I understand. I am trying to tell you that iron loss can affect thyroid function and energy levels. fT3 was not tested. As your AM temperature was low, fT3 may well be low. You need to test early AM temperature AND mid-afternoon.
Have you read the thyroid basics sticky where this is discussed?
In there, I discuss that some guys are anastrozole over-responders who crash E2 on standard dosing. They need to stop for 5-6 days then resume at 1/4th the suggested dose, try 1/16th mg E3D. Need to point out that one guy needed to go to 1/8th suggested dosing. Some people have different enzymes.
I also posted this in this thread April 21st.
E2 < 5 is bad. Lets assume now that you are an anastrozole over-responder. Stop anastrozole for 5-6 days to allow to wash out, note how you feel as E2 increases. Then resume taking 1/8th mg at time of injections. Do manage small doses, dissolve anastrozole 1mg/ml inn vodka and dispense by volume or by drops. A graduated dropper bottle is good.
Question about the low dose Anastrozole. Rather than do the volume method, should I get it compunded at very low doses, say 0.05mg capsules? Would that be more accurate?
Iām a little confused about the dose recommendations. Should I be taking 1/4 of my previous dose of 0.25mg for 0.0625mg, or 1/4 of 1mg (i.e., 0.25mg)? I assume itās the former, as I over responded on 0.25, or are you saying then take 1/8 of that 1mg for 0.125mg?
Welp, blurry vision is back after my first dose of Anastrozole in 12 weeks (first re-dose was 3 days ago) I never thought the two were related until I went off previously, this confirmed it though. I also believe it caused floaters for me 6 months from the reduction in E2 below normal range.
If anyone could help calm me down or bring more attention yo whether or not I am developing gyno that would be great. Getting really paranoid over here, I guess my first gyno scare is happening! Or maybe not a scare, but wake up call! I have a doctorās appointment scheduled for next Tuesday but I can get in earlier if needed. Feel free to make fun of me I deserve it!! Thanks!
As stated in another thread, that KSman asked me to consolidate.
I got diagnosed with mild gnecomastia in both breasts.
Question regarding gyne tho, that I forgot to ask the Dr, who didnāt really want to sit there and argue with me and said itās gyne and come back after Iām off all meds to discuss surgery. He said itās mild, and unless Iām very unhappy, he doesnāt recommend surgery.
I just have questions about gyne: is it normal to feel lumps from my armpit all the way to the side of my nipple, but not directly behind my nipple? I was unaware that gyne extended that farā¦which is leading me to believe that maybe the lumps Iām feeling arenāt related. The doctor at first didnāt feel the lumps until I pointed them out, then he felt for a second and said yeah itās probably related. But he didnāt feel how far they extended, i.e. to the armpit.
Unfortunately, the doctor is supposedly the father of gyne surgery, so my hope that he is wrong is futile :(.
What does everyone recommend as far as immediate treatment?
I went off TRT completely, but have maintained Arimidex 0.25 EOD. And will have nolvadex on hand by mid week.
Canāt stop living in the past with " why couldnt I have listened to KSman and take a very low liquid dose of AI". Itās really depressing to think about. How do you all stay sane with gyno and not turn into even more of a biych than we already are?
My pipe dream is to recover to the point that itās unnoticeable to the naked eye. Eh, let me dream!
Iām going to be starting Nolva Wednesday. Any pointers? Should I drop the Anastrozole? I also have letro coming this week too.
Whatās the best for stopping gyno and reversing it, if thatās even possible.
My E2 is back to 20 on sensitive test, so i figured Iām out of the woods with gyno getting worse at this point. Ahhh
And I got gyno with E2 of 38 on sensitive, with 877 total test. My TT to E2 ratio was great. Why did this happen?
Just a brief update. Maybe Iām imagining things, but it seems my gyno has lessened, with my nipples consistently smaller. I started the Nolvadex yesterday at 60mg, and will continue that for a total of 5 days then go down to 20mg a day for another 7 days.
Iām going to keep a close on eye the gyno and will post pictures over the next day or so. My nipples seems to be close to baseline (before TRT), but again, maybe itās placebo and my brain is being a douchebag.
Do not stop anastrozole!
You do not need letro. Letro dose/response can be āunpredictableā.
You found a good balance, donāt fuck it up.
Very low E2 will make you feel unwell.
Your labs look very gyno friendly, let tissue respond to this.
Adding Nolvadex is simply wrong and 60mg could greatly increase E2!
T4 is well below mid-range
better to test fT3 and fT4
fT3 is the active hormone
āā"
T3 uptake: This test does not measure thyroid function at all, but thyroid-binding protein saturation. A high T3 uptake means binding proteins are more saturated than normal. When combined with a total T4, this test allows the āfree thyroid indexā to be calculated, thus correcting for low or high thyroid binding proteins. For example, a child with TBG deficiency has a low T4 and a high T3 uptake, so the product of the two, the free thyroid index, is normal. Since free T4 can be measured directly and inexpensively, there is no reason at all to order a T3 uptake. A somewhat low or high T3 uptake is the presence of a normal TSH level is not clinically relevant.
āā"
[I have seen cases for spme guys where SERMās do not do anything re gyno.]
The primary goal is E2 in lower 20ās and you are there now.
T3 uptake. This test does not measure thyroid function at all, but thyroid-binding protein saturation. A high T3 uptake means binding proteins are more saturated than normal. When combined with a total T4, this test allows the āfree thyroid indexā to be calculated, thus correcting for low or high thyroid binding proteins. For example, a child with TBG deficiency has a low T4 and a high T3 uptake, so the product of the two, the free thyroid index, is normal. Since free T4 can be measured directly and inexpensively, there is no reason at all to order a T3 uptake. A somewhat low or high T3 uptake is the presence of a normal TSH level is not clinically relevant.
I know that you are getting iron infusions. But your labs still suggest the need for an occult blood test as HTC is way too low VS T levels.
