Many have brain fog from:
- low T or low T and elevated E2
- high T on TRT with elevated E2
- low thyroid function
Many going on TRT have fog lift quite fast, but depends on how long the brain has be suffering low T. Elevated E2 often spoils the show. E2 management is almost always mission critical.
Some guys have mood issues despite other hormone interventions. These can be neural transmitter related or other things that affect overall health.