I stopped taking AI 3 weeks ago I think. Since then, I’ve noticed my elbows don’t ache on presses. I am retaining some water I think, because my ring is tight first thing in the AM when it wasn’t before. I haven’t been getting up to piss 4-5 times a night. In fact, the last two nights I have got up at all. I’ve woke up a few times with wood, wood had been absent for a long time.
This could be a coincidence? I don’t have any written proof or studies to back up my observation. I got my doc to bump me up a bit, but the drawback is I have to do labs in 2 months. I will have to argue with him that I don’t want to take an AI.
I didn’t think I was taking much AI. 1/4 a pill 3x a week. But I guess it is some powerful stuff.
It isn’t a coincidence. Better joint health, better libido, better erections…you can thank estrogen for all of that. If you have optimized levels of free T, estrogen will provide roughly half of the benefits you are looking for on TRT.
Well, last night I didn’t feel tired. But now I have another issue. Last night I developed what feels like hard, sensitive tissue in my right pec. Along with it is a dull aching feeling there, along with tenderness to the touch.
This also happened when I first started trt, and my doc put me on 200mg per week with one injection per week.
I’d normally think this is due to high E2, and that I need to take an AI. But I’m guessing that @dbossa will say it’s not due to E2, and that it’s due to hormone fluctuations, and will go away on its own?
This is precisely what is going on and is exactly what my experience was when I stopped. It started to swell a bit and got tender. I kept checking it every day and then there was a point that it wasn’t getting any worse and just staying the same. After a few days of that, it started to shrink back on its own. I remember almost taking an AI probably 100 times when that happened lol! But yeah… That’s what most guys report to me…at least the ones that are gyno prone.
Just curious- I had the same lump form. The lump is still there and a bit tender. When the lump formed I dropped HCG, lowered my protocol from 200mg weekly to 140 and changed pin frequency from twice a week to ED and added a SERM (probably two many changes at once). My nipples are not sensitive, but I am not experiencing the same libido I had when pinning twice a week at a higher dose. Should I up the dose and keep ED or go back to my original twice a week at 200mg? I stopped the SERM, but still have it on hand.
You’re not experiencing the same libido because you dropped from 200mg a week to 140mg a week. I’d stay ED for now and raise your dose back up. Not sure why you stopped the SERM as that would have helped with the lump. Take 20mg daily until the symptoms subside. Keep in mind you’ll have hormone fluctuations from bumping your dose back up to 200mg. You can always consider raising it slowly over time.
Thank you sir. I will reactivate the SERM and bump the dose and see how it goes. I think I stopped it because I was worried about sides, and I was trying to simplify things.
Anastrozole reversibly binds to the aromatase enzyme. The body keeps producing aromatase. So after about 8-10 days the anastrozole is gone. There is an excess of aromatase in the body. This is where the rebound effect comes in. It should be short lived as the negative feedback from the increased E2 lowrs aromatase conentrations to more normal levels. Use tamoxifen if your nipple issues persist. Don’t go back to the AI. In general for those reading, It’s not a bad idea to take a single 20-30mg dose of tamoxifen about a week after AI cessation to smooth the transition.
I was wondering if you couldn’t do me a favor. Maybe ask around some of the doctors, and AI experts to see if the symptoms of chronic compartment syndrome could be caused by taking anastrozole while on trt.
@Gossamer I do not know a more brilliant person than Dr Serrano. If he says that, I would take it as gold.
When he doesn’t know, he says it. If he is giving this advice, trust me, he knows his shit more than anything else I know.
