I wouldn’t doubt it enackers
Tell me what happened
I would be more than happy to give you any guidance I can enackers.
@enackers
Please look at my profile and get my email. Email me so we don’t hijack this thread. I’m here for you dude.
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Libido is a function more of catecholamines than T. It is affected in that T and estrogen levels can have an effect on it. Try some L-Dopa (mucuna pruriens). Amphetamine salts (like Adderall and obviously other strong stimulants that are either re-uptake inhibitors or dopamine boosters) will boost it. Test boosts response to dopamine and other catecholamines somewhat, but not in everyone.
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Thanks and sent
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Libido, ED, and sexual function in general is extremely complex. Aren’t Catecholamines only one factor in Libido? I was under the impression that Androgens have multiple effects on sexual function, catecholamines, being only one of them. I was lead to believe Androgens among other biochemical compounds play direct and indirect roles in sexual functions including Libido in a variety of ways.
When a man is depleted of most androgens, as has been done in some forms of Androgen Deprivation Therapy, erections cannot be achieved and libido is void as far as I am aware. Is this due to androgens affects on catecholamines alone? Has it been proven that there is a way to restore normal libido and other sexual functionality to androgen deprived males using chemical compounds during Androgen Deprivation Therapy?
Amphetamines are often a cause of sexual dysfunction in men especially after prolonged use. Even patients receiving treatment for ADD using alternate stimulant SNDRI variants such as Methylphenidate sometimes develop sexual dysfunction disorders. Why would this be? Are you sure catecholamines are beak118’s issue after cycling LGD-4033? I don’t know that Androgens are the solution, or if biochemical intervention is necessary. Why do you believe direct DRI’s or NDRI’s would be warranted specifically in his case? Cocaine would induce heavy saturation on one end and high doses of Wellbutrin would induce low mediated saturation on the other end. Why do you think adultering any Catecholamine modulation would be specifically beneficial to his case over other modalities with the given information he presented? Wouldn’t interrupting Catecholamine modulation possibly be detrimental in the long run?
I f its an IR pills you can cut, smash, chew, parachute, do whatever you want its an Instant Release (IR) you dont want to cut Controlled Release (CR)
I’m not sure the answer to the questions later in your post, but I want to say that thus far the only thing I still struggle with is libido. Desire for sex is much weaker than it used to be. Rare spontaneous erections, however consistent morning wood. I believe this has to do with libido and the rarity of spontaneous erections, but throughout the day, testis are up tight and penis is shrunk (as if it were cold outside). I can feel that there is just no blood in there. Oddly though, with physical stimulation, I can achieve and maintain full erections and have sex to completion. Also, with physical stimulation, as soon as I’m erect, I feel as if my libido immediately comes back. This, coupled with all the “cognitive performance” and “increased sense of well being” claims surrounding SARMs, has led me to believe my issues are on the neural level. Also, with regards to Catecholamines, my libido responded really well to Tyrosine (precursor to dopamine) a few times. I’ve read that supplementing large amounts of Tyrosine suppresses the enzyme that metabolizes it into L-Dopa, leading to a rapid development of tolerance, which is why I turned to Wellbutrin for a long term solution.
I hope this helps. Might not be your problem but I’m the guy on this forum board that has had this issue and speaks freely with hopes that I can help others with my experience and etc…
I’ve been asking my doc and reading on this topic for a while now and I have found that erection strength and consistent morning wood can take up to a year or more for men on trt. During this time we have to be careful to not over stimulate or overdo it. We have to allow the body to heal and come together. Yes it’s hard because we get labido and aroused much easier when we start trt, but at times we look down and get angry when the Penis will Not get erect. Some do not get fully erect and others are touch and go.
Before trt and in early years I had huge issues and found The following to work if My quality of sex and erections is lacking. We should not play with it; don’t test it, and if you cannot get an erection do not force it. Especially if you feel the need to have sex and cannot get erect. There is a disconnect. The brain is fried for whatever reason.
Reasoning behind this. Our brain has been re wired to become erect with touching and physical stimulation. Or watching porn and self stimulation. It’s unatural.
Natural is When a man gets erect by looking at a woman and finding her attractive or if she’s touching kissing and rubbing on you. Pops a tent and is ready to go. Old age should not be a factor.
