8 Week Bloods: Estrogen Out of Control

Pharma / TRT
1

Hey fellas,

So my current protocol is 150mg Test E weekly, split into doses of 75mg. I administer on Wednesdays and Sundays. This blood work was taken Wednesday morning of week 8, before any injection.

I’m not running an AI currently, but looking at my blood work I’m strongly considering doing that. Alternatively I wanted to get some feedback on dropping my Test E dosage to 125mg per week and adding 200mg Masteron. I’d heard that might negate some of the estrogenic affects, without using an AI?

So far my sides are bloat, very watery appearance in face, puffy left nipple.

Any input more than welcome, I’m freaked out by these E2 numbers:

Hormone Comparison

Week 0 (7 Apr 2025) vs Week 8 (27 May 2025)

Total Testosterone: 492 ng/dL → 1,424 ng/dL
Free Testosterone: 92.5 pg/mL → 521 pg/mL
Estradiol (E2): 25.5 pg/mL → 91.3 pg/mL
SHBG: 36.3 nmol/L → 16.6 nmol/L
LH: 5.6 IU/L → 0.2 IU/L
FSH: 3.9 IU/L → 1.0 IU/L

2

What are the ranges? I assume you’re above range but need confirmation. Your dose is too high. Also adding Mast long term is a bad idea. DHTs are fine for cycling but not constant use.

3

Ranges as follows:

Total Testosterone:
33.9 nmol/L (976 ng/dL)
(Range: 8.64 – 29 nmol/L | ~249 – 835 ng/dL)

Free Testosterone (calculated):
0.851 nmol/L (24.5 pg/mL)
(Range: 0.2 – 0.62 nmol/L | ~5.8 – 18 pg/mL)

Oestradiol (E2):
328 pmol/L (89.3 pg/mL)
(Range: 41.4 – 159 pmol/L | ~11.3 – 43.3 pg/mL)

SHBG:
25.0 nmol/L
(Range: 18.3 – 54.1 nmol/L)

4

Two options… lower dose or add AI. Please don’t do both at same time. If you do add AI a little goes a long way. When I need it I take .125mg compounded for me with each injection (Anastrozole)

5

Would using a pill splitter on the 1mg Anastrazole pills work? Not sure how I’ll split that little guy 8 ways haha

6

Prob too much AI, but you could try a quarter. Just be careful you don’t tank your E2