SHBG 29.8 (down from 85.6)
I have now completed two test cycles of Danazol and its effect on SHBG levels. Both times I have tested blood before Danazol, after use, after stopping use, and after starting again.
The results show that Danazol has reduced my SHBG levels substantially.
First Cycle: 101 to 33
Second Cycle: 85.6 to 29.8
This was based on 100mg of Danazol taken daily. The first cycle was 100mg taken ONCE per day; while the second cycle was 50mg taken TWICE per day.
I believe guys here have agreed that SHBG levels should be in the range of 15-20 to get the best results of Free T. That makes me wonder if an increased dose to 150mg per day will bring my SHBG levels down further.
Danazol is used off-label to reduce SHBG in men. However, there are dozens of studies confirming reduced SHBG levels in women with PCOS or endometriosis. In those studies, dosage was from 200-600mg per day over 9 months.