peaks and troughs.
High peaks from infrequent injections can really mess with your mood/mind and can also promote high hematocrit and higher estradiol [E2] levels.
Most need to actively manage E2 levels with anastrozole to get near E2=22pg/ml - 80 pmol/L. Anastrozole is a competitive drug and needs to be matched to your serum T levels. So if serum T levels are not steady, E2 management will not be good.
All T injected subq or IM is100% absorbed.
subq also avoids a lifetime of muscle damage
insulin needles are all that you need for subq or shallow IM.
Suggest #29 1/2" 0.5ml [not 1.0ml] insulin syringes.
Pinch up skin over upper leg and inject into end of fold with needle parallel to and avoiding muscles. Look for and avoid veins.
After injecting, press firmly on injection site with finger to allow tissues to seal up avoiding leakage or bleed bruising.
Please read the stickies found here: About the T Replacement Category - #2 by KSman
- advice for new guys - need more info about you
- things that damage your hormones
- protocol for injections
- finding a TRT doc
Evaluate your overall thyroid function by checking oral body temperatures as per the thyroid basics sticky. Thyroid hormone fT3 is what gets the job done and it regulates mitochondrial activity, the source of ATP which is the universal currency of cellular energy. This is part of the body’s temperature control loop. This can get messed up if you are iodine deficient. In many countries, you need to be using iodized salt. Other countries add iodine to dairy or bread.