Academic Review of Modafinil

[quote]dantheman wrote:
First, it does say steroids and only steroids now.

[/quote]

I’m very sorry but you’re wrong dude. It says clearly “Steroids and other drugs”.

Have a nice day…

funmetal

Schwartz, got any info on L-Dopa substances ? I hear sprinters are loving it, and its undetected, not to mention very cheap.

[quote]JasonR wrote:
Schwartz, got any info on L-Dopa substances ? I hear sprinters are loving it, and its undetected, not to mention very cheap.[/quote]

I’d imagine it’s popular because dopamine enhances motor learning and neural plasticity associated with repeated tasks. Basically it helps learning technique and motor patterns faster. Is this why it’s popular, or for another reason?

Dan-
As a suggestion I wouldn’t bash steroids in the steroid forum. (more or less what you did by saying you didn’t want it associated with AAS)

Anyway though I saw that it could be used for ADD, do you guys think that it would be better than adderol or ritalin?

I have used both before for ADD but they killed my strength levels not helped.

Thanks for the read man!

Looks like I need to make myself a very close Canadian friend to ship me some Modafinil.

adrafinil does not work as smoothly as moda did for me. be wary of liver enzymes when using adrafinil too… makes your pee smell funny :slight_smile:

as for adderal/ritalin replacement, it is tough to say. focus wise it works at a similar level but the overall feel is much less intense.
I would personally pay the extra money for the moda.

(and i wasn’t bashing steroids. i just dont like when products I use get linked to something I don’t personally condone.)

[quote]funmetal wrote:
dantheman wrote:
First, it does say steroids and only steroids now.

I’m very sorry but you’re wrong dude. It says clearly “Steroids and other drugs”.

Have a nice day…

funmetal[/quote]

I was looking at the dropdown menu and the top 30 most discussed. apologies for not catching the small print on the upper part of the page.

[quote]InTheZone wrote:

   Cost comparison from online source:

Adrafinil: 40 300mg tabs-40 bucks. dose one to two tabs/day

Modafinil: 20 100mg tabs-150 bucks. dose 200-400mg/day tops

                  ToneBone[/quote]

You are paying way to much for moda my friend…

[quote]dantheman wrote:
adrafinil does not work as smoothly as moda did for me. be wary of liver enzymes when using adrafinil too… makes your pee smell funny :slight_smile:

[/quote]

Both modafinil and adrafinil produce sulfur-containing metabolites that are excreted in the urine, which gives it the pungent smell.

[quote]Schwarzenegger wrote:
dantheman wrote:
adrafinil does not work as smoothly as moda did for me. be wary of liver enzymes when using adrafinil too… makes your pee smell funny :slight_smile:

Both modafinil and adrafinil produce sulfur-containing metabolites that are excreted in the urine, which gives it the pungent smell.[/quote]

I think i noticed it more with adrafinil simply because the dose is much higher. It is also safe to say, since adrafinil converts in vivo into modafinil, that it has more metabolites that could possibly be harmful…still up for debate however

[quote]InTheZone wrote:
dantheman wrote:
InTheZone wrote:

   Cost comparison from online source:

Adrafinil: 40 300mg tabs-40 bucks. dose one to two tabs/day

Modafinil: 20 100mg tabs-150 bucks. dose 200-400mg/day tops

                  ToneBone

You are paying way to much for moda my friend…

     No, actually I'm not. I just put up what people could expect to pay with minimal resource availability.

I would never pay that much for the stuff. I got lucky recently and a nice guy happened to give me a trial run. That’s why I have some real world exp to talk about.

   And yes I know about Adrafin's liver enzyme situation, that's why I indicated it had definite sides, but if you don't abuse the shit, one could use it sparingly fairly safely IMO. 

               [/quote]

did you consider all generics… because i pay about 20 bucks for 10 200 mg tabs of moda (about twice the price of adrafinil)

[quote]dantheman wrote:

did you consider all generics… because i pay about 20 bucks for 10 200 mg tabs of moda (about twice the price of adrafinil)
[/quote]

Modafinil is still patented. Well, at least they still have a particle size patent. I haven’t found any generics, though I’d be interested in who would sell it. The last company that tried (that I know of) was sued by Cephelon and they pulled out of the market.

[quote]dantheman wrote:
Schwarzenegger wrote:
dantheman wrote:
adrafinil does not work as smoothly as moda did for me. be wary of liver enzymes when using adrafinil too… makes your pee smell funny :slight_smile:

Both modafinil and adrafinil produce sulfur-containing metabolites that are excreted in the urine, which gives it the pungent smell.

