haha no worries man, I appreciate it cuz I know some things but not everything. I suspect that the majority of people will use testosterone as the backbone of their cycle either way though.
Deca has been related to Penis GROWTH in teens. So answer is big no.
[quote]Vatic wrote:
Deca has been related to Penis GROWTH in teens. So answer is big no.[/quote]
And Arnold told Zack Braff to eat more carrots in order to get bigger…
-
Your penis is fully grown essentially when you are finished with puberty (and again, nobody should be doing steroids that young)
-
As you build muscle mass, your penis may LOOK smaller as it stays the same size, muscles grow bigger, penile tissue does not
[quote]BamaGuy1024 wrote:
-
Your penis is fully grown essentially when you are finished with puberty (and again, nobody should be doing steroids that young)
-
As you build muscle mass, your penis may LOOK smaller as it stays the same size, muscles grow bigger, penile tissue does not
[/quote]
You look like a bodybuilder from the turn of the 20th century…
DHT is critical for the development of the penis and testes. If one has a defect for no DHT or defective DHT receptors, a micro penis results. T is necessary, but not sufficient. Testosterone as gear will increase T and DHT so penis size will not be a problem. DHT derivative gear may tie up the DHT receptors, but might not lead to all of the needed gene expression support needed for normal sexual development.
But KSman - isnt that all academic unless you are under 16?
[quote]KSman wrote:
DHT is critical for the development of the penis and testes. If one has a defect for no DHT or defective DHT receptors, a micro penis results. T is necessary, but not sufficient. Testosterone as gear will increase T and DHT so penis size will not be a problem. DHT derivative gear may tie up the DHT receptors, but might not lead to all of the needed gene expression support needed for normal sexual development. [/quote]
Can you inform us of what a “DHT receptor” is? Or a “defective DHT receptor” ?
I’m sorry but this is not the case.
It is the case that DHT is more potent at the androgen receptor than testosterone itself, and where 5alpha-reductase deficiency exists, there is therefore much less activity of the androgen receptor for any given free testosterone level, and this results in micropenis.
But not that DHT (or anabolic steroids lacking a double bond in the 4-position) has different receptors than does T.
Bill - I know that when we first created synthetic Test’rone and begun researching it in depth for the following years, this was a common belief, but was it learnt that this was not the case on the discovery of the 5a-R enzyme/the creation of the 5a-R inhibitor or before that?
That is an interesting question on when it was first learned that the androgen receptor is activated by both testosterone and DHT, as well as the various synthetics.
Approximately speaking, this was learned in I think the early 70s, possibly a little later, but I am going from fairly generalized memory on that, not recollection of a specific journal article.
However, as to whether there was only one type of AR (within the same individual; not in reference to mutations) that was activated by both testosterone and DHT, I don’t think this was fully resolved till the late 80s or early 90s. In other words, it was known before then that any androgen receptor could be activated by either T or DHT, but it wasn’t known whether there might be differing subtypes. In fact, differing subtypes were expected.
I don’t know when 5-alpha reductase was discovered but it must have been pretty early on. Probably in the 40s, as a guess.
Finasteride was developed in the 80s, but there may well have been study of 5AR inhibitors prior to that, though I don’t know.
But yes, it’s as you say: in the development of synthetic anabolic steroids in the 50s and 60s, medicinal chemists did expect that “anabolic” and “androgenic” activity were mediated by differing receptors, and were aiming to achieve selectivity between these receptors.
The molecular biology tools were not available then to resolve the matter.
[quote]jomamma007 wrote:
I know they can stop your platelets from growing preventing one from reaching their full height but can they stunt penis growth? What else can they stunt besides height? Obviously im talking about if a person around the ages of 16-20 were to use them.[/quote]
You are confusing HGH with AAS. Growth hormone is the substance that may affect platelets. Never read or heard of a study indicating anabolic androgenic steroids do that. High blood pressure, acne and hair loss, but not platelet fusing.
I agree with other posts that penis growth after puberty is unlikely anyway, so unless you marry Alena Bobbit, your penis will stay the same size regardless of what you take.
[quote]jomamma007 wrote:
I know they can stop your platelets from growing preventing one from reaching their full height but can they stunt penis growth? What else can they stunt besides height? Obviously im talking about if a person around the ages of 16-20 were to use them.[/quote]
If you use them they will kill you. I also recommend you avoid driving, firearms and the internet.
However a 9mm or less is safe because as we all know, among the common semiautomatic calibers only a 45 has enough power to get the job done.
[quote]Bill Roberts wrote:
That is an interesting question on when it was first learned that the androgen receptor is activated by both testosterone and DHT, as well as the various synthetics.
Approximately speaking, this was learned in I think the early 70s, possibly a little later, but I am going from fairly generalized memory on that, not recollection of a specific journal article.
However, as to whether there was only one type of AR (within the same individual; not in reference to mutations) that was activated by both testosterone and DHT, I don’t think this was fully resolved till the late 80s or early 90s. In other words, it was known before then that any androgen receptor could be activated by either T or DHT, but it wasn’t known whether there might be differing subtypes. In fact, differing subtypes were expected.
I don’t know when 5-alpha reductase was discovered but it must have been pretty early on. Probably in the 40s, as a guess.
Finasteride was developed in the 80s, but there may well have been study of 5AR inhibitors prior to that, though I don’t know.
But yes, it’s as you say: in the development of synthetic anabolic steroids in the 50s and 60s, medicinal chemists did expect that “anabolic” and “androgenic” activity were mediated by differing receptors, and were aiming to achieve selectivity between these receptors.
The molecular biology tools were not available then to resolve the matter.[/quote]
Thanks.
For the benefit of those who are reading quietly soaking it all up - I am glad actually that you made the point of adding in “the androgen receptor is activated by both testosterone and DHT, as well as the various synthetics” as this is also not understood by a lot of posters (and i assume many more lurkers) who think that the mode of action differs for the synthetics or more accurately the non endogenous androgens.
I should add that the difference in effects are largely due to differences in (androgen) receptor binding - or how much activity there is at the AR, or (inversely) how much is then free to exert its (anabolic) effects elsewhere in the body, along with the timing, potency, enzyme interaction, protein binding, etc.
Thanks again Bill 
[quote]conorh wrote:
jomamma007 wrote:
I know they can stop your platelets from growing preventing one from reaching their full height but can they stunt penis growth? What else can they stunt besides height? Obviously im talking about if a person around the ages of 16-20 were to use them.
If you use them they will kill you. I also recommend you avoid driving, firearms and the internet.[/quote]
I am actually only 3’9" and don’t possess a penis any more. However i am PERFECTLY proportioned and can lift 1.5x my own bodyweight in the bench… so that’s about 135lbs…
Well, SOMETHING shriveled my penis it MUST be the steroids!!! At least that’s what I tell my wife, LOL.
Someone get get in touch with that grapefruit…