Yes, it seems that lowering your TM would be wise.
I am not sure what you are asking, but here is an attempt to address your question. Generally one would plan out a set of leaders and anchors, most commonly 2 leaders and one anchor. You make sure the TM is no more than 85% before the first leader, and otherwise you just add the 5-10 lbs at the end of each cycle until the anchor is done.
You an use normal 5/3/1 PR sets in a leader. If you are doing that, you would still start with the same sort of 85% TM at the beginning. Wendler has a few programs that include PR sets in the leaders in 5/3/1 Forever, so I highly recommend that you get and read that book. But, in general, yes you can use an original 5/3/1 style with PR sets in the anchor, and you would still use a no-more-than 85% TM for that.
Regarding “if I don’t go overboard with the prs,” I think it is more not going overboard on everything else. If you do 5’s PRO, then you can do more supplemental work (like Boring But Big), but if you are pushing for PRs something needs to be lessened, such as by keeping supplemental work to just 5x5 First Set Last