How Much Does Glutamine Help?

[Smitty88]

[quote]sasquatch wrote:
I have neither the time or inclination to peruse the internet for studies and doctors who believe in glutamine supplementation. I’m quite certain I can match anything you can find with a google search. Good day. [/quote]

lol

[vroom]

[quote]Smitty88 wrote:
Extra glutamine will do no more for you than an extra dose of any other amino acid.

Do you like that better?[/quote]

Well, when you put it that way, did you know that there are apparent effects caused by taking some amino acids on their own?

Anyway, I think you are missing the idea that people aren’t just talking about muscle gains.

[jsbrook]

[quote]Smitty88 wrote:
yorik wrote:
But since I know I’m right…

Do you really believe that the world only exists inside the power rack?

At least qualify your statement.

Try this…“Glutamine is totally worthless as a performance enhancing supplement.” We all agree. No debate there.

Extra glutamine will do no more for you than an extra dose of any other amino acid.

Do you like that better?[/quote]

Yeah. Not like BCAAs aren’t beneficial. Riight…

[BarneyFife]

How about picking up some glutamine, trying it, and seeing if you like it. If it doesn’t seem to have any effect, then ditch it.

And for those of you that say “not all supplements you can feel”, if you don’t notice at least some difference with a supplement, you probably don’t need it.

Greens plus doesn’t help me to lift anvils overhead by the horn, and it doesn’t help me to leap tall buildings either. But it DOES turn my sht green. Thats how I know its working.

And as far as multi vitamins and fish oil goes, take them for a month, and then quit taking them. Feel worse for the wear? then you know they are working.

Maybe I have bad opinions, but unless I notice an effect, I assume a supplement is junk.

[sasquatch]

[quote]BarneyFife wrote:
How about picking up some glutamine, trying it, and seeing if you like it. If it doesn’t seem to have any effect, then ditch it.

And for those of you that say “not all supplements you can feel”, if you don’t notice at least some difference with a supplement, you probably don’t need it.

Greens plus doesn’t help me to lift anvils overhead by the horn, and it doesn’t help me to leap tall buildings either. But it DOES turn my sht green. Thats how I know its working.

And as far as multi vitamins and fish oil goes, take them for a month, and then quit taking them. Feel worse for the wear? then you know they are working.

Maybe I have bad opinions, but unless I notice an effect, I assume a supplement is junk. [/quote]

Overall----

pretty bad advice.

But, asparagus does make my pee stink so it must be working.

[Smitty88]

[quote]vroom wrote:

Anyway, I think you are missing the idea that people aren’t just talking about muscle gains.[/quote]

No, I get it. Extra doses of glutamine are worthless for muscle building, enhancing the immune system of a healthy individual and just about anything else that you can think of.

[Smitty88]

Oh wait, I think I’m wrong on the glutamine is worthless argument. It has great financial enhancing powers for those who sell it.

Remember Vanadal Sulfate? Enought said.

[vroom]

[quote]Smitty88 wrote:
Oh wait, I think I’m wrong on the glutamine is worthless argument. It has great financial enhancing powers for those who sell it.

Remember Vanadal Sulfate? Enought said.[/quote]

Well, tell you what, why don’t you explain why the journal article I posted earlier wouldn’t be interesting to anyone… ?

[yorik]

He just doesn’t get it. No sense arguing.

[Smitty88]

[quote]vroom wrote:
Smitty88 wrote:
Oh wait, I think I’m wrong on the glutamine is worthless argument. It has great financial enhancing powers for those who sell it.

Remember Vanadal Sulfate? Enought said.

Well, tell you what, why don’t you explain why the journal article I posted earlier wouldn’t be interesting to anyone… ?[/quote]

It is interesting. And there will always be conflicting reports. There were also reports that Vanadal Sulfate worked wonders. Some reports that is.

[Smitty88]

[quote]yorik wrote:
He just doesn’t get it. No sense arguing.[/quote]

No, YOU don’t get it! Now show me the data where it has been conclusively proven that glutamine does what the manufacturers say.

[sasquatch]

[quote]Smitty88 wrote:
yorik wrote:
He just doesn’t get it. No sense arguing.

No, YOU don’t get it! Now show me the data where it has been conclusively proven that glutamine does what the manufacturers say.[/quote]

Nothing can be conclusively proven true.

My studies that show it works would be as useful to you as your studies of uselessness are to me. Give it a rest

[anon37909890]

It was really cheap at Vitamin Shoppe and I put it in my PWO. Dont know if it benefits me but its cheap enough now to not really worry about it.

[buffalokilla]

[quote]Smitty88 wrote:
"Effect of glutamine supplementation combined with resistance training in young adults.

Candow DG, Chilibeck PD, Burke DG, Davison KS, Smith-Palmer T.

College of Kinesiology, University of Saskatchewan, Saskatoon, Canada.
during 6 weeks of total body resistance training
[/quote]

The conclusion for this study was ridiculously inappropriate. If you threw college aged guys on half a gram of test for 6 weeks you probably wouldn’t see a statistically significant difference. It really shows nothing about anything, other than people get a little stronger after 6 weeks.

