Its a dose dependent effect. See the study.
No, I am telling everybody who experiences side effects attributable to high dose.
Effect of T on erythrocytosis is dose dependent, see study. In man who are suscetable to this they have to adapt their dose or deal with the consequences. Thats why I wrote either donate OR lower the dose.
Again, for those who are susceptable (thats unfortunately the majority) low ferritin is not the problem (unless you develop eg restless legs syndrome), but only a symptom of higher rate of erythrocythosis. Whether high HCT values are really associated with higher rates of thrombosis, stroke and myocardial infarction or an innocent bystander is still a matter of debate.
Anyhow because of the precautionary principle most regulators and medical societies recommend to stop TRT or reduce dose upon development of polycythemia, HCT >54%
At his current dose he is heading toward this.
Just wondering is there a reason why you went for fumarete instead of bisglycinate?
Asking because bisglycinate has been shown to be absorbed two to four times better than other forms.
By the way i have access only to capsule form of L-Lysine(solgar 500mg). Not sure if it will make that much of a differenceā¦
@johann77 Thank you for the info once again.
I have couple of questions , so i can clear my mind.
You are saying i am heading towards polycythemia purely based on my current HCT , HB , RBC levels right? I am now at 6th week with new TRT protocol and you think these numbers will be higher if i continue with my current T dose. Is there no chance that my levels stay the same if i keep my current T dose?
How so? Shouldnāt i try to increase it?
Natureās Way ? Nature Made ? Natureās Bounty ? I can go on with all the Nature brandsā¦ There are like