SERM or AI on TRT?

Looks like he is testing total estrogens.

The concern is FT–>E2 and we test E2 and OP does not have that lab work and his doctor seems unworkable.

OP:

We need labs in list format, properly identified with lab ranges.

You need to modulate aromatization with anastrozole.

SERMs typically increase E2 while reducing visibility of estrogens in Selected tissues. SERMs do not reduce estrogen levels. SERMs useful short term to deal with gyno, but lower estrogens via AI is the solution.

High E2 causes liver to produce more SHBG that leads to more SHBG+T that inflates TT, reduces FT and overstates your T-status.

E2 can be increased by impaired liver clearance.


Please read the stickies found here: About the T Replacement Category - #2 by KSman

  • advice for new guys - need more info about you
  • things that damage your hormones
  • protocol for injections
  • finding a TRT doc

Evaluate your overall thyroid function by checking oral body temperatures as per the thyroid basics sticky. Thyroid hormone fT3 is what gets the job done and it regulates mitochondrial activity, the source of ATP which is the universal currency of cellular energy. This is part of the body’s temperature control loop. This can get messed up if you are iodine deficient. In many countries, you need to be using iodized salt. Other countries add iodine to dairy or bread.

KSman is simply a regular member on this site. Nothing more other than highly active.

I can be a bit abrupt in my replies and recommendations. I have a lot of ground to cover as this forum has become much more active in the last two years. I can’t follow threads that go deep over time. You need to respond to all of my points and requests as soon as possible before you fall off of my radar. The worse problems are guys who ignore issues re Thyroid, body temperatures, history of iodized salt. Please do not piss people off saying that lab results are normal, we need lab number Aand ranges.

The value that you get out of this process and forum depends on your effort and performance. The bulk of your learning is reading/studying the suggested stickies.