I will get my new bloodwork under the increase in 2 weeks.
About the T to E ratio:
I calculated my free T for the last bloodwork (with Albumin and SHBG)
Free testosterone: 0.054 [µg/l]
Free testosterone: 1.78[%]
bioavailable testosterone: 1,291 [µg/l].
bioavailable testosterone: 42.61 [%]
These values are not so bad after all? What do you say?
FreeT is 5.4 ng/dL that’s very low, needs to at least double.
I found this study:
Thyroid hormone is known to affect sex hormone-binding hormonal globulin (SHBG) concentrations. Men with hyperthyroidism have elevated concentrations of testosterone and SHBG. Thyroid hormone therapy in normal men may also duplicate this elevation. In addition estradiol elevations are observed in men with hyperthyroidism, and gynecomastia is common in them as well. In contrast to patients with primary hypothyroidism, men with hyperthyroidism exhibit hyperresponsiveness of LH to GnRH administration and subnormal responses to hCG.
I have morning temperatures of only 36°C (96,8 Fahrenheit), ft3/ft4 completly low as you can see in this thread…
Now somebody please tell me there’s no correlation?
Thyroid experts here have appointments with at least 3 months waiting time. What am I going to do? I hope 50 mmc L-thyroxine will solve the problem.
Blood work comes in 1 week.
Quick update:
Testosteron: 452 ng/dl
E2: 26 pg/ml (>40)
Thats on 1000 I.U (I.E.) EOD. 2 weeks on that protokol.
I think Im on a good way so far.
TSH: 1.7
fT3: 2.03 pg/ml (2-4)
fT4: 1.06 ng/dl (0.9-2)
Thyroid still fucked up under 37.5 mmc L-Thyroxin, now on 50 mmc L-Tyroxin, have to wait 6 weeks…
Any advice?
Best Regards
How do you feel?
Depending on how you feel you could move up slight with hCG. But it generally seems your testicles are rather unresponsive to stimulation by hCG.
Move your LT4 up to 50 and then 2 weeks later to 75 mcg. Typical LT4 doses are between 75 and 150 mcg. On 37.5 mcg you are still borderline hypothyroid, that’s way too low.
Mine are also but they respond with a lot of e2 as well…that is not causing me issues so far
To be honest, I feel much better since the increase, more hair growth, finally a good night boner again, libido is back, no more night sweats
but dry and cold hands, tiredness is still present, but that is probably the thyroid gland
→ LT4 I will increase, but I think rather slower than you suggest. At least my doc said to take it slow. (in 6 weeks steps)
→ Now I’m really not sure if I should raise hcg any more, advices?
If you feel good than there is no need for an increase.
Do you know your SHBG level?
Regarding LT4; there is little risk that you slide into hyperthyroidism if you increase faster to 75 mcg, but just follow your physician’s instruction.
Okay, I´ll keep this protkol
We will see how my condition and blood work changes. Got a new one every six weeks.
It should only be temporary, I will get FSH soon and when I am fertile I will switch to TRT. Of course when the swimmers are frozen.
SHBG: 35 nmol/l → FAI around 45…
Thanks for the advice johann77 !
Update:
Good morning everyone,
hope you are all fine during this “corona” issue…
My labs on mid of february were fine, a little bit better than 1 month bevor.
Vitamin D3 → very good (55ng/ml in winter times)
magnesium, zinc, copper, selenium, iodine, iron (also transferrin saturation), all top, LDL, HDL, morning cortisol was good (160 ng/ml), DHEA was good, all good…
I got the latest labs and I think I have now a major problem here:
My ft3 crashed on 75mcg L-Thyroxin:
FT 3 pmol/l(2,7-6,9) 2,2
FT 4 pmol/l(10,0-28,0) 14,0
TSH μU/ml(0,20-2,00) 0,84
T-levels also lower:
Testosteron: 242 ng/dl
E2: 19,4 pg/ml (>40)
SHBG nmol/l(9,0-55,0) 34,5
FAI around dropped to 24
My doc wanted to make a ACTH-Test/CRF-Test:
26.03.20 ACTH pg/ml 0-80 34
26.03.20 ACTHi 15 pg/ml 40,9
26.03.20 ACTHi 30 pg/ml 41,9
26.03.20 ACTHi 45 pg/ml 32,9
26.03.20 ACTHi 60 pg/ml 30,2
26.03.20 Cortisol μg/dl 2,0-25,0 16,3
26.03.20 Corti 15 μg/dl 15,80
26.03.20 Corti 30 μg/dl 16,60
26.03.20 Corti 45(Dex) μg/dl 16,00
26.03.20 Corti 60 μg/dl 15,80
→ Insufficient cortisol rise in the CRF test. Thus, a hydrocortisone substitution with 10
mg in the morning and 5 mg at noon.
I honestly don’t know what to think about it because I’m actually doing pretty well. Why should I suddenly have a pituitary insufficiency (E23.0)?
Regarding the ft3/ft4 : I accidentally took my L-thyroxine in the morning of that test + regarding corti: the test was in the afternoon, so cortisol is lower anyway?
Should I just ignore that and keep going? What do you think?
Next bloodwork in 3 weeks, would do you think? I´m still on 750 hcg every other day. FSH starts in 2 weeks …
What a pity that no one has been able to answer me yet. :-\
i found out something else: My endocrinologist measured the hcg level in the blood (serum).
ß-HCG mU/ml (0.0-5.0) 63.2
LH mIU/ml (0,5-6,0)
Since it is an LH analog. Is there any way to convert this? Theoretically the value is skyrocket or not?
Best Regards
Hello guys,
I changed nothing on my protocol: (750 I.E. Hcg eod, 75 mcg L-Thyroxin)
FT 3 pmol/l(2,7-6,9) 3
FT 4 pmol/l(10,0-28,0) 13,5
TSH μU/ml(0,20-2,00) 1,2
Testosteron nmol/l (6,2-26,2) 12,7
Testosteron ng/dl 366
20.04.20 SHBG nmol/l(9,0-55,0) 28,0
20.04.20 IGF1 ng/ml(120,0-190,0) 152,0
20.04.20 freier Androgenindex (Free Androgen Index FAI)(15-90) 45
20.04.20 Dihydrotestosteron pg/ml(250,0-990) 251,0
Do you know why my DHT is so low?
20.04.20 DHEA-S μg/dl(80,0-300) 402,0
20.04.20 Estradiol pg/ml(0,0-36,0) 24,6
I’m actually doing pretty well and received FSH from my doc. → 3x 150 I.E. per week.
I will also raise my L-Thyroxin to 100 mcg.
I hope in 60 days the spermiogram tells me something good and I can switch to real TRT.
Comments and recommendations are welcome !
Best Regards
Update: 400 I.E. HCG ED, 150mmc L-Thyroxine
Testosteron ng/dl 473
SHBG 31 nmol/l
FAI: 52 (15-90)
E2: 29 (0-36)
FSH: 4.5 mIU/ml (1.5-20)
DHT 259 pg/ml (250,0-990)
Do you know why my DHT is so low? Any advices?
I think it looks good otherwise. On Monday, I have an appointment on the cryopreservation of my sperm.
Does exogen FSH surpesses the HPTA or can i try restart the HPTA with Clomid and add the FSH to hold the spermatogenesis? I dont want the waste that very expensive stuff.
If that doesn’t work. Which TRT would you recommend (also because of low DHT)? With Nebido I made bad experiences.