Today the cultprit for majority of our civilizations Ed problems are related to pornography and masturbation. This damages the brain and sex life. The brain gets used to being aroused when something is shown on the screen. This teaches the brain to use up all the chemicals pertaining to Sex (dopamine and etc) and Not when you have a woman in front of you and getting physical.
When someone with porn addiction gets into bed with a real woman the brain doesn’t know how to respond because it’s so used to having it happen on a screen. Neuroplasticity.
I could go on but you get the idea.
I had to Abstain for at least 2 months and got better over the course of 1 year. If i had watched porn for ten years it would take longer.
Porn isn’t the only way to make this Ed happen. It happens by over masturbation and stimulation. Especially if we do this daily or very often.
Neuroplasticity. Look it up. I hope this helps add to the discussion and helps you look at this from a different POV.
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Sorry been offline all day. I am not sure his problem is catecholamines, but responding to tyrosine in that way is meaningful. Personally, I have yet to see any correlation between T levels and libido or “morning wood”. A healthy dose of Adderall however…
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I also wonder, as do many men and doctors, what the cause of sexual dysfunction is. No one seems to have the answer but we do have a shoddy multibillion dollar pharmaceutical industry working on cure-alls. It makes sense from a business standpoint to invest billions in R&D into mens sexual health.
Hell we’ll buy knock off supplements from gas stations with nothing but caffeine in them if we think it’ll help our sex life cause there’s a huge demand for it…i.e. a huge market. There are prescriptions for Alprostadil injected directly into the Corpora Cavernosa at the base of the penis just to get an erection.
I’ve never heard of a doctor prescribe amphetamines to a patient for sexual dysfunction in modern times. I don’t know of any research that suggests it as a modality of treatment either.
Interestingly, Heroin (like almost every early opiate) was prescribed for too many years as a cure for gastrointestinal diseases, the typical cough, and run of the mill diarrhea. It is with out a doubt, extremely effective for these illnesses. There is no question as to heroin’s effectiveness for any of these issues, it cures or treats all of them 100%. While every opiate from codeine to fentanyl will cure a cough or bad case of the runs every time without failure, they are not prescribed for these issues often however. By standards of efficiency, they should be 1st line treatment protocols. Even Imodium is an opiate analog.
As far as Adderall, or amphetamines in general, regular use is known to cause sexual dysfunction and I would caution anyone about using them even if it’s addictive nature could be completely ruled out as contraindicative for that specific purpose.
I’ve done my share of stimulants and personally know a lot of guys who’ve suffered from sexual dysfunction from biochemical alteration through stimulant use. Super saturation of receptors as a regular practice is just generally going to cause more issues in the long run…everytime. There is way too many studies showing Methadrine, Dexadrine, and Benzodrine alone are extremely neurologically destructive to prescribe them for sexual dysfunction.
I do understand what you’re saying but I’ve used just about every stimulant there is on the market. This stuff is bad news down the road. Google the use of amphetamines in sexual dysfunction. This is the first NCBI article I pulled, dollars to donuts there are a ton of others despite pharmaceutical companies coming up with new unique ways of formulating alternative compounds of the same substances…It’s big money and big business, but amphetamines? They’ve been around forever. Put a different quantity of each amphetamine in one pill and brand it Adderall? Come on, they could get more creative than that to fool the the public. You’ve got to see right through this crap brother, it’s not rocket science. If I gave you a pill branded “Desoxyn” would you really think it was that different from that “clean ice” that Joe-Bob’s been cooking up in a trailer somewhere? I used to make the stuff when I was a kid. I can even tell you the most efficient way to clean up crank into 98% pure Methadrine without losing more than 35-40% of the original product. Some gasoline, kerosene, benzene and viola, you’ve got pharmaceutical meth. I would never press 120mgs into a pill and give to someone to get them horny…It works…better than other amphetamine salts…but for how long? What are the long term consequences?
There is a lot of empirical evidence and studies linking androgens directly to libido and sexual function. No androgens, no sexual function. Dr. Abraham Morgentaler (excellent source for TRT studies BTW) has suggested Testosterone as a treatment equivalent to PED5 inhibitors. Take a look at an example of a random Testosterone Sexual Function article I found.
I mean c’mon hardartery. Isn’t this study published in 2018 just a little suggestive? I mean, just look at the conclusion in the study brother.
