TRT Journey is Starting, Crazy Lab Results

Pharma TRT
21

The only major health concern is elevated E2. You would do a lot better nearer to E2=80 pmol/L
Anastrozole, 1mg/week taken when injecting would be good. Pill splitting difficult, could try .25mg at time of injections/
E2 is bad for:

  • mood
  • weight
  • prostate
  • cardiovascular health
  • DHT and T do not cause prostate problems, E2 does.

I like your hormone levels.
Your T ranges are modest.
You have not listed your age.
TRT goals are youthful levels, not age adjusted.

TSH .20 (.35-5.mlu/L)
Free t3 5.1 (2.6-5.7 pmol/l)
Free t4 17 12-22 pmol/l

Eval overall thyroid function by checking oral body temperatures:

  • when you first wake up, should be 97.7-97.8, higher is OK, 97.3 is a problem
  • also mid-afternoon should be 98.6F/37C

If body temps warm, that is expected.
If body temperatures low, rT3 probably blocking ft3

Is your thyroid enlarged, lumpy, asymmetrical?
If you were not getting enough iodine for years, then elevated TSH can cause the above and the lumps produce thyroid hormones outside of the thyroid feedback control loop. The elevated T3, T4 levels then depress TSH. So iodine deficiency can may one hypo then hyper later on. Doctors never ask about iodine intake.

Exhausted: I wonder if your hypothyroidism is exhausting your adrenals.
You could have AM cortisol checked and do at 8AM
Speaking of adrenal fatigue:

  • a lot of stress in your life or major stress events
  • accidents
  • acute or chronic inflammation/infections
  • over training
  • crash/starvation diets
  • over stimulation, caffeine, stimulants, thyroid, rT3
  • see thyroid basics sticky and ^F search for:
    – adrenal fatigue, Wilson’s book

Please read these stickies:

  • advice for new guys
  • thyroid basics

Please post more info about you.
Do you have this lab data:
fasting cholesterol
fasting glucose
CBC
Hematocrit [HTC]
AST/ALT
AM cortisol
rT3

22

New results came in, and looking good. I scaled my dose lower prior to this bloodwork, going from 120MG every week (three weeks prior to blood work), to 100MG, and then to 80MG/week after that I took this blood test. My doc is conservative and had lowered me to 80MG a week rather than add in an AI.

Overall feeling very good. The exhaustion has passed with TRT, I did saliva cortisol tests with the clinic and over the course of the year have normalized, the thyroid while still borderline hyperactive is not displaying bad symptoms (other than I can stay at 12% bodyfat with relative ease). I did have an ultrasound and all was normal.

So here is the new bloodwork:

E2 94 range <150pmol. That is 25pg/ml.
Test 30.7 nmol/l range is 8.4-28.8
Free Test 545 pmol range is 196-636

HSCRP is down to .4

TSH was .41 miu/l range is .30-4.00

I am 42 years old, currently in good shape 12@ bodyfate measured on the on those scales that use current to measure, and 13.4% measured by a bodpod. TRT has brought me back to life, so on for almost two years and doing very well. Other relevant blood work is:

HTC .467 l/l range is .40-.50
Cholesterol 5.33 moll/l
HDL is 1.30
LDL is 3.74
All other work was normal?.expect I have a low platelet count.

Currently platelet count is 131 ref range is 150-400 (units are x E9/l).

I have to figure out the implications of that, never seen that before, and as usual seems most on TRT (based on Tntaion forum search) actually see high platelet count.

The other direction for me is seems a lower dose of TRT actually is ideal ? E2 in check, T at the top end of the range ? my initial reaction was to resist my doctor at lowering me back to 100MG (and then trying 80MG) a week, but this seems to be the minimally effective dose.

23

Hoping my doctor doesnt ratchet me back!

Current results on 100Mg test per week, E3D injections:

E2 95 pmol/L (range less than 150). (that is 25 pg/ml)
T 35.8 nmol/L (range is 8.4-29.8)
Free T 726 pmol/L (range 196-636)

So ideal T level, good E2, but out of range…which means my great, but conservative doc will likely pull be back to 80MG a week.

Testing is in Ontario, Canada…seems the ranges are really conservative.

24

Really interested in hearing your how you came to finding a good doc in ontario, Canada. I haven’t had te chat with my dr yet.