It has been 5 days since I finished Prometrium 200mg (10 day pack) and my period still didnt come back. What possible causes can prevent to not to bleed. So flustruated.
[quote]florida2001 wrote:
It has been 5 days since I finished Prometrium 200mg (10 day pack) and my period still didnt come back. What possible causes can prevent to not to bleed. So flustruated.[/quote]
You need to discuss with an MD the possibility that you have secondary amenorrhea owing to subclinical exogenous hyperthyroidism. In your zeal to preclude weight gain, it seems you may have drastically over-medicated yourself with respect to thyroid-hormone supplementation (your TSH level is a FULL ORDER OF MAGNITUDE BELOW the lower limit of normal).
Hi,
I think TSH is suppressed because I’m on thyroid medication, my freeT4 and freeT3 are both in normal range. I will discuss it with doctor. thx
[quote]florida2001 wrote:
Hi,
I think TSH is suppressed because I’m on thyroid medication, my freeT4 and freeT3 are both in normal range. I will discuss it with doctor. thx[/quote]
From Update on Subclinical Hyperthyroidism:
“Subclinical hyperthyroidism is defined by low or undetectable serum thyroid-stimulating hormone (TSH) levels, with normal free thyroxine (T4) and total or free triiodothyronine (T3) levels. Currently used third-generation assays are capable of detecting TSH at levels as low as 0.01 to 0.02 mIU per L. Subclinical hyperthyroidism can be divided into two categories: low but detectable TSH levels (0.1 to 0.4 mIU per L), and suppressed TSH levels (less than 0.1 mIU per L).”
From Evaluation of Amenorrhea:
“In those with a low TSH and a normal free T4 level, serum tri-iodothyronine (T3) should be measured; an elevated T3 can identify hyperthyroidism that otherwise might escape detection.”
[Note that your FT3 is elevated]
yes my free t3 are elevated bc Im on 25 mg cytomel and 100mcg synthroid, I actually had period when my synthroid was much higer(125-150mg), what happend, the doctor had been lowering the dosage slowly over the last year and my peridod disappeared when I was on the dosage I’m now (100mg synthroid and 25 mcg cytomel). I have always been on the same dosage of cytomel.
I’m just trying figure out, because I’m not sure that the problem is thyroid in this point. I used to get off the thyroid medication and I couldn’t function. What is interesting that no matter what dosage I was on, with synthroid only or combination of cytomel my TSH was always supressed. That is what is more challenging.
Consider getting evaluated by a reproductive endocrinologist. You can find one near you via their website:
thank you,
TSH levels that are very low are OK in many cases when dosing is driven by other criteria.
Too much progesterone can turn off your HPOA and then estrogen levels drop and the lining of your womb does not become spongy with blood, and you don’t ovulate. I am thinking that E2 levels were too low. However, your hormone system can have other issues too.
Please revisit my posts re body temperatures and rT3. You can use body temps to adjust your thyroid Rx dose. However, that will not work well if rT3 is messing things up and more T4 then will create more rT4 and you don’t get better.
rT3=20 may be bad for you. If you increase T4, rT3 will be worse. I think that thyroid issues may be a big factor in the problems with your cycles. You need to explore options to get rT3 down and fT3 up to get normal body temperatures. And I pointed out that as rT3 levels drop, your thyroid meds will need to be reduced as there could be too much rT3 getting into the cells. Please adopt the notion that your body temperatures are important.
[quote]KSman wrote:
TSH levels that are very low are OK in many cases when dosing is driven by other criteria.
Too much progesterone can turn off your HPOA and then estrogen levels drop and the lining of your womb does not become spongy with blood, and you don’t ovulate. I am thinking that E2 levels were too low. However, your hormone system can have other issues too.
