Need Advice for High E2

Please post your normal numbers and ranges.

Have you looked at this? About the T Replacement Category - #2 by KSman

Most guys need around 1mg anastrozole per week when TT levels are 900-1000. But some are anastrozole over-responders who need 1/4th of the expected dose. You adjust the dose to get near E2=22pgml. This is E2 modulation, not elimination.

There is nothing wrong with TT=1000 when E2 is properly managed and hematocrit is OK.

Transdermals lead to more E2 than injections.

Google liquid anastrozole.

Some guys are testosterone hyper metabolizers and half-life is reduced. More T is needed and more often to get steady T levels. You will need steady T levels for anastrozole to work properly.