Strange Bloodwork. Help?

Testosterone resistance isn’t your problem, the problem is your liver is producing too much SHBG. The causes are many, some believe it may be a chemical in the environment, sometimes it’s just genetic. SHBG scavenges sex hormones and when elevated will choke your free testosterone into oblivion, your only hope is large weekly injections of T, you’ll likely need supraphysiological doses of T to push SHBG down to a lower level.

There lies the problem, insurance doctors typically don’t allow supraphysiological doses, insurance companies have set a limit at 800 ng/dL and for this reason you may need to go private. I don’t understand how your doctor arrived at testosterone resistance, you barely have any bioavailable or free testosterone circulating in your body. The bound hormone (Total T) is useless to the body.

When your pituitary gland detects low levels of free testosterone do to the SHBG binding it all up, so the pituitary gland starts pumping LH hormone in an attempt to get the testicles to increase testosterone production in order to increase free testosterone.

Sadly your pituitary gland will never be able to force your testicles to produce enough testosterone to compete with your very high SHBG.

TSH and Free T4 really doesn’t show a complete picture, Free T3 is the active free hormone and it’s not tested. Reverse T3 can block Free T3 at the receptors if elevated. It seems this doctor isn’t testing Free T or Free T3 hormones, these are the more important tests as a bound up hormones are unavailable to your bodies tissues.

A lot of doctors will struggle in understanding of male hormones. I was forced to go private as insurance based healthcare is in short supply of hormone specialists. None of my endo’s knew what to do or how to manage my symptoms and seem disinterested in treating me.