I think i noticed it more with adrafinil simply because the dose is much higher. It is also safe to say, since adrafinil converts in vivo into modafinil, that it has more metabolites that could possibly be harmful…still up for debate however[/quote]

I agree with your line of thinking. I was just noting that it’s not solely with adrafinil, for those that didn’t know.

seriously screw the people flaming this thread, this was very interesting stuff. I think this forum should discuss new drugs like this type more often. It adds for a higher level of discussion.

I am quite happy, i love learning/discussing nootropics. just didnt like the placement of the thread…i’ll deal with it though

[quote]Schwarzenegger wrote:
dantheman wrote:

did you consider all generics… because i pay about 20 bucks for 10 200 mg tabs of moda (about twice the price of adrafinil)

Modafinil is still patented. Well, at least they still have a particle size patent. I haven’t found any generics, though I’d be interested in who would sell it. The last company that tried (that I know of) was sued by Cephelon and they pulled out of the market.[/quote]

Yea, the patent prevents generics from reaching domestic shelves, but there are things like “modalert” and what not…many Indian producers and distributors through the web have allowed me to afford an chemically identical product to modafinil… Bushy had a lot to say about this stuff, I think over on the Brain Function Booster thread…

[quote]InTheZone wrote:

   Cost comparison from online source:

Adrafinil: 40 300mg tabs-40 bucks. dose one to two tabs/day

Modafinil: 20 100mg tabs-150 bucks. dose 200-400mg/day tops

   As you can see the Moda which has zero sides essentially, is WAY more expensive to buy through this mode of transaction. That's why I'm going to give the Adra a go.

                  ToneBone[/quote]

I have a legal prescription for Modafinil, I use it off label as a brain function booster. I asked my doctor for it after my surgery last February, fearing that some of my intelligence may be removed along with the tumor.

In any case, I pay $260.00 for thirty 200mg tabs of Provigil, here in Connecticut at the local CVS pharmacy. Since there is no source that I trust (yet) for the knock off synthesis of this drug, I just have to bend over and take it up the tailpipe from Big Pharma. Since it DOES keep what few functional neurons I have left firing away.

YM, does insurance cover any of that? That’s a steep price.

[quote]dantheman wrote:
Yea, the patent prevents generics from reaching domestic shelves, but there are things like “modalert” and what not…many Indian producers and distributors through the web have allowed me to afford an chemically identical product to modafinil… Bushy had a lot to say about this stuff, I think over on the Brain Function Booster thread…[/quote]

Do you have any problems with customs and “modalert”?

[quote]Schwarzenegger wrote:
Modafinil is still patented. Well, at least they still have a particle size patent. I haven’t found any generics, though I’d be interested in who would sell it. The last company that tried (that I know of) was sued by Cephelon and they pulled out of the market.[/quote]

Cephalon’s patent on the drug expired in 2006. When a drug patent expires, makers of generics often rush to the forefront and capture business from the original drugmaker. However, this has not happened yet due to an interesting court case begun by Cephalon.

Four companies applied to the US FDA for approval to market generic versions of Provigil and they were all granted approval to make the generics. Cephalon filed suit against all these companies for patent infringement and the companies all settled out of court, in what some
have seen as a form of blackmail.

"The case, which was filed in June 2006, claims that Cephalon, the brand name manufacturer of Provigil, conspired with generic drugmakers Teva, Ranbaxy, Barr and Mylan to keep generic versions of Provigil off
the market. The case alleges that when Cephalon’s exclusive marketing rights were set to expire, the generic companies applied for FDA approval to market generic versions of the drug. Although the FDA determined that each company had developed safe, effective and bioequivalent generic versions of Provigil, they could not begin marketing the drugs because Cephalon filed patent infringement lawsuits against them.

Although they had strong arguments for invalidating Cephalon’s patent for Provigil, all four generic companies settled their cases with Cephalon. Under these settlement agreements, each generic company agreed to keep their generic versions of Provigil off the market until
2011 or 2012, in exchange for cash payments. The three payments to Teva, Ranbaxy and Barr alone totaled up to $136 million."

Apotex, another generic drugmaker, has sued all the parties involved alleging monopolistic practices.

“Apotex Accuses Cephalon and Four Generic Drug Companies of
Monopolizing the U.S. Market for Provigil”