Why not anastrozole?
Your target is E2=22pg/ml - 80 pmol/L
Liver health can be a factor with high E2.
Prolactin might be a factor with your low-T.
Did you test LH/FSH before TRT to see if problem is with testes or pituitary?
You tested E2 before TRT?
T levels should be higher for that dose. You may be a fast metabolizer. Please inject T twice a week and always do labs half-way between injections to minimize effects of lab timing.
SHBG is quite decent considering that elevated E2 increases SHBG.
All other bloods look good. Maybe not.
Levels and ranges please: -as available
hematocrit
RBC
AST/ALT
TSH and other thyroid
hemoglobin
fasting cholesterol’
fasting glucose
cortisol with time of day
With your high T dose and high E2, your suggested dose seems low. Pick a dose and keep steady, if working OK for you, you should feel a difference in 7 days. If seems OK, do E2 labs in 2-3 weeks to see where you are. If considering anastrozole, you could try 1mg at time of injections. But start at 0.5mg for a few days to make sure you are not an anastrozole over-responder with crashed E2 - not rare.
Please read the stickies found here: About the T Replacement Category - #2 by KSman
- advice for new guys - need more info about you
- things that damage your hormones
- protocol for injections
- finding a TRT doc
Evaluate your overall thyroid function by checking oral body temperatures as per the thyroid basics sticky. Thyroid hormone fT3 is what gets the job done and it regulates mitochondrial activity, the source of ATP which is the universal currency of cellular energy. This is part of the body’s temperature control loop. This can get messed up if you are iodine deficient. In many countries, you need to be using iodized salt. Other countries add iodine to dairy or bread.
KSman is simply a regular member on this site. Nothing more other than highly active.
I can be a bit abrupt in my replies and recommendations. I have a lot of ground to cover as this forum has become much more active in the last two years. I can’t follow threads that go deep over time. You need to respond to all of my points and requests as soon as possible before you fall off of my radar. The worse problems are guys who ignore issues re thyroid, body temperatures, history of iodized salt. Please do not piss people off saying that lab results are normal, we need lab number and ranges.
The value that you get out of this process and forum depends on your effort and performance. The bulk of your learning is reading/studying the suggested stickies.