Maybe the thyroid issue is something simple like not using iodized salt.
TSH should be closer to 1.0
T3, fT3, T4, fT4 should be near mid range.
Please see links found here: About the T Replacement Category - #2 by KSman
advice for new guys
things that damage your hormones
protocol for injections
thyroid basics explained
What were units for the sex hormone panel?
Blood work or saliva testing?
see: Sex hormone-binding globulin - Wikipedia
TT consists of:
FT
T+SHBG
T+albumin
Bio_T is FT + T+albumin
T+SHBG is not bio active.
FT says that your T levels could be better
lab work for bio_T would be a good input
Estrogens increase SHBG production in the liver and T decreases it.
Anastrozole is expected to decrease E2 and SHBG.
With less T and decreasing E2, you may feel better as E2 opposes what T does.