@hardartery
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Let’s stop talking about what medicine will cure ED.
I have not found one man who has been healed with medicine. Only hormone optimization and that’s obvious fix. But even then many do not recover, because the LIFESTYLE. Self discipline and lack of understanding.
I remember staring at my doc asking “but why dude why”… this is not normal. “I don’t know it happens”. Here viagra. Here take androgel. Not one doc ever asked me “bro cut out the masturbation and porn”…: ffs your ruining yourself.
With trt and the discussions here we know that most docs are no longer detectives. They jsut can not operate and make a living because they are under pressure to provide. I can’t blame them. I blame the normal joe who accepts a pill for their symptom instead of demanding a cure. Decades later this is the norm and docs are cursed and left negative reviews if they do not dispense pills.
I also think allot of guys with ED do not give themselves time to Heal. They add more stimulation and try again. Or tetsotorne and continue trying… insanity
I see plenty of guys here and on other boards who says “I’m having erection issues” and they go on talking about how when they masturbate or turn in porn it’s not a normal erection and they are worried. Or even worse they take viagra on top of it… it’s like driving a car that needs coolant. You are ruining the engine hot.
Why not let the little guy rest and let the body heal. I never hear this anywhere. I have rarely seen this suggestion to men who come here with Ed issues. Check out the threads and it’s always check hormones; take viagra; it’s mental bro you have child hood mommy and daddy issues or fix your diet. Lollzzzz
When did it start? When the internet and technology blew up. The recent generations and very young men are having ED at high rates. Nobody is educating them.
I am starting to see this change and more talk is happening around this subject: especially now that teenagers are suffering.
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I don’t understand. Are you saying you haven’t recovered ?
T had helped me tremendously.
Been on the road, just read this. I was speaking personally about the lack of correlation, not empirically. T levels are not related to libido for me. Is it because I have ADD? Maybe. Adderall is a specific combination of two salts, different than Ritalin, which is why they don’t both work on the same person for ADD treatment. Adderall works for me, not Ritalin. It lowers my blood pressure and has even lowered my heart rate on occasion. It won’t do that to a non-ADD person, obviously. I hate the stuff and cannot comprehend it being addictive, but my biochemistry is not normal. It does, however, impact my libido in a positive way when I use it, which is not often because I hate the stuff, so I have to have a fairly substantial need (stress) to break out the bottle.
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Understood hardartery. I’m not trying to personally bust your balls at all. There are definitely valid reasons for stimulant prescriptions, legitimate ADD is one of them.
I grew up in an era where we took ADD scripts to get high.
I’ve gotten plenty high off Adderall (Dextroamphetamine/Levoamphetamine), Ritalin (methylphenidate), Dexedrine (Dextroamphetamine), Desoxyn (Methamphetamine), Vyvanse (lisdexamfetamine), All of them were prescribed for ADD, all are schedule II drugs, all of them hit uniquely similar receptors.
When Dexedrine reached rampant abuse levels it fell out of favor. Levoamphetamine was problematic in the mid 1900’s as well and disappeared for awhile. Both drugs were eventually combined and branded as Adderall. Pharmaceutical companies have been doing this kind of crap with addictive substances for years. They reinvent old addiction epidemics and blame the public for their mess so they can continue doing business as usual…That pisses me off to no end.
Many people do not enjoy particular substances. I know stimulant addicts that could never understand why anyone would get addicted to painkillers and vice versa.
Addictive substances serve good purposes as well. They are a part of medicine for a reason. When people like yourself can take these substances for the purpose they are intended for and do not have a particular affinity for that substances addictive properties, the substance is fulfilling a good cause.
Interestingly enough, painkillers such as heroin give me raging hard-ons…not typical at all. Opiates are know to cause sexual dysfunction but not in me at low doses. I would caution anyone from using opiates for ED however, least they end up with the addiction issues I have.
As you said, we are all biochemically unique. PDE5 Inhibitors have been proven to drastically help men with ED, anecdotally, empirically, and clinically, but that doesn’t mean all men respond to treatment with it.
The study in the last post above shows that Testosterone is proven anecdotally, empirically, and clinically to help men with ED and Libido issues, but that doesn’t mean that all men respond to treatment with it either.
