You seem to be skirting around the thyroid, iodine, iodized salt and body temperature issues. Please post oral body temperatures as per the thyroid basics sticky.
You sometimes have felt cold more than made sense?
Outer eyebrows sparse?
There is not enough iodine in food, that is why salt has been iodized for almost 100 years.
Typically we see that guys need near 1mg anastrozole for every 100mg T ester. If E2 goes to low, you can have a lot of negative effects.
Please read these stickies found here: About the T Replacement Category - #2 by KSman
- advice for new guys
- things that damage your hormones
- protocol for injections
- thyroid basics
- finding a TRT doc
Anastrozole serum levels need to match T levels and that is not going to work right with the changing levels of T from injecting once a week. Suggest that you self inject twice a week and take anastrozole at time of injections.
Your weight gain could easily be increased by low thyroid function. The symptoms of low thyroid function and low-T are largely the same. If thyroid function is low, you can still have significant issues while on TRT, including lethargy and mood/depression issues.