High Estradiol & Gynecomastia / Bottom Range T

Getting E2 too low can make you feel horrible!

More is not better, optimal is better. Get E2 labwork done and try to be near E2=22pg/ml.

I suggested 0.5mg a week, dosed twice a week, 0.25mg per dose.

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@KSman anastrozle worked for me my estradiol dropped to 42pg/ml (normal is 39.8) closed to normal range. M really happy with this results and also my testosterone also increased to 532.6 ng/dl ( 249-836).
Now how long should i continue anastrozle with this dose of 0.5 mg weekly ?
One more thing u suggest me for blood drainage previously. I couldn’t understand what is this and how to do that ?

You dose the AI for life. If the dose worked great, I’d continue on it, even if it was a mistaken dose. I wouldn’t change anything if you are feeling better and the bloodwork confirms it.

He was proposing you go and donate blood. Look for the red cross vampires, they are always happy to drain some excess blood.

Your E2=42 pg/ml can be taken to E2=22pg/ml by increasing dose:

new dose = old dose X current E2 / target E2
new dose = .5mg/week X 42/22 = 1.0mg/week

Lower E2 has increased T and that leads to more T–>E2, explaining why E2 has not dropped more.

Try the new dose and note changes.

Many feel horrible near E2=42, so you may have some strong benefits.