I take no issue with taking amphetamines for a legit cause like ADD and getting the added benefit of increased sexual functionality without addiction issues.
Despite how I come off, I actually think it is awesome that you’ve found this solution. I have no issue with potentially addictive substances like amphetamines, opiates, etc… I have no issue with people who take these substances, whether they get high off them or not.
But I have a personal vendetta with the absolutely destructive nightmare caused by addiction.
I am very weary about anyone recommending an addictive substance to others for off label purposes with the chance that they go down a really dark dark path.
@hardartery
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I need to be clear in that I am not suggesting that people use amphetamines for libido. I am noting that it is not an uncommon effect, because libido has more to do with catecholamines than test. Estrogen and test clearly have an effect on ED. Chasing libido issues by focusing on them is not particularly useful. They are indirectly related. Indirectly. If there is a catechoalmine issue, it should be directly addressed in some way.
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The person who finds a true cure to ED will be a very rich man. Until then what a conundrum it is. I jsut thank the lord I don’t really have theee issues.
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Me too. ED is not on my wish list.
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I don’t think there will ever be a one-size-fits-all pill to cure ED. Just from the research I’ve been doing looking at all the different forum posts and studies published online and shit, erections and libido are influenced by too many factors for there to be one solution for them all. I started TRT, I’ve tried every aphrodisiac herb (unsuccessfully), I take cialis, I’ve tried Proviron, I take Bupropion, and I STILL struggle with my libido. But if there is some magic cure in the future, that guys gonna make bank.
True that. I am thinking the impossible. I think we have a good fix for labido. We just haven’t figured out why some can’t get erect even though the labido is high.
My limited understanding is starting to see that erections and erection quality has more to do with physical things like sex hormones and libido is more psychological, involving catecholimines and stuff, which makes a lot of sense.
Update for my thread: Confident that my low libido has to with dopamine, considering how well I responded to Tyrosine. My new thought is that perhaps I have high prolactin. I’ve never tested my prolactin, and have recently learned that many of the SARMs I’ve taken, primarily MK-677 (and LGD4033 to a lesser extent), can elevate serum prolactin. Considering that I ran MK-677 almost nonstop (on + off cycle) during my whole year or so cycling SARMs, I think I may have elevated prolactin levels. Prolactin also down regulates dopamine, which agrees with the fact that I responded so well to the Tyrosine.
I’ve considered high prolactin to be a potential issue in the past and have experimented with natural options like Vitamin E and Ashwagandha root with little success. I will say that I took 5g ashwagandha daily for about a month and did have slightly better libido, however in that time I also experimented with tons of other aphrodisiac herbs. I hate to admit this considering I know how improper practice this really is, but I’m going to experiment with Cabergoline (I could really only afford to get the prolactin blood test or to get the Cabergoline). I ordered the Cabergoline from a research peptides company with good reviews (30ml, 0.5mg/ml). I’ve read about the strength of Cabergoline so I’m going to tread vary lightly with my experimentation. With the typical starting dosage for severe prolactinoma patients being 0.5 mg weekly, I plan on experimenting with 0.1 mg (1/5 ml) 2x a week. Want to keep dosage low, considering I’m on Wellbutrin now and spiking my prolactin down could just create more problems with regards to dopamine.
https://www.nature.com/articles/3901483
This article demonstrates how Cabergoline can be effective in restoring Psychogenic erections and libido, something that I’ve struggled with immensely. Hate to have to play this one by ear, but I figured trying it out at a low dose is worth a shot and is relatively low risk, with side effects being not very severe and dose-dependent. Trial and error. I’m predicting this experimentation will be relatively harmless, but if anyone has a horror story they want to share about taking Cabergoline without getting prolactin levels checked first, do tell. I will be receiving it in the mail within the next 7 days.
Edit: Forgot to mention, though I think it is slowly improving, I do have some huge ass nipples compared to a lot of natty guys I know. Have never really felt any gyno, but the titties used to be a lot more sensitive to the pre-bench slaps I’d give them closer to when I cycled. On top of that, despite having built good pec muscle, my pecs looked a lot more manboobish after I stopped cycling SARMs. Dialing in estrogen after starting TRT has really helped this, but I feel as though my pecs are not as shapely as they could be… perhaps prolactin is the culprit. Again, hate to base this one off these inferences, but we’re on a budget here.
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