Why Oil?

Ok so I was trying to find some research that explains why certain steroids have to be oil based and couldn’t find anything on the subject.

I was just wondering why say test couldn’t be mixed in H2O as it would make it much easier to inject.

Anyway it was just something I was thinking about so if anyone has any good answers or could point me to some research that would be great!

I think that testosterone suspension is a water based steroid. I also think that being a water based injectable is why it burns like hell when you shoot it and also contributes to its short half life. But I could be wrong. I’m sure the home brewers have much more knowledge on this topic than I.

Because you are trying to make a solution. That means something has to be soluble in some liquid.

Most all of the steroids we use on the dark side are fat soluble. That means for them to dissolve - they have to be dissolved in fat…or…oil.

You can dissolve test base (or test no ester) in water, but once you add an ester - it becomes fat soluble. Water just won’t work. I am sure if you heated the water up hot enough, it would dissolve the steroids - but it will be just like trying to mix oil and water at that point.

Hope that helps out a little bit.

[quote]bushidobadboy wrote:
Steroids are generally lipophillic and hydrophobic. That is, they have an affinity for oil/fat and an aversion to water.

This is (if I remember my basic chem) because streoids are derived from cholesterol (a fat), and lack a polar group that would make them miscible in water.

Bushy[/quote]

AH gotcha thanks bushy! That makes sense to me now.

[quote]rainjack wrote:
Because you are trying to make a solution. That means something has to be soluble in some liquid.

Most all of the steroids we use on the dark side are fat soluble. That means for them to dissolve - they have to be dissolved in fat…or…oil.

You can dissolve test base (or test no ester) in water, but once you add an ester - it becomes fat soluble. Water just won’t work. I am sure if you heated the water up hot enough, it would dissolve the steroids - but it will be just like trying to mix oil and water at that point.

Hope that helps out a little bit. [/quote]

It does thanks rainjack! Now you have me searching for why we add an ester to test base! Haha

Lol ok so test base has a half life of 1 hour, makes sense why we add an ester!

[quote]CrewPierce wrote:
It does thanks rainjack! Now you have me searching for why we add an ester to test base! Haha[/quote]

That is simply because of half-life. Esters extend the absorption time of the hormone into the body. The longer the ester - the longer the absorption time.

Man I wish steroids weren’t frowned on so much as there must be a way to get the same benefits as long chain ester steroids but have it combine with water.

Oh well, until then I guess the heating pad will have to do!