Please revisit my posts re body temperatures and rT3. You can use body temps to adjust your thyroid Rx dose. However, that will not work well if rT3 is messing things up and more T4 then will create more rT4 and you don’t get better.
rT3=20 may be bad for you. If you increase T4, rT3 will be worse. I think that thyroid issues may be a big factor in the problems with your cycles. You need to explore options to get rT3 down and fT3 up to get normal body temperatures. And I pointed out that as rT3 levels drop, your thyroid meds will need to be reduced as there could be too much rT3 getting into the cells. Please adopt the notion that your body temperatures are important.[/quote]
I do think the same, my estradiol may be really low, so that progesterone did not induced bleeding. Last test came out estradiol 40 and progesterone 0.5. So I am thinking my estradiol should be littel bit higer or something just simply messing a whole cycle out.
I read the “wilson temperature” book. My temperature is in the morning between 97.3-97.7 and get higer in the afternoon 98.1-98.6. It may be sign of adrenal dysfunction.
I will talk to a doctor about my options and I agree, raising up T4 dosage wuldn’t help. I have been there already. I think the best bet wuld be lower t4 littel bit and up cytomel slightly.
I also started breaking out on my face after I finished Progesterone. 
thx
I also started breaking out on my face after I finished Progesterone.
This suggests that progesterone may have shutdown your HPOA and now it is rebounding. A good sign in a way.
Spoke to doctor, she said sometimes it takes weeks to restart cycle after progesterone .Still waiting
Keep the HPOA shutdown issues in mind and dealing with that would require less progesterone.
Hi, I just got back my saliva cortisol diurnal test result (24 hr test). The result indicate that my cortisol is elevated during the noon time.
What could possibly cause this? Could this be problem why my period disappeared and my weight went up?
7.40 AM 7.0 ng/ml normal range 3.7 - 9.5
11.40 AM 5.1 normal range 1.2 - 3.0
5.30 PM 1.1 normal range 0.6 - 1.9
9.30 PM 0.5 normal range 0.4 - 1.0
Anything eventful when you did th 11:40 sample?
Did you feel OK at the time and do you generally feel OK at mid-day?
When did you take your progesterone? Just once per day. Some women spike cortisol after applying transdermal progesterone [others not] and that might also happen with oral progesterone.
You are otherwise in good range and showing good profile of levels except from that one.
I had “weak” coffee around 10AM and had been fasting. I broke my fast at 12PM. So I am thinking the reason of cortisol spike could be either coffee or fasting.
I was reading a thyroid book last night which got into how many menstrual irregularities are a result of thyroid issues.
Hi KSSman
Going to check my thyroid in a week, will post update. Just a meantime can you recommend any good book to read about thyroid or hormones? I have read stop the thyroid madness and also few books about adrenal fatigue.
thanks
Sounds like your reading is quite good. I am reading STTM-II now, mostly contributions by doctors to lend some legitimacy to the eyes of other doctors and septics.
You asked about sources of iodine but never discussed you prior sources or what you are doing now.
Hi KSman and everyone,
I want to give some update about my hormonal issue. I haven’t had regular period for long long time. I’m 35 female. The last period I got was after I upped my thyroid dosage, which was in december; since then I haven’t had my period again. I got my blood work done last week and I was wondering if you can give me an opinion.
The problem - no period, swollen tender heavy breast, feel heavier, ehh. So flustruated.
My total testosteron is over the normal range.
Hemoglobin A1C 4.9 normal range <5.7
Prolactin 5.3 normal range 3.0- 30.0
TSH 0.01 normal range 0.4-4.5
T4 total 9.5 normal range 4.5- 12.0
T3 total 126 normal range 76-181
Estrogen total serum 738 normal range early follicular 70-400: late folicullar 100-900; luteal 70-700
Progesterone 21.2 normal range folicular <1.0 ; luteal 2.6-21.5 ; post menopausal <0.5
Testosterone total 72 normal 2-45
testosterone free 3.0 normal 0.1-6.4
Currently on 25 mcg cytomel, 125 mcg synthroid, 1000mg metformin.
Appreciate your input.
Why are you on metformin? Did not see this addressed at first
Have you gained any weight?
Did you actually scale back your training a bit, as recommended previously?