It’s nice to feel better, but still don’t know WHY my E2 is so fucking high and why my body is pumping out so much test. Time will tell. I know I will get everything sorted because I’m so determined, I never give up.
How long did you take 1mg a week for? Is that the sensitive test. You really can either 1) do what I did and crash or go low like 4 times by lowering your dose each time you find out it’s taking you too low or 2) be smarter than me and start off with a lower dose and blood test - because you can always take more arimidex.
I vote number 2 How much are you planning to try taking? I found the whole dropper thing so annoying, I’m glad I am just emptying my 0.125mg caps into the vodka. I personally think the dropper - even if it is graduated is inaccurate. I draw with a syringe perfectly 1ml, then I see that my test tube has been reduced by 1ml. Perfect or near perfect dose every time.
Hey. It only took 3.25mg of Arimidex over 3 doses for me to feel like shit and have my E2 crash to 8.4.
I’m definitely going with option 2 - I will reintroduce arimidex when necessary, based on blood tests and feel. At this point I’m getting labs every 2 weeks and will continue to do so until I’m dialed in. My plan is to start with 0.05mg, which is easy to measure on my dropper. I would much rather have high E2 and be able to quickly bring it down with arimidex rather than having low E2 and waiting for levels to come back. It has been 8 days now since I last had AI and I’m slowly starting to feel better.
Hey hostile if you’re still around or anyone else would be able to answer this I have a quick question…
Does anyone see any issues with dissolving 0.5mg pill into 5ml vodka? It seems like a lot of vodka for such a small amount, but this is the only way I could accurately draw up 0.05mg by drawing up 0.5ml in a syringe.
My droppers aren’t graduated and I wanna avoid those if possible.
I’ve never dissolved that small of an amount. I dissolve 5 mg in 5 ml. Then I use a dropper containing the vodka anastrazole solution and count how many drop it takes to fill 1 ml. Then using math I calculate my dosage since I know 1 ml = 1 mg.
So if it takes 20 drops to get to the 1 ml marker, I know 1 drop would be 0.05 mg since 1/20 = 0.05.
Thanks. I’m thinking of stopping the Arimidex for about a month - I can’t get it right and I’m constantly crashing no matter what I do.
I see my doctor early March and want to ask for Aromasin instead. Does anyone know if you are an Arimidex over responder you’ll also be an Aromasin over responder? Is that how it works?
Aromasin may be more effective for you because many take upwards of 25 mg per day, which would mean you could hypothetically dose extremely low amounts with it.
"Arimidex (Anastrozole) is a selective, nonsteroidal aromatase inhibitor so it a competitive aromatase inhibitor. The key to this med is how it achieves the aromatase inhibition. Arimidex is a REVERSIBLE antagonist that binds to the aromatase enzyme. In simple terms arimidex will bind to aromatse preventing the conversion of testosterone to estrogen but after X amount of time it will unbind and testosterone will be able to be converted to estrogen. So while you are taking the med you will have lower estrogen levels but you need to keep taking it. Anastrozole does causes an 85% decrease in estrone sulfate levels. Just because you have lower estrogen levels do not mean that you can not get gynecomastia it will just reduce the chances.
Here are some key points:
-Onset of estradiol reduction: 70% reduction after 24 hours; 80% after 2 weeks therapy
-Duration of estradiol reduction: 6 days
-Absorption: Well absorbed; extent of absorption not affected by food
-Half-life elimination: ~50 hours
-Time to peak, plasma: ~2 hours without food; 5 hours with food
Aromasin (Exemestane) is an IRREVERSIBLE steroidal aromatase inactivator. That is it irreversibly blocks the active site of the aromatase enzyme for the life of the enzyme, leading to inactivation (8220;suicide inhibition8221 and thus preventing conversion of androgens to estrogens in peripheral tissues. Remember that your body will produce more aromatase enzymes.
Some more key points
-Absorption: Rapid and moderate (~42%) following oral administration; absorption increases ~40% following high-fat meal
-Half-life elimination: 24 hours
-Time to peak: Women with breast cancer: 1.2 hours"
How much are you planning to try taking? I found the whole dropper thing so annoying, I’m glad I am just emptying my 0.125mg caps into the vodka. I personally think the dropper - even if it is graduated is inaccurate. I draw with a syringe perfectly 1ml, then I see that my test tube has been reduced by 1ml. Perfect or near perfect dose every time.