When you restore T to youthful levels, this increases your metabolic rate. When one has low thyroid function or adrenal fatigue, these systems can then not be able to support the higher metabolic rate and one can “crash”. If you look at testosterone, thyroid hormones and cortisol; you can make the analogy that these are a tripod of metabolic support and loosing legs is a problem.
KSMan do you believe it’s possible to “heal” your adrenals? I’ve been hearing horror stories that adrenal fatigue → low T is somewhat of a silent epidemic in the software world where I work and that many are stuck on TRT for life. Do you agree with this? Do you think being younger I have a chance of getting to the point where I’ll have ‘normal’ levels from restored adrenal function?
Also, can you elaborate on SSRI’s “rewiring” the brain. I get that altering the recycling of the serotonin system is unnatural but SSRI’s seem to be my only hope. I’ve tried therapy, neurofeedback, exercise, meditation, yoga, lots of supplements (5-htp/dlpa/multi/vitamin D), I’ve tried bright light therapy nothing seems to really do it. I have an extra-sensitive/anxious personality type that seems to burn out the pleasure center of my brain from overstress. I’m very close to giving up and going on an SSRI as I’ve eliminated all other options. How can I expect my adrenals to restore if all I’ve changed is no coffee and taking adrenal supplements, now? The underlying cause seemsto be an overactive/overanxious brain…
Also, update in labs for my benefit and anyone in a similar situation curious about how things’ve progressed:
total T: 660 (348-1197)
free T: 23.7 (9.3 - 26.5)
RT3 15.2 (9.2-24.1)
E2 13.1 (7.6 -42.6)
CORTISOL
AM 19 (13-24)
Afternoon 3 (5-10)
Evening 2 (3-8)
Midnight 1 (1-4)
So basically the body temps were either a result of two crappy thermometers or my thyroid normalized from the iodine replacement.
[quote]K_ wrote:
KSMan do you believe it’s possible to “heal” your adrenals? I’ve been hearing horror stories that adrenal fatigue → low T is somewhat of a silent epidemic in the software world where I work and that many are stuck on TRT for life. Do you agree with this? Do you think being younger I have a chance of getting to the point where I’ll have ‘normal’ levels from restored adrenal function?
Also, can you elaborate on SSRI’s “rewiring” the brain. I get that altering the recycling of the serotonin system is unnatural but SSRI’s seem to be my only hope. I’ve tried therapy, neurofeedback, exercise, meditation, yoga, lots of supplements (5-htp/dlpa/multi/vitamin D), I’ve tried bright light therapy nothing seems to really do it. I have an extra-sensitive/anxious personality type that seems to burn out the pleasure center of my brain from overstress. I’m very close to giving up and going on an SSRI as I’ve eliminated all other options. How can I expect my adrenals to restore if all I’ve changed is no coffee and taking adrenal supplements, now? The underlying cause seemsto be an overactive/overanxious brain…
Also, update in labs for my benefit and anyone in a similar situation curious about how things’ve progressed:
total T: 660 (348-1197)
free T: 23.7 (9.3 - 26.5)
RT3 15.2 (9.2-24.1)
E2 13.1 (7.6 -42.6)
CORTISOL
AM 19 (13-24)
Afternoon 3 (5-10)
Evening 2 (3-8)
Midnight 1 (1-4)
So basically the body temps were either a result of two crappy thermometers or my thyroid normalized from the iodine replacement.
[/quote]
This looks like adrenal fatigue to me. My understanding is you want your afternoon cortisol level approximately half of your AM level, i.e. yours should be closer to 9, whereas it’s 3. Your adrenals start off fine and then aren’t producing enough cortisol as your day progresses, which is where your fatigue is coming from in my opinion.
[quote]K_ wrote:
KSMan do you believe it’s possible to “heal” your adrenals? I’ve been hearing horror stories that adrenal fatigue → low T is somewhat of a silent epidemic in the software world where I work and that many are stuck on TRT for life. Do you agree with this? Do you think being younger I have a chance of getting to the point where I’ll have ‘normal’ levels from restored adrenal function?
