Control of Estradiol?

FT levels control FT–>E2, then levels are determined by liver clearance of E2.

T is dosed in mg’s. Do not understand 200IU.

Can be more specific if you post current labs with range and TRT protocol.

T subq absorbs slower delivering smoother T levels. Anastrozole is a competitive AI, competitive with T. So steady T levels are needed. Suggest T injections subq twice a week and take anastrozole at time of injections. Injecting 2 EOD would be better, but a bit of a burden.

Please see last paragraph re thyroid.

Please read the stickies found here: About the T Replacement Category - #2 by KSman

  • advice for new guys - need more info about you
  • things that damage your hormones
  • protocol for injections
  • finding a TRT doc

Evaluate your overall thyroid function by checking oral body temperatures as per the thyroid basics sticky. Thyroid hormone fT3 is what gets the job done and it regulates mitochondrial activity, the source of ATP which is the universal currency of cellular energy. This is part of the body’s temperature control loop. This can get messed up if you are iodine deficient. In many countries, you need to be using iodized salt. Other countries add iodine to dairy or bread.

KSman is simply a regular member on this site. Nothing more other than highly active.