Hey!
I changed Nebido from 500 mg every 6 weeks to every 7 weeks to see if my Hct at 50 would reduce. Now I have ED the last week and Hct about the same 49. So I asked to go back to every 6 weeks and a new doctor came in and said you have enough every 7 weeks because of my blood test results 
Free T at 8 T 461 and SHBG 42 at through every 7 weeks
On every 6 weeks I had at through free T 14 T 651 and SHBG 35.
Do you agree this is total non-sense? 71 mg per week (every 7 weeks) in TRT is really low right! Why keep me on this low dose producing low T symptoms?
I’m not an expert in testosterone undecanoate. But when you look at the pharmacokinetics, it seems to lead to a peak testosterone during the 2 weeks post-injection.
By week 4 it is already much lower and after 6 weeks it is barely above what it was pre-injection. That’s the problem with having the next injection when the active life is over. Here, it would make more sense to have the injection 4 weeks after the previous dose do maintain steadier levels. Often times, hormonal fluctuations are more important that the level per se.
I’d say that injective at the halfway point of the active life of the drug would be smarter to maintain more stable levels.
Look at testosterone enanthate, which has an active life of 10-14 days. So an injection frequency of an injection every 2 weeks it typically used. But if you look at the graph:
There is a pretty big difference in testosterone between day 1 (very high) and day 5 (about half as high). Yeah, technically, you still have increased test for 10 days… but in reality your levels might be “good” only for 4-5 days… with an injection frequency of once every 2 weeks, you’d certainly feel bad for half of that period, maybe more.
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So injecting more often could help but at every 7 weeks I know it does not work at this dose.
You are absolutely correct. 5 weeks would likely be best, but in the past 6 weeks hs worked out for you. But yeah, 7 weeks will get you too much of a rollercoaster.
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A lot of doctors, don’t care to optimize their patients, to make them feel their best.
Instead they focus on getting you into the normal ranges without giving any thought to your symptoms.
This is no way to treat a human being, let alone a patient.
You deserve better care!
I don’t understand why you would want to reduce your hematocrit at 50%. Guidelines state take no action until hematocrit is 54%, which was a number plucked out of thin air by doctors as a cut off.
My hematocrit is 51%, 1% over the range. I feel amazing.
Thank you!! This is what I feel as well.
I had hand numbness at night when sleeping and thought it was due to bad circulation while sleeping. Due to higher Htc. But I guess not the case. Anyhow I really regret I asked to reduce now! I am really angry I had 5 doctors prescribe T between 82 and 100 mg per week and now one says more than 71 is too much
Doubtful HCT is the cause. I get the same symptom if I don’t take enough iron supplement on TRT.
TRT can use up more iron in the creation of hematocrit.
Sadly, some guys derail their treatment because they’re making decisions and they don’t really understand what’s going on. It doesn’t help that the doctors don’t know what the f*** they’re doing.
Your previous labs were in the normal range, so I don’t understand how they could say those levels were too high, it doesn’t pass the laugh test.
Interesting because my ferritin was going low so I’ll keep an eye on that.
Yes previous labs were good so that’s why I’m WTF?
Instead of keeping an eye on it, you need to do something about it, it’s not going get better if you don’t change what you’re doing.
You have to take action.
Your HCT is expected to increase getting your ferritin levels up.
I actually need an enormous iron dose on TRT, but if I stop treatment, my ferritin recovers without iron supplementation.
I have already taken iron for say one year. Latest my ferritin is at 180 so I’m good now I don’t take it anymore. But will continue to measure it.
I find too little iron and too much can have similar symptoms. I’m actually coming down from some pretty bad symptoms after supplementing too much iron, ferritin was 198 and gums were inflamed, pissing blood, mood problems, muscle and joint pain, all of which are 95% gone.
Most doctors would’ve said your ferritin levels are normal. ferritin 80-130 is normal for me.
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