[quote]Bill Roberts wrote:
[quote]mertdawg wrote:
I will post references if people promise to read them, but I didn’t say 150 gram protein limit. I said that about half of the protein most people eat converts to glucose over a period of 3-6 hours, and that the proportion rises to 100% by about .85 grams per pound of bodyweight.
[/quote]
Not disagreeing with your general point as to protein having some action as a slow release source of glucose, but on that numeric value, fully 100% wouldn’t be possible due to leucine and lysine being non-glucogenic and being roughly 20% of proteins (varies of course) as well as some conversion to ketone bodies and I suppose some going to turnover, with the replaced amino acids not necessarily converted to glucose. I haven’t seen 100% in the literature but don’t recall any specific figure that I have seen.
As a practical bb’ing observation, protein intake can be used to balance some amounts of Humulin R injection (so far as I know discovered by Oliver Starr, tried by myself with some success) but not at 1:1 relative to carbs. So that would speak against conversion being anything close to 100%.
Also as practical observation, not my own but of others, for diabetics daily protein intake doesn’t cause nearly as much need for insulin injection, at least not according to any calculation method I know of or the few personal accounts I’ve learned, as does daily carbohydrate intake.[/quote]
Thanks, I wrote 50-60% because that is common advice for diabetecs. Keep in mind as well that even if it is at 50% it doesn’t mean that 20 grams of protein requires as much insulin as 10 grams of carbs, because its released slower and the brain will use 100 grams a day without insulin and the muscles will use some, and I also think some is used in digestion without the need for insulin.
So 20 units of carbs in 2 hours may require insulin while 20 units of net carbs in 4 hours might not require any insulin.
What does leucine and lysine end up turning into? (Acetyl CoA?)
The BCAAs are anticatabolic and I have read the leucine can cause insulin secretion which means that it will tax the pancreas and the more insulin you release in the day the less sensitive you become, so leucine may have a mechanism if increasing insulin resistance in high doses even if it isn’t turned to glucose.
In fact most AA’s are insulinogenic and so the more you take the more you release and the less sensitive you may become both short term and potentially long term.
The most recent research I read, and I am looking for suggests that high protein intake raises fasting blood sugar primarily because it slightly lowers insulin sensitivity which IS BASICALLY the issue presented in this thread.
Another issue is that having full liver glycogen reduces insulin sensitivity or at least hepatic insulin sensitivity.
I am open to debate on this and I don’t want to recommend anything to anyone-people need to think for themselves-but if someone is insulin resistant and they were eating 320 grams of protein a day that might be a factor.
What CAN protein possibly turn into to be burned as fuel? Which of those products do not pass through glucose of g6p on the way?