High T, FSH, SHBG, Low E2 No Libido. My Lab Results (pellets)

Just curious, why?

Anavar is highly anabolic, it’s big boy stuff. It carries a high risk of liver toxicity and other sides and has a completely different method of action than Danazol. Danazol is a weak androgen that will possibly lower you total T by blocking LH output, but give you higher free T because it binds to the SHBG in place of the test. Keep in mind, that action of binding to SHBG is considered a “Might could” effect - it works for some and might could work for you but no promises. Anavar could give you jaundice and numb hands but will certainly put 10 or so pounds on you almost overnight.

@hardartery

Got it. K, I’ll steer clear of that one, thanks.

Anavar has been shown to lower SHBG in low doses. There are a few threads on here in regards to this. I grabbed this link from one of them.

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That may be, but he’s never done anything. He hasn’t even started TRT, so that would really be going in the deep-end for a very off-label use.

I was unaware of his situation so you definitely have a point there.

Guess I’ll stick with the old trusty HCG and test Cyp then

Lets go back to the thread you started so you will have all of this in one place, since it is more about your situation rather than mine, since I have nothing to do with anavar, or hcg or any of the other items.

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That’s correct, benzos are known to lower pituitary hormones via sedation.

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My third and final trial of Proviron …

On May 19, 2019, I began experimenting with low dose Proviron. In previous experiments, I was taking 50mg twice per day (100mg/day), based on reading posts about its use.

My experiment was to see if arousal and spontaneous erections would increase.

I cut 25mg tablets into four - using one approximate 6mg dose per day. The tablets are supposedly in your system at full strength at 2 hours, with a half life of 10-12 hours.

There is NO medical study to justify my theory. However, in my 2 previous trials with Proviron, I felt horrible; much worse taking it than not.

I tried using with a high dose, why not try the opposite.

Guys here opined that I was crashing my Estadiol and SHBG, which is why arousal/erections became worse. I also wondered if Proviron was better for someone with “high-normal” SHBG who wasn’t already on something like Danazol.

But I haven’t given up on Proviron, because of it being touted as one of the best ways to increase arousal – although medical journals confirm that it does this best when the person taking it does not have any erection issues caused by medication or “other” reasons.

Proviron binds to SHBG and to Albumin. Contrary to what some have suggested, I don’t think I crashed my SHBG levels because of the insane natural level that I have; and Danazol has only brought them down to a “manageable” level - not a low level.

When you search for low dose proviron, you find 25mg as being “low dose”. NOT ONE article of any kind mentions dosages lower than that.

@tontongg thinks that 12.5mg is a dose that works for him. He is the only one that I can find that has mentioned dosages this low.

In theory, since there is a 12 hour half-life, I’m dropping back to a lower level and then trying to push it up again. I should be taking twice per day in order to keep the level of proviron stable in my blood.

I increased to 6mg twice per day; and then later increased from 6mg to 12.5mg twice per day.

Two and one-half weeks into the experiment, I stopped, as I begin to feel worse.

In all fairness, a proper test of Proviron would not include the Danazol that I am already taking – but I am not willing to stop the Danazol and reset the clock on how I feel.

But I am finished with testing Proviron at least as long as I am taking Danazol. I did not run any labs during this test.

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I always felt worse any time I’ve tried proviron as well. I suspect it is more estradiol related than anything else… I was really hoping for the crazy libido some people get but no luck for me either

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@traveling-man maybe I missed it before, but how come you are more concerned with your % Free Test versus what the labs are showing? It seems like your labs are consistently showing above range free testosterone. Isn’t the % free test something that’s done via a formula while the other reading is from your actual blood?

i.e. your Free Testosterone (direct) would show >50 in a range of 7.2 - 24.0 in earlier posts but you would still base your Free Test on an online calculator? Why is the online calculator more accurate in your opinion then the Free Test reading from your blood work?

I have insane SHBG levels which affects the true amount of Free T available. You can have boatloads of Free T in your blood, but none of it available to you because it is bound to and taken by SHBG and other items.

@traveling-man I thought the Free T in your blood is the T that’s free AFTER SHBG is bound to the rest of it? Other wise that would just be your Total T. Do you have any source where I can read more into this? My free T is very low when put through the calculator but my actual blood readings are in range. Would love to have something to show to my endo about that.

Traveling-man meant Total T, not Free T.

Sure but that still doesn’t answer my question as to why he’s using a calculator to calculate his Free T instead of going off of the reading from his blood tests? His blood tests show his Free T to be above the reference range at 50 >, yet he still thinks it’s low at times and uses the results from a calculator rather than the amount of free T in his actual blood.

I don’t understand it either, I’ve seen the same thing from labs in Germany.

@systemlord so I have blood tests from labcorp that show my Free T being at 13 in a range of 9-23. However, when I calculate my Free T using my SHBG, Albumin, and Total T, I get a Free T of about 7.1. So which measurement do I trust?

I found a more accurate Free T calculator, the other ones overestimate and were created before the testing methodology became standards. It doesn’t calculate Free T percentage, but what’s the point of using something that overestimates…

Free T closer to 10 ng/dL is approaching symptoms of low testosterone. https://tru-t.org/

The calculator is meant to give more of a median number, the direct test is a snapshot. There are also two different assay methods in use, and the one favoured in Germany produces a lower number. It is considered more accurate, like the difference in E2 tests between “sensitive” and regular. There’s a thread started by @vonko1988 I think that talks about it.