"J Strength Cond Res 2002 Feb;16(1):157-60
The effects of high-dose glutamine ingestion on weightlifting performance

Antonio J, Sanders MS, Kalman D, Woodgate D, Street C.

Sports Science Laboratory, University of Delaware, Newark, Delaware 19716, USA.

The purpose of this study was to determine if high-dose glutamine ingestion affected weightlifting performance. In a double-blind, placebo-controlled, crossover study, 6 resistance-trained men (mean +/- SE: age, 21.5 +/- 0.3 years; weight, 76.5 +/- 2.8 kg(-1)) performed weightlifting exercises after the ingestion of glutamine or glycine (0.3 g x kg(-1)) mixed with calorie-free fruit juice or placebo (calorie-free fruit juice only). Each subject underwent each of the 3 treatments in a randomized order. One hour after ingestion, subjects performed 4 total sets of exercise to momentary muscular failure (2 sets of leg presses at 200% of body weight, 2 sets of bench presses at 100% of body weight). There were no differences in the average number of maximal repetitions performed in the leg press or bench press exercises among the 3 groups. These data indicate that the short-term ingestion of glutamine does not enhance weightlifting performance in resistance-trained men."

Um, okay. Pretty much nothing taken orally directly before lifting will do anything significant. The conclusion was appropriate, though. I’m not sure why you posted this abstract really.

"Metabolism 2000 Dec;49(12):1555-60 Related Articles, Links

Intravenous glutamine does not stimulate mixed muscle protein synthesis in healthy young men and women.

Zachwieja JJ, Witt TL, Yarasheski KE.

Exercise and Nutrition Program, Pennington Biomedical Research Center, Baton Rouge, LA, USA.

We investigated the effects of a glutamine-supplemented amino acid mixture on vastus lateralis muscle protein synthesis rate in healthy young men and women. Three men and 3 women (27.8 +/- 2.0 yr, 22.2 +/- 1.0 body mass index [BMI], 56.1 +/- 4.5 kg lean body mass [LBM]) received a 14-hour primed, constant intravenous infusion of L[1-13C]leucine to evaluate the fractional rate of mixed muscle protein synthesis. In addition to tracer administration, a clinically relevant amino acid mixture supplemented with either glutamine or glycine in amounts isonitrogenous to glutamine, was infused. Amino acid mixtures were infused on separate occasions in random order at a rate of 0.04 g/kg/h (glutamine at approximately 0.01 g/kg/h) with at least 2 weeks between treatment. For 2 days before and on the day of an infusion, dietary intake was controlled so that each subject received 1.5 g protein/kg/d. Compared with our previous report in the postabsorptive state, amino acid infusion increased the fractional rate of mixed muscle protein synthesis by 48% (P < .05); however, the addition of glutamine to the amino acid mixture did not further elevate muscle protein synthesis rate (ie, 0.071% +/- 0.008%/h for amino acids + glutamine v 0.060% +/- 0.008%/h for amino acids + glycine; P = .316). Plasma glutamine concentrations were higher (P < .05) during the glutamine-supplemented infusion, but free intramuscular glutamine levels were not increased (P = .363). Both plasma and free intramuscular glycine levels were increased when extra glycine was included in the infused amino acid mixture (both P < .0001). We conclude that intravenous infusion of amino acids increases the fractional rate of mixed muscle protein synthesis, but addition of glutamine to the amino acid mixture does not further stimulate muscle protein synthesis rate in healthy young men and women."

Um. Again, this isn’t really appropriate to resistance training individuals over the long term. This study basically says “More food without a stimulus won’t make you build more muscle.” Useful for sedentary patients who may be experiencing muscle wasting, but not for us.

I don’t really know enough about immunity to comment on the rest.

-Dan

[Smitty88]

[quote]sasquatch wrote:
Smitty88 wrote:
yorik wrote:
He just doesn’t get it. No sense arguing.

No, YOU don’t get it! Now show me the data where it has been conclusively proven that glutamine does what the manufacturers say.

Nothing can be conclusively proven true.

My studies that show it works would be as useful to you as your studies of uselessness are to me. Give it a rest[/quote]

Okay, that’s it.

I am now telling you for the last time to stop using glutamine.

Got it?

Don’t make me raise my voice.

[yorik]

[quote]Smitty88 wrote:
yorik wrote:
He just doesn’t get it. No sense arguing.

No, YOU don’t get it! Now show me the data where it has been conclusively proven that glutamine does what the manufacturers say.[/quote]

Your entire universe revolves around the gym, and everybody agrees glutamine does not help there.

Listen to yourself…“Hey you! Are you dying of cancer? Does your oncologist tell you to take glutamine? DON’T DO IT. Glutamine is TOTALLY worthless.”

Do you get it now?

No? Here are some more for you…

Water does absolutely nothing for building muscle, SO STOP DRINKING WATER. IT’S TOTALLY WORTHLESS!

Motor oil does absolutely nothing for building muscle, SO STOP BUYING MOTOR OIL. IT’S TOTALLY WORTHLESS!

Does anybody else get it?

[folly]

I’ve found that when I am in a high rep cycle, 15-20g/day helps boost my recovery and decrease DOMS, which I get really bad with higher reps or while dieting.

I generally don’t take it while bulking, except what is included in Surge.

By the way, n=1.

-folly