High E2 Symptoms, Confused and Fed Up

Pharma TRT
22

Update:

Labs Received today.

Red Blood Cells
Haemoglobin X 177 g/L (Range: 130 - 170)
Haematocrit X 0.505 L/L (Range: 0.38 - 0.5)
Red Cell Count X 6.03 x10^12/L (Range: 4.4 - 5.8)
MCV 83.7 fl (Range: 81 - 98)
MCH 29.3 pg (Range: 27 - 33)
MCHC X 351 g/L (Range: 300 - 350)
RDW 12 % (Range: 11.5 - 14.4)
White Blood Cells
White Cell Count 8.03 x10^9/L (Range: 3 - 10)
Neutrophils 4.92 x10^9/L (Range: 2 - 7.5)
Lymphocytes 2.28 x10^9/L (Range: 1.2 - 3.65)
Monocytes 0.64 x10^9/L (Range: 0.2 - 1)
Eosinophils 0.08 x10^9/L (Range: 0 - 0.4)
Basophils 0.08 x10^9/L (Range: 0 - 0.1)
Clotting Status
Platelet Count 281 x10^9/L (Range: 150 - 400)
MPV 9.9 fl (Range: 7 - 13)
Kidney Health
Creatinine 101 umol/L (Range: 59 - 104)
eGFR 80.13 ml/min/1.73m2 (Range: ? 60)
Liver Health
ALP 69 IU/L (Range: < 130)
ALT 44.9 IU/L (Range: < 50)
GGT 21 IU/L (Range: 10 - 71)
Proteins
Total Protein 73.4 g/L (Range: 60 - 80)
Albumin 42 g/L (Range: 35 - 50)
Globulin 31.4 g/L (Range: 19 - 35)
SHBG X 16.5 nmol/L (Range: 18.3 - 54.1)
Diabetes
HbA1c 35.08 mmol/mol (Range: 20 - 42)

Cholesterol Status
Total Cholesterol 2.84 mmol/L (Range: 0 - 5)
LDL Cholesterol 1.12 mmol/L (Range: < 3)
Non HDL Cholesterol 1.48 mmol/L (Range: < 4)
HDL Cholesterol 1.36 mmol/L (Range: > 1.1)
Total Cholesterol : HDL 2.09 ratio (Range: < 4)
Triglycerides 0.8 mmol/L (Range: < 1.7)
Muscle Health
Creatine Kinase 290 IU/L (Range: 39 - 308)
Iron Status
Ferritin 31.7 ug/L (Range: 30 - 400)
Thyroid Hormones
TSH 3.16 mIU/L (Range: 0.27 - 4.2)
Free T3 6.63 pmol/L (Range: 3.1 - 6.8)
Free Thyroxine 17.500 pmol/L (Range: 12 - 22)
Hormones
Hormone Phase Men Phase
FSH X <0.3 IU/L (Range: 1.5 - 12.4)
LH X <0.3 IU/L (Range: 1.7 - 8.6)
Estradiol X 227 pmol/L (Range: 41 - 159)
Testosterone X 32.5 nmol/L (Range: 8.64 - 29)
Free Testosterone - Calc. X 1.05 nmol/L (Range: 0.2 - 0.62)
Prolactin X 343 mU/L (Range: 86 - 324)

In Common Units

Total Testosterone - 936 ng/dL (Range 246 - 835)
Estradiol - 62 pg/ml (Range 11 - 43)

23

Labs received today, so right man previous labs were useless look at the difference!

24

I knew your levels were still too high, lower the dosage a little until you feel good, but this once weekly dosing isn’t likely to keep hormone levels very steady and will spike estrogen higher creating more aromatization in the process.

25

Have been doing EOD since Dec time, has made a difference. What dosage would you think to go down to, currently 50mg EOD.

Total Testosterone - 936 ng/dL (Range 246 - 835)
Estradiol - 62 pg/ml (Range 11 - 43)

i thought 936ng/dL for TT was not even too high? isnt up to 1200 - 1500 considered high end?

26

I would do daily, but if you must do an EOD protocol, I would do 45mg EOD -20mg.

Be prepared to feel better.

The numbers are a guidepost, symptoms will determine if levels are too high, if you feel fine that’s all that matters. You said changing to an EOD protocol made a difference, lower the dosage and keep going until you notice a difference again and stop once you feel optimal.

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27

Forget people telling you your dose is too high based on numbers because most guys I deal with have higher numbers than you with no symptoms. There is a possibility that these levels are too high for YOU and not due to clinical ranges.

Your total T calculates to 937ng/dL. Your free calculates to 30 ng/dL. Lots and lots of men doing great at these numbers. Some need more, some need less. We need to determine which side you’re on.

Considering the anxiety, I would suggest using a touch less. 50mg EOD works out to 175mg a week. Try bringing it down to 40mg EOD for a total of 140mg and report back if you are feeling better or worse after a few weeks. Then we will know for sure if you needed to go higher or lower.

Forget about the damn clinical ranges FFS. You need to know what is the best dose for YOU and not the best dose for other people.

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28

Are you overweight? I noticed a few readings I didnt like. Also you may have soon issues with iron, I would consider doing something there

I remember reading low iron ca cause anxiety.
Your test and estradiol look perfect on paper, but most important is how you feel

29

PERFECT ON PAPER the man says.

PERFECT ON PAPER.

Perfect for WHO???

Fuck my life.

Please someone do share the PERFECT NUMBER that applies to everyone so I can stop wasting my time helping people.

1 Like
30

Low iron isn’t the only thing that causes anxiety, just ask dbossa. Lol!

He did say perfect on paper, it’s no different than if he stated levels look optimal on paper. Your pain runs deep with the “perfect comment”. It’s understandable if people know your story.

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31

Stating perfect on paper when it comes to this stuff demonstrates zero understanding as to how it works.

Stating your numbers are ‘normal’ when it comes to this stuff demonstrates zero understanding as to how it works.

There is no ‘normal’ or ‘perfect’. Every person will require a different dose. You can go as far as saying what the majority is doing, as a vague indicator as to where you situate, but that’s it.

Picture yourself on a deserted island. You have no labs or blood work available. Only testosterone. What do you do? You try more or less until you feel better. I bet I could get anyone feeling better on a deserted island with no labs by simply using a bit of logic and common sense. As soon as you guys see numbers on paper you lose your shit and everything gets complicated.

32

Do what Danny Bossa said above and lower the dose just a little and don’t panic.

You have other issues with insomnia and then you have issues waking up. You have been doing TRT for 3 months. That’s nothing in terms of how long you have been on this.

Stop looking for answers in other solutions and simply change your dose as Danny said and give it some time. You might just need a little less. Sometimes more isn’t better for us. Some of us can take 300mg and need it. Others can take 150 and feel great. If they take 200 they feel tired and not as great.

Just take baby steps and I suggest that you stop looking at every symptom and correlating it to TRT. It very well could be something else like your brain stressing your body out.

I wouldn’t over complicate this with SHBG numbers and estrogen worries.

The basics of TRT are finding a dose that helps. Not oh my god my estrogen is causing issues.

33

Indeed. I can just imagine him screaming on the monitor :smiley:

34

Yet you can’t look away, can you Vonko. You watch every single one. Funny how that works.

35

What is your free t?