Urologist Says Bioavailable T Means Not a Good Candidate for TRT

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@KCChuck

Nothing about my blood work or physical appearance suggests hypogonadism until you look at TT and FT. And with the current training in Urology still focused on TT alone and FT being confounding I can understand the docs slow play attitude. It doesn’t mean I agree, it just means I am empathic to his situation. My test numbers flirt with what I have discovered for many clinicians is not "clinically significant. The bioavailability is another matter and is what pushed this clinician to do something, well that along with my passion around the libido and ED symptoms.

Bioavailable T:

Test Dosage vs Levels for Cycle Recommendation

See first two pages of review article above. Bioavailable (“free” + “weakly bound”) T assay is a very standard result that attempts to measure non-SHBG bound testosterone by precipitating SHBG bound fraction using ammonium sulfate method. Testosterone that’s left is the human serum albumin bound test plus free test. It’s a long story how all these tests and terms came to be and if you want the gory details read the review above. Bottom line is that free T isn’t the end all be all as I me…

Test Dosage vs Levels for Cycle Recommendation

Answer here depends on what scheme you buy in Fig 4? What ratio of mechanism 4a vs 4b may be tissue dependent and if could very well be that both fT and SHBG-bound T both contribute to overall intracellular aromatization. Excellent questions and fun to ponder. Thank you! Quickly you find that many of the simple constructs used to discuss TRT (e.g., free up that T dude!) quickly become murky.

Glad you guys got it sorted out. Nice work and nice writing. Way 2 go and best wishes!