Pill cutter. I have no idea how to get it into an 8th. This people must have experience cutting “stuff” with razor blades.
I’ve crashed e2 with both Letro and Adex, and both sucked. I’d have to dive into the BB stuff with Adex, but take e2 low enough with either one and you’re in for a bad time.
You’ve got the right idea, starting low. I’d dose it EOD if I was doing QD injections since the HL is 48-50 hours. Keep everything very stable. Get labs after 3-4 weeks. The AI does work quickly, stopping conversion of e2 within hours
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Pill cutter for quarters, but that’s as far as I can get with them. I have tried to scrape 1/4 tab down with a knife but just ended up with dust. Better to have a lab compound .125mg tabs (Empower does)
No. That is not how human biology work.
No evidece for it.
High e2 make you store fat more like a woman so that is to be expected.
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No, fat will lead to higher E2 levels. Low E2 will lead to increased fat.
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You’re gonna hear it all. In my specific case, I run high E and Im lean. Keep thinking that E makes you like a woman and that’s where you run into misunderstanding the whole thing.
I’m growing tits… thats not the T is it?
One of the things that people lose site of is we are all physiologically different.
I’ve got high SHBG. I have to run T at the top of normal range to get any sort of resolution- this causes my e2 to also be about top of range (sometimes above).
SHBG binds tighter to T than E2… so I’ve got T and E2 at top of ranges… but if you look at free T to free E2 then I guess I’d be E2 dominant as a ratio.
A small amount of A.I may be appropriate for myself in this situation?
.25mg a week of Adex will not destroy you. Do it and assess the situation in 4-12 weeks. But its been mentioned before that Nolva is better for gyno concerns. Get it and follow the minimum dosage that is considered to be effective.
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Cheers fella.
Do they come in 1mg tabs usually?
Was considering exemestine also?
That’s exactly my thinking.
My SHBG is very high (way above range), so despite high TT and FT my guess is that if you look at the ratio of FT to Free E2 I would be E2 dominant because SHBG binds androgens more tightly.
I’m actually going to start testing Free E2 and Free DHT as well so I can compare apples to apples, instead of comparing FT to total E2 and total DHT.
I just started taking 1/32 of a mg of Anastrozole daily, which adds up to slightly less than 0.25mg/week.
Certain anti-aging clinics (not sure we can mention names here) sell 0.125mg tabs through compounding pharmacies; they’re designed to be splittable in half and I use a pill cutter ($6 on amazon) to cut them in half again.
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No such thing here in the UK unfortunately.
My physician is prescribing arimadex. He’s suggested a starting point of 1/4mg 3x weekly.
Seems a bit high as a starting point?
From everything I’ve read that sounds like a lot, especially for TRT dosages. Guys crash their E2 with less all the time.
Can you only get 1mg per tab in the UK? If so I don’t know that splitting pills in 1/8ths is really doable. Some people dissolve the Adex in Vodka and use a syringe to measure out microdoses.
For ex if you dissolve 5mg of Adex in 5ml of Vodka you’d have 1mg/ml of Adex/Vodka, so 20 units on a 100 units/ml insulin pin would be 0.2mg (just to be clear you wouldn’t be injecting it, you’d just squirt it in your mouth or something like that)
Yeah I’ve read about dosing it that way.
I’ll do a bit more reading about whats worked for people.
I have just moved to eod injections to try and see if I can avoid it though but I’m convinced its the free e2 thing we discussed due to high shng that is causing my issues.
Yeah I think that’s really what’s going on. I’m thinking of trying the compounded cream applied to the scrotum. The increase in DHT levels could create a better androgens to estrogens ratio despite the high SHBG, and DHT is also a natural E2 antagonist.
EOD injections is also a good idea. I think it would lower SHBG relative to ED injections since you’re injecting 2x the dose at once.
Just taken the plunge 1/4mg anastrozole down the hatch. Gonna do what the Dr suggested as he got my starting dose of T pretty spot on and do 1/4mg 3x per week. Will do bloods in 8 weeks!
androhard gel increased my DHT quite a bit. I ran between 29 and 39ng/dl for years before using it. 4 pumps 2x daily of androhard bumped that to 64 on two different tests. 3 pumps 2x daily put me at 58.
I’m not sure I’ve noticed anything signficant. That and regular progesterone cream might be why I haven’t had the normal E2 sides I would normally get at my current levels.
I do daily test cyp subq injections and daily Adex. I mix 3 x 1mg Adex tablets with 20ml vodka in a plastic bottle that has a measuring pipette built in to the lid and take 0.25ml orally as soon as I wake up. Couldn’t be easier. I mention the timing because a few years ago I went on holiday and started taking it with a large breakfast every morning. It stopped working, so since then I have always taken it on an empty stomach.
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Whats that work out dosage wise for the a.i? I’d have to get a calculator out to work that.
I’m considering breaking tabs into 6 and doing 1/6 mg per day for now