Problems with TRT After Taking a Certain Supplement

Sorry, but this is just a very poor, dismissive, completely uneducated assessment of the situation with PSSD. Just because the EMA has recognized it does not mean PSSD is widely known and accepted by people or the overarching medical community. In fact, in spite of the EMA recognition people are still battling to have PSSD recognized, especially outside of Europe. I would bet that 98+% of doctors in North America are still completely unaware of PSSD and deny the possibility of persistent issues.

You are not in any position whatsoever to discuss what is or isn’t statistically probable. One of the handful of doctors that actually recognizes PSSD in the United States and accepts sufferers as patients is a world renowned sexual medicine expert. It is his belief that up to 1/5 (20%) of people who take SSRIs end up with persistent dysfunction of some sort. The problem is that not everybody attributes it to their medication, and the variability in symptom severity between people.

Brushing PSSD off as being part of someone’s depression is an argument that doctors who do not recognize PSSD like to make, but under the slightest bit of scrutiny simply does not hold up. Depression does not make your genitals go partially or completely numb. Depression does not give you genital shrinkage. Depression does not cause you to lose your nocturnal and morning erections. These are all objective, physiological symptoms.

This isn’t even getting into the persistent, non-sexual symptoms of PSSD that people did not have prior to SSRI usage and one of the reasons that ā€œPSSDā€ is a misnomer. There are plenty of studies proving epigenetic alterations and reproductive system toxicity by SSRIs so I don’t know why it’s such a stretch to believe issues could be persistent/permanent and in larger numbers than one would think.

LOL, at no point did I state any of the that shit, but whatever. I said it’s unlikely a PSSD diagnosis is more of a statistical probability here than simple ā€˜deca dick’ considering you’re posting on a hormone forum where at least 60% of the posts involve sexual side effects from said exogenous hormone use.

Good luck sorting out your PSSD though.

The guy whose career and reputation depend on their being more patients with a specific disorder says that more people have that specific disorder.

PSSD may very well be a thing that’s more widespread than it’s believed to be now. In fact I would bet that it is. The long term downstream effects of SSRI use are largely ignored. But if 2020 has taught us nothing else it’s that the word of public health officials and private doctors with agendas are to be taken with a grain of salt. Evidence first, conjecture second.

That makes no sense. We all know 19nors can be nasty substances in that regard with long term suppression but what does deca have to do with this individual case? He never took deca. You said it was either testosterone or a lack of SSRIs causing his issues and are dismissing PSSD because we are on a board that condones hormonal manipulation?

And you did say or allude to all of those things, you’re basing your perceived rarity of the condition off one study of 5-10 people.

I understand that viewpoint, but believe me when I say there is more to lose taking a stance accepting PSSD than anything else.

Bottom line is this doctor just had a lot of people going to him on their own accord over the years complaining about enduring issues from SSRIs that he noticed an undeniable relationship. This isn’t a case of self interest this is ā€œI have seen enough to recognize there is something to this.ā€

Plus, he’s done enough Doppler Ultrasounds picking up scar tissue in the genitals of people who claim to have PSSD and done enough nerve testing showing severe deficits in sensitivity to support this trend with objective evidence, among other things.

Considering the hundreds of millions of patients globally having been over prescribed SSRI medications for the last 25 years, why aren’t there several massive class action lawsuits against the pharmaceutical industry over PSSD? In the overly litigious cultures we live in where you can sue a company for breathing, how can it be that 20% of former SSRI users aren’t currently suing their doctors and anybody else they can? There are currently 40 million people in the US on SSRI’s, and your assumption is 8,000,000 now have PSSD? If that were the case, we wouldn’t be on the internet arguing over it’s rarity as it would be front page news, and certainly would have more than one doctor who specializes in it, and more than a few small scale studies.

It exists, but there are a host of other causes of sexual dysfunction far more likely than PSSD in this case, obviously so considering the forum you are on.

I’m not sure I can be any more succinct. Clearly, you have a hard on over PSSD, as you have only 4 posts here and all are either diagnosing people over the internet with PSSD, or arguing about PSSD.

I lost access to my other account.

This is an issue with far more nuance than you can comprehend. It is an incredibly challenging condition to pursue litigation for, for many reasons. Between SSRIs and SNRIs there are over a dozen medications that have the potential to trigger such a condition. That means that you would have to assemble enough people to file a class action against the manufacturer of each and every one of the different medications.

Factor in the stigmatization of sexual dysfunction and shame associated with such a condition, as far as people seeking legal and medical assistance and you are fighting an uphill battle to organize. Mind you Eli Lilly put a warning on Prozac about issues remaining following cessation back in 2011 so you have a manufacturer actually admitting PSSD exists. Drug companies knew about this well before then.

There are different variations of genetic susceptibility to PSSD - as I mentioned, some people respond worse than others will. Some people will not experience any negative impact, some will experience ā€œmildā€ PSSD that is easy to attribute to other things (aging, stress, etc) and some people will have their lives destroyed.

Litigation is messy and takes time. For example there are just now lawsuits going through courts for Post Finasteride Syndrome and that is a single drug/manufacturer that has had a foundation and organized community behind it for years.

It doesn’t matter what board we are on, I am addressing this particular case and given what OP described I find it difficult to see how PSSD is an unreasonable suggestion, particularly what triggered the issues for him (inositol). TRT alone + Inositol will not cause issues. PSSD + a serotonergic substance can.

It’s not like this guy has been blasting Deca and Tren for years.

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