I can’t even begin to describe the spikes I was getting from it. I didn’t realize what was going on until I switched back to cypionate.
The crazy thing is I didn’t even catch it the first time, just noticed I felt off. The second time around, I put 2 and 2 together.
Yeah I can imagine. That’s what I like about frequent injections with the long ester. No noticeable spikes really at all. Just feels constant.
Yes LH is secreted in pulses, but its not like in between the pulses there is no LH present in serum or within the testicles. Its more like an up and down.
If you inject hCG amounts which mimick physiological LH levels than no saturation or impact on LH sensitivity can be expected.
I think there is no any support for this theory
Agree. I’ve read nothing to confirm or refute the theory. It’s just a theory spread through the forums to help explain the nature of pulsatile LH secretion in terms that they can more easily relate to (their testicles).
There is an abundance of research and scholarly articles that clearly documents down-regulation of pituitary receptors to GnRH when exposed to constant stimulation. One would think that if testicular down-regulation was true, there would be an equal number of publications. If there are, I’d be thrilled to see them. I’m always open to furthering my understanding endocrinology.
In reality, it’s probably driven by the nervous system in the brain. More than likely the pituitary evolved to function in sync with the pulsatile release of GnRH from the brain. Pulsatility is a common phenomenon in the nervous system.
Please support this with documentation.
When doing prop…Did you adjust your dose for ester weight and higher peak? In my experience. If you are on 150/wk cyp. Then 130/wk for prop is the right dose. Part of that is ester and the rest is just trying to bring the peak down a bit. And prop should definitely be daily not eod. I think most people really underestate the amount the dose needs to be lowered with prop vs cyp. And it’s compounded if they try eod dosing because they get massive peaks.
I finally received quinagolide (another DA like cabergoline) from Canada and took a quarter tablet the last couple nights to see how I feel.
well it’s been subtle nausea, dizziness, and this mental fog. And worst of all, NO libido. It’s not placebo - caber always made music sound better, so I was convinced this weaker drug would do that and push my prolactin down just enough. I was dead set on success.
This is not unlike how cabergoline went for me. Made things worse.
Im shocked that 18mcg of quinagolide could bottom out my prolactin. Normal dose is 75-150.
anyone else have caber or bromo make things instantly worse? Already skating on thin sexual ice lately so I don’t really have a couple of months to try it and see if I adapt and improve.
I’d get your cortisol levels checked via 24-Hour Cortisol Saliva test.
DA decrease cortisol and will make you feel like garbage if you are having adrenal issues.
Forgot about this. I recently stopped two inhaled steroids and haven’t been feeling quite myself. Wonder if it’s related.
I’m considering giving it another 2 weeks and trying the DA again.
I’d give it more time. I’m sure once your body gets more used to it the experience will be different. Maybe not better but different.
Been noticing this the last couple of months since some libido issues began.
It reminds me of the pre-TRT days, when T spiked in the morning, and I’d want to have sex.
Last night, was out with the girl, and could barely get it up at all. 2 Cialis too. This morning? Springs to life!
What else could I be missing that “magically” happens in the morning?
Also it doesn’t always happen if I’m just tired in the evening (and usually I’m more tired just waking up).
Your night time erections are very important, your erections while sleeping repair and maintain your penis. This is one reason why men’s libido is higher in the morning because hormones regenerate while sleeping. In the evening you are tired and is need of rest, so naturally you are going to have a lower libido.
If you are not getting enough sleep, your libido will be affected.
Have you noticed any correlation to what you are eating? High fat meals can have a negative impact on erectile function.
I was wondering what the daily @bigmistake2 thread would be today lol. I don’t have an answer for this one but interested in what ends up fixing it.
Hmm might be the sleep then. Been doing better lately, but still not great. Good point.
Nothing yet! Been eating less lately though to try to lose a little weight. Not starving, but like 2k-3k cals a day.
I’m gonna start naming these daily thread with sequential numbers lol
Haha!
Do you take the Cialis daily?
What time of day do you take?
It may be you need to take it earlier in the day. Works faster on empty belly if not I’ve seen it take a few hours to work best.