If you took 1mg a day it would take 5-7 days to reach final blood levels, a half-life effect. So your levels from a single dose are not as high as you might think. You can start the new dose in 4-5 days.
Follow up labs: TT, FT, E2, LH/FSH
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I ended up going back on the opioid due to my chronic pain still being too much to handle, and as such, my T levels plummeted, but it seems my E2 has gone down to normal levels after 6 weeks of .25mg EOD of anastrozole.
Any recommendations for a non-fertility impacting TRT regimen (I plan on having kids) for me since I plan on staying on the opioid long-term? I see the doctor on Monday and it seems that I can pretty much recommend whatever I want and get it (not that that is actually a good thing), but the doctor has already mentioned hCG, Clomid, Novaldex as options, either as standalone treatment or in combination, but said we will talk more on Monday. So I want the real pros opinions!
After only 6 weeks of opioid use my Total T went from ~1,000 while on the Clomid to 215 while off the clomid. See most recent bloodwork:
Current Meds:
anastrozole .25mg EOD 6 weeks
Opioid a lot ED 6 weeks
Previous Meds
Clomid .25 ED for 12 weeks
Opioid a loto ED 12 weeks
11/23/2016 while off Clomid for 10 weeks and on Opioids for 6 weeks and .25mg EOD of anastrozole
TT: 216 ng/dL (Normal range: 250-1100)
FT: 28.4 pg/mL (Normal range: 35-155)
E2: 22pg/mL (Normal range: <39)
LH: 3.4 mIU/mL (Normal range: 1.5-9.3)
FSH: 2.8 mIU/mL (Normal range: 1.6-8)
10/7/2016 while on Clomid for 8 weeks and on Opioids for 12 weeks and zero anastrozole
TT: 1,225 ng/dL (normal range: 250-827)
E2: 54 pg/mL (normal range: <39)
FT, LH and FSH were not taken due to my old doctor being retarded 
If you are going to stay on the opioid long term, I would do T-Cyp 100mg wk, HCG, and keep your dose of AI the same(maybe bump slightly). That will give you more ability to tweak your levels T/E2 levels.
If your opioid will be shorter term maybe do Nolvadex. You wonāt be able to tweak things nearly as much, but it will keep your HPTA going.
Will the T-Cyp 100mg wk negatively affect fertility? I assume T-Cyp stands for Testosterone cypionate, which sounds like it is real Testosterone replacement, which would affect fertility? Or is this fertility thing blown out of proportion?
Also, can Novaldex be used safely long-term (6-12 months)?
Any supplemental Testosterone will negatively affect fertility - which is why most guys need to come off temporarily to have kids. FSH / LH values will be important to keep track of to gauge fertility.
Regarding Nolvadex - generally it is harsher on the liver, while also lowering IGF-1 values so itās not used as a long-term solution.
To stay on the safe side, I will be taking Clomid 12.5mg EOD and also asking my doctor about combining it with a short term dose of Novaldex to kick start things. Maybe the 12.5mg EOD instead of the 25mg ED will allow my T to get where it needs to be without making my E2 skyrocket.
I had bad Clomid sides when I tried to run it at 50/day. Felt like garbage for 2 weeks. I just completed a restart protocol where I dosed at 25 EOD ā and then ultimately moving to 12.5 ED ā with no sides at all. I preferred the ED dosing. Will be posting bloods in my log when they come in.
Glad you found the sweet spot, Iām very curious what your labs look like. Iāll post mine in 6 weeks with the 12.5mg EOD
Also, what sides did you experience?
Just got my labs back and my total Testosterone was over 900 Ng/dl! Thatās awesome for such a low dose. Clomid works by really stimulating your pituitary and you donāt need a lot.
Clomid sides vary from anxiety, depression and brain fog as well as feeling very emotional since it targets your estrogen receptors in your brain, where as Nolvadex targets the estrogen receptors in breast tissue. This is why Nolvadex is best to treat/prevent Gyno.
TRT and fertility: Please see the stickies that I referred to earlier. hCG probably adequate. You can switch to a SERM now and then to introduce some pituitary LH+FSH. Check sperm counts and condition at times for confidence.
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Kindly if you recall, how was libido after 3wks no clomid + 0.25 EOD? Did it improve (more libido)? Thanks lots, because Iām in the same night-mare of a boat here,as of 13th Aug 2017. (Near the same situation as you in terms of Clomid protocol, respectably excluding the pain medication). If youāre still active here your wise voice would be highly appreciated. Thanks.
Good day sir,
Zero improvement in any area from clomid, including libido. It actually made me gain some weight. Skip it.
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@bbnoob25 thanks lots!
Did your estradiol (E2) figure come down after quitting Clomid?
&
Did you use Novaldex & an aromatase inhibitor instead? Cheers! 
E2 ended up coming down, but I was taking longer than I liked so I went on anastrozole to speed things up. I ended up going on testosterone +HcG + AI.
Thank you. I hope youāre doing great with your protocol.