Agree on the garbage comment !
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I am in the medical field. Are you offering me a dream job? @physioLojik LOL
Colorado too? Iām down!!!
What do you do? Perhaps. @anon10035199
Non-Registered Nurse, for now. LPN @physioLojik
@anon10035199 @physioLojik Since you are in here getting my hopes up with all the emailsā¦ you can work out the kinks with me as the test subject.
Iām extremely honored that you would say something like that, joking or not. The job I am at now though, I can retire before Iām 45, so I may stick around.
However, that being said, the agency I work for, may not be around for too much longer if things keep going they way they are.
@lowtengineer Definitely need an SHBG. Gives us a better idea of how many free hormones you got floating around. Also, what is your diet like? Have you tried increasing some cruciferous veggies like Broccoli?
@anon10035199 My test for free testosterone was a calculated value so the SHBG was obtained for that but its hidden from me in the patient portal. I was told on the phone that it is 25 but I donāt for sure know a range. I know it used ARUP laboratory and from their website it looks like their range is 11-80 nmol/L.
I do eat broccoli and cauliflower every day for lunch. Usually about 8 decent sized florets of each. I try to limit sugars and refined carbs but they still make it to my food hole. I really need to buckle down and cut out the cookies and shit. Typically an average day I eat 140g protein, 80g fat, and 300g carbs.
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I prefer to run direct Free T when on TRT, not a huge fan of calculated. Itās nice to compare both side by side though.
And right now you are injecting 90 every 3.5 days? is that correct still?
#1 most manageable variable would be controlling your weight. Aromatase is made in fat cells.
At my next labs I was going to ask my doctor to do the test that measures free t instead of calculate. I thought I read somewhere that the test for measuring free t isnāt very accurate so I havenāt pushed it.
I have been doing 60mg 3x weekly for 3 weeks now.
I wonder if there is a body fat percentage or a certain lbs of excess fat that is typically acceptable to not have negative impacts. Or do you have to be ripped to be optimized?
Ok bro. You only need to inject twice a week.
So 180mg a week is too much for you. Your having e2 symptoms. So the best way to go would be to slowly lower your dose until your e2 symptoms subside.
You COULD try 75 twice a week for total of 150, but thatās still kinda highā¦ I would go with 60 twice a week. Thatās 120mg. see how you feel, get labs, and go from there.
Basically you want to find that balance. You want to be RIGHT below wherever is causing you symptoms. Thatās the sweet spot.
I know its counterintuitive to ālowerā your dose, thinking you will feel worse, but this isnāt the case. You need to find that balance. Sometimes it takes a little while.
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@anon10035199 Iām 3-4 weeks into this protocol so Iām going to ride this one out to week 8 to get labs and see where its at. Right now Iām doing Wed morning, fri evening, and sun night to try and get it spread out evenly. Iām a big fan of consistency and this is anything but consistent. For that reason I wonder if EOD would be easier for me to either be a shot day or not. When I was doing e3.5d it was the wrong dose so it did feel like the timing of the shots was bad but maybe just because the dose was wrong.
I canāt really explain the feeling, but right now it always feels like Iām ready for the next shot when its time. Of course I know nothing actually changes immediately at shot time.
Funny you mention the 75mg e3.5d. When my doctor first upped my dose from 100 to 150 I tried for 3 weeks splitting it in half but I felt like shit those weeks. I didnāt realize at that time that any dosing or protocol change would make me feel crappy, so I changed to what my doc said 150mg e7d. Ever since then Iāve wondered in the back of my mind if the 75mg e3.5d was already too high but I didnāt get labs nor would I have even gotten the correct ones to find out.
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I have new labs to update. I have a cmp and cbc panel but didnāt type them all in. Labs were taken after 9 weeks of being on 3x a week:
60mg test cyp
300iu hcg
0.125mg anastrozole
500mg metformin 2x daily
iron supplement
I try to spread the injections evenly so I do wednesday morning, friday evening, sun night. I hate the inconsistent schedule timing. I feel like I would like the consistency for my routine to do EOD. Maybe this would help reduce the peak e2 enough to get rid of the AI.
I still donāt feel great after 9 weeks of this change. I think the ups and downs that I was experiencing have gone away. Now I just sometimes have a feeling of tiredness. Libido is pretty low. Recently my joints mostly knees/legs are sore. I hurt my back maybe 5 months ago so my deadlift/squatting has been very minimal and I do no running.
I donāt have an appointment scheduled with Defy yet. Does anyone have any suggestions or ideas for things I should discuss with them?
| labs | range | 60mg 3x/wk |
|---|---|---|
| labs date | 9/19/2018 | |
| lab timing | trough | |
| total test | 240-950 ng/dl | 1020 |
| free test | 4.85-19 pg/ml | 34.7 |
| bioavailable test | 72-235 | 541 |
| estradiol enhanced (LC/MS) | 10-40 pg/ml | 42 |
| esterone | 10-60 pg/ml | 43 |
| Hct | 42-52 % | 48 |
| fasting glucose | 70-105 mg/dl | 107 |
| Iron | 50-212 ng/dl | 101 |
| Iron Satn | 27 | |
| Iron + TIBC | 250-450 | 373 |
| Ferritin | 23.9-336.2 ng/ml | 48 |
| DHEA-S | 89-457 ug/dl | 404 |
Completely fasted for 12 hours?
Yeah I was fasting. haha maybe it was 11 hrs fasting but yes it was close to 12hrs fasted.
Your fasting glucose is high. Maybe get that tested again? Could be a lab error.
It doesnāt seem like a lab error. Its consistent with all of my past tests. They are all up in the table in the top post. Itās the reason defy suggested the metformin. I have some past a1c results of 5.1 and 5.3. My GP doctor keeps telling me diabetes is not a concern. Is there additional testing I should do? I already try to eat decent, limit sugars, drink only water, and try to have a small desert once a week instead of every day.
You need to reduce the dosage when injecting more frequently or levels will be insane, minimum 20% reduction everytime you move injections closer together.
Are you saying they currently are insane? Or if I want to go to eod that they would become insane without a reduction?