Also, can you elaborate on SSRI’s “rewiring” the brain. I get that altering the recycling of the serotonin system is unnatural but SSRI’s seem to be my only hope. I’ve tried therapy, neurofeedback, exercise, meditation, yoga, lots of supplements (5-htp/dlpa/multi/vitamin D), I’ve tried bright light therapy nothing seems to really do it. I have an extra-sensitive/anxious personality type that seems to burn out the pleasure center of my brain from overstress. I’m very close to giving up and going on an SSRI as I’ve eliminated all other options. How can I expect my adrenals to restore if all I’ve changed is no coffee and taking adrenal supplements, now? The underlying cause seemsto be an overactive/overanxious brain…
Also, update in labs for my benefit and anyone in a similar situation curious about how things’ve progressed:
total T: 660 (348-1197)
free T: 23.7 (9.3 - 26.5)
RT3 15.2 (9.2-24.1)
E2 13.1 (7.6 -42.6)
CORTISOL
AM 19 (13-24)
Afternoon 3 (5-10)
Evening 2 (3-8)
Midnight 1 (1-4)
So basically the body temps were either a result of two crappy thermometers or my thyroid normalized from the iodine replacement.
[/quote]
I apologize for skimming down to your lab results and not reading your post well enough as it seems like you understand you’re experiencing adrenal fatigue. Have you read Dr. Wilson’s book on Adrenal Fatigue?
One KSMan is enough, thanks.
Reposting so he actually sees it:
KSMan do you believe it’s possible to “heal” your adrenals? I’ve been hearing horror stories that adrenal fatigue → low T is somewhat of a silent epidemic in the software world where I work and that many are stuck on TRT for life. Do you agree with this? Do you think being younger I have a chance of getting to the point where I’ll have ‘normal’ levels from restored adrenal function?
Also, can you elaborate on SSRI’s “rewiring” the brain. I get that altering the recycling of the serotonin system is unnatural but SSRI’s seem to be my only hope. I’ve tried therapy, neurofeedback, exercise, meditation, yoga, lots of supplements (5-htp/dlpa/multi/vitamin D), I’ve tried bright light therapy nothing seems to really do it. I have an extra-sensitive/anxious personality type that seems to burn out the pleasure center of my brain from overstress. I’m very close to giving up and going on an SSRI as I’ve eliminated all other options. How can I expect my adrenals to restore if all I’ve changed is no coffee and taking adrenal supplements, now? The underlying cause seemsto be an overactive/overanxious brain…
Also, update in labs for my benefit and anyone in a similar situation curious about how things’ve progressed:
total T: 660 (348-1197)
free T: 23.7 (9.3 - 26.5)
RT3 15.2 (9.2-24.1)
E2 13.1 (7.6 -42.6)
CORTISOL
AM 19 (13-24)
Afternoon 3 (5-10)
Evening 2 (3-8)
Midnight 1 (1-4)
So basically the body temps were either a result of two crappy thermometers or my thyroid normalized from the iodine replacement.
One KSMan is enough, thanks.
Reposting so he actually sees it:
KSMan do you believe it’s possible to “heal” your adrenals? I’ve been hearing horror stories that adrenal fatigue → low T is somewhat of a silent epidemic in the software world where I work and that many are stuck on TRT for life. Do you agree with this? Do you think being younger I have a chance of getting to the point where I’ll have ‘normal’ levels from restored adrenal function?
Also, can you elaborate on SSRI’s “rewiring” the brain. I get that altering the recycling of the serotonin system is unnatural but SSRI’s seem to be my only hope. I’ve tried therapy, neurofeedback, exercise, meditation, yoga, lots of supplements (5-htp/dlpa/multi/vitamin D), I’ve tried bright light therapy nothing seems to really do it. I have an extra-sensitive/anxious personality type that seems to burn out the pleasure center of my brain from overstress. I’m very close to giving up and going on an SSRI as I’ve eliminated all other options. How can I expect my adrenals to restore if all I’ve changed is no coffee and taking adrenal supplements, now? The underlying cause seemsto be an overactive/overanxious brain…
Also, update in labs for my benefit and anyone in a similar situation curious about how things’ve progressed:
total T: 660 (348-1197)
free T: 23.7 (9.3 - 26.5)
RT3 15.2 (9.2-24.1)
E2 13.1 (7.6 -42.6)
CORTISOL
AM 19 (13-24)
Afternoon 3 (5-10)
Evening 2 (3-8)
Midnight 1 (1-4)
So basically the body temps were either a result of two crappy thermometers or my thyroid normalized from the iodine replacement.
What a classy response.
We’re in this together. And a certain portion of it is pain/suffering. Which is why you should realize it’s serious. And why you should also realize how worthless interjecting advice into threads is when you don’t even bother to read them (this includes your second post).
[quote]K_ wrote:
We’re in this together. And a certain portion of it is pain/suffering. Which is why you should realize it’s serious. And why you should also realize how worthless interjecting advice into threads is when you don’t even bother to read them (this includes your second post). [/quote]
You’re right. You mentioned you were able to get your hands on hCG; did that improve your energy? As KSman mentioned, those with existing adrenal fatigue typically feel worse after a short while on TRT.
When T levels are low in a normal healthy man the Hypothalamus releases a “releasing” hormone (LHRH) that tells the Pituitary to release another hormone known as Luteinizing Hormone (LH). In turn, LH reaches the receptors on the Leydig cells within the testicles telling them to do their thing among which is the production of Pregnenolone from Cholesterol, Sperm and Testosterone among other things needed downstream in all hormonal pathways.
Exogenous Testosterone halts the HPT Axis (HPTA) and as such the testicles are no longer receiving LH. This is know by most of us as simply “shutdown” or “HPTA suppression.”
In order for men on a TRT protocol where they are in a state of shutdown/suppression to make up for the lost production of LH they will need to add hCG to their protocol which is a bioidentical form of LH (LH Analog).
- To produce Pregnenolone; hCG activates the p450 side chain cleavage (p450scc) enzyme which converts cholesterol to Pregnenolone.
- To produce the precursors for DHEA, Estrogen, Cortisol, Testosterone and DHT…back filling the pathways.
Low Pregnenolone levels will then correspond to low progesterone which in turn will correspond to low cortisol because the raw materials aren’t present.
All the recent labs are while on the TRT protocol in the sticky. HCG didn’t change things.
You could try Wellbutrin first, east to stop, SSRI’s not.
SSRI’s cause major changes in brain function and sexual side effects too.
Thyroid and body temperature issues are easily depressive.
So I’m wondering if I reconstituted my HCG right. I have an ache in my testes and they appear to be getting smaller…
I was given 10ml bacterostatic water (with benzol alcohol included) and 10,000 iu of HCG. I had a 3ml syringe and withdrew air from the HCG container and injected it into the BA container. Then, I withdrew 3mL of BA water and repeated this 4 times. I didn’t really swirl much but then I just stuck it in the fridge and I’ve been injecting 1/4mL EOD, since.
And since then there’s an ache and things seem to be getting smaller. Previously I was using premixed HCG bought from a compounding pharmacy.
Also, body temps are normal now. I think it’s 100% adrenal fatigue.
So you added 12ml BA water to 10,000iu?
If that was 10 ml, you would inject as you describe.
Is this hCG from a pharmacy?
If hCG is good, you can score positive on a pregnancy test.
No, 10mL BA water to 10,000iu. I was just trying to be specific, the fourth time was to get the remaining liquid.
Yes, it’s from a pharmacy.
Could I have wrecked it in the process? Exposing it to too much air? Damaged it somehow?
Should be OK. Get the prego test and know for sure.
I just went ahead and bought pre-mixed HCG from a compounding pharmacy.
3 injections later and testes still hurt and look smaller. Though I am sexually active and I wonder if somewhat frequent ejaculation is keeping things small.
I’m starting to think about switching to novolodex and staying on that until I heal my ‘adrenal fatigue’. Especially when it comes to HPTA shutdown. I don’t know if I want to do this practice for life mostly because of the stress about testicle pain and irriversable HPTA shutdown.
Was hCG shipped far? Have seen it destroyed that way. Best to have delivered dry and reconstitute yourself.
If hCG is good, you can score positive on a pregnancy test.
Get the prego test and know for sure.
Holy fuck KSMan you have helped so much! I got the progesterone cream with the DLPA and I’m having amazing results! Much energy. Much less depression. It’s pretty cool. Thank you!!
As far as the HCG goes the new vial was tested for potency before I bought it and it’s working. So things are good!
Perhaps also from the iodine.
[quote]KSman wrote:
Perhaps also from the iodine.[/quote]
Apparently I missed the importance of selenium. I’ve been getting temps <97 degrees. Woke up this morning with 96.3.
I don’t know whether to assume my thyroid is screwed or to just try and restore selenium levels and see if things will be fine.
Oops.