TRT: Most Probable Weekly Dose Range for Treating Male Hypogonadism

Just to repeat :slight_smile:

For those resolving symptoms at that dose, we can then move down graduallyā€¦ say 10mg a week, until the minimum amount required to resolved symptoms is attained. At this point, resolving symptoms has been achieved. Where their serum levels will sit at this point will be more or less irrelevant because if we lower dose further their symptoms will return and will completely undermine the purpose of the treatment to begin with.

Haha! Youā€™ll be down to 100 mg/week by dinner tonight :-). Take it easy man. I wish you the best.

Just to say this advice wasted 8 years of my life, made my wife miserable, and has very possibly shortened my life.

Yes that is true. Some men donā€™t handle high androgens. Some donā€™t feel much different running 10X top of range (I feel good at all the doses I have tried 150 - 600).

I think there is value to a more pragmatic approach like Dbossa takes, and a more mathematical approach like readalot takes. If they worked together they would have experience and science to back them.

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If it took 8 years to determine ideal protocol I urge you to slap your provider on my behalf.

There is no reason why it should take any longer than a year at the MOST to get a protocol dialed in, even for an outlier.

The Voltron of TRT! ā€œIā€™ve got the brains, heā€™s got the looksā€¦letā€™s help lots of people.ā€

j/k on both @dbossa. You guys take it easy.

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And seriously @dbossa, get the hell of this forum and Facebook. We both need to work on our OCD and perfectionism.

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I canā€™t really blame her. Most of what you read is of the mindset more is better. But hereā€™s the approach I wish she would have taken, ā€œYour test results reveal an 81 TT, letā€™s see what happens if we bring you up to 400.ā€ Would have saved me those 8 years of countless blood donations, countless nights of frustration for the wife, countless bouts of insomnia, and countless episodes of ā€œdude, why is your face so redā€.

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Well, I think both of you are credible. Now the problem with knowledge through experience is that it is harder to logically defend. Seeing a pattern over and over and using that as the basis of your argument can be picked apart. The problem with the scientific / mathematical approach is that on paper doesnā€™t always work out. I had lots of ideas that were pretty solid as far as theory goes. I think many of them are stupid now that I have some experience. I think Henry Rollins has a good quote on this principle. Something like knowledge without experience is BS. Rollins has a lot of good quotes, and a song about squatting (On my way to the cage).

Note, just for the interested reader, another good study. Iā€™ve linked this before and no oneā€™s going to read it anyway. Note these were young guys with very reasonable metabolic clearance rates:

Look at the left set of panels (to convert to ng/dL multiply by 100):

Older guys on average are going to have slower clearance rates and higher SHBG. So if you really want to mess some older guys up real bad (especially ones that donā€™t work out), put them on 150 mg/week of T ester and watch the shitshow begin. No offense. Howā€™s that for experience @mnben87?

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Have a good time. Thatā€™s the thing with AAS, probably better to not have too much experience.

Ha! I think it has been made fairly obvious that one of us puts way more value on the tiniest of details than the other. I will let you guess which of us I am referring to :wink:

This is what I do for a living dudeā€¦being correct at the tiniest level of detail.

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That is true. I donā€™t plan on ever using ā€œhighā€ dosages (subjective, I know). It is amazing what the pros get away with though (Dallas McCarver had a TT of 55,000 ng/dL when he died). I guess he didnā€™t get away with it. Logistically, I canā€™t fathom making that happen (I would have noticeable size just from the oil depots).

Yeah, that was something wasnā€™t it? Death Cult supreme. Glad my ticker canā€™t handle very much, probably saved me in the long term.

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She would still be targeting a number. It is a great to make this argument now that you know what your number is but without knowing the number there was no way she could have had a number to Target to begin with. Itā€™s always a guess when you start and by simply using a bit of logic and critical thinking you can get that ideal protocol dialled in relatively quickly with a little bit of effort and patience.

And glad we agree now that final dose much closer to 100 mg/week instead of 150 mg/week for majority of dudes. See I will say majority, not vast majority, just to compromise with you. We are making progress man.

She went from 1 to 10 without considering how I would feel at 3 through 7. Notice I say ā€œhow i would feelā€. I donā€™t see anything wrong with ā€œtargeting a numberā€ and then slowly titrating up until the patient feels better.

I never once said that. Ever. Youā€™re still misunderstanding. I used an example of a single man. How how does this even possibly relate to all men? You took a single example and then stating that Iā€™m making a blanket statement regarding all men. I think you should re-read what I said again because I canā€™t be more clear if I tried.