2.5 Years on TRT and Never Got Better

Internet forums are funny places. It’s humorous to watch people fight about something that it so individual to our unique selves… And to claim they’ve crushed someone.

@roscoe88 - I’m very interested to hear how your AI experiment goes. I know you’ve been through the ringer trying to get this figured out. You still taking armour? How are things going otherwise?

@equel
You know damn well you would have linked said thread if you truly believed that. No one cares anyway. It’s a TRT forum. Get your TRT right and tell people how you did it instead of being miserable.

The only thing he crushed is his own intellect. Ignore him.

I’m curious, did you get better. I’m in your same situation. TTR helped with everything except erections, they are always half hard

Do you take any pde5 inhibitors?

I have to, even with cialis my penis doesn’t get as hard as years ago, and I’m only 44. All my problems started after having a vasectomy 8 years ago, since the vasectomy I’ve never been the same

Do you modify your dose when you change frequency? From what to what?

How long did you stay on that dose/frequency before taking blood work? Anything else change? How is your diet?

When I was on 100mg test twice a week and HCG 250 IU’S twice a week, no AI:
TT: 1350
FT: 30
E2: 49
SHBG: 35
Then after watching dr Nichols, Jay Campbell and others saying that EOD injections is better, I started 50mg test EOD. After two month, I did my bloodwork:
FT:20
E2:59!!!
SHBG: 50
TT: who cares
With more frequent injections my E2 and SHBG went up.

@young_forever
My E2 is 80. Yours ain’t that high. Higher T = higher E. That’s how it works.

Do you take nitric oxide supplements? Upping nitric oxide could be key!

Very interesting your shbg and e2 increased while your dose decreased (50mg eod Is 175mg a week) and injection frequency increased.

I will say, with an increase in shbg, your decreased free t could be part of the problem. Your free t dropped by 33%. Did you change your diet at all? Start drinking more? Go on keto or start intermittent fasting?

I read on this board that shbg is related to insulin. More insulin, lower shbg…less insulin, more shbg. I wonder if there is something diet related?

And with an increased shbg, decreased dose, less free t, I surely wouldn’t expect to see higher e2.

Were the same exact tests performed (sensitive vs non sensitive) using the same assay’s? What are the reference ranges for each?

Do you have any other blood work/upcoming blood work scheduled?

What’s your protocol now? Sorry, lots of questions, but I’m curious.

@bcostigan41
Could you do the math on this for us, I don’t follow.

Mon-Wed-Fri-Sun = 50+50+50+50 = 200mg, no?

But then the next week is Tues/Thurs/Sat = 150mg. The trailing 7 day average is 175mg/week(7days)

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Exactly what @blizzardtest said. One week it’s 4 days, the next week it’s 3.

EOD dose times 7/2 = weekly amount or
EOD dose times 3.5 = weekly amount

I was taking 42mg EOD, which averages out to 147mg a week… But have read so much about daily dosing, I moved to 22mg ED 4 weeks ago. So far, so good, staying the course.

How have you been @phil65? Still taking 17mg ED? How are you feeling?

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No.

50mg EOD is 25mg a day. 25x7=175mg

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Maybe on high SHBG guys like me, more frequency is detrimental. When I was on 150mg test once a week, my E2 was always between 15 to 27.

My current protocol is:
Test cyp 100mg twice a week
Anastrazole 0.25 twice a week

The reason SHBG increased is because the T spikes were smaller injecting EOD versus twice weekly or once weekly.

That is why I believe less frequent shots are better for some people

Thank you, fellahs. I feel great on 17mg a day but both personal and business life got extremely hectic and busy and was thinking of going every 2 days to take something off my plate. LOL Also, when I’m old I may not want to pin every day.

So… I should do 34mg every OTHER day to ensure 120mg a week, correct? Maybe an extra mg on one of those days. LOL 7x17=119mg My Rx is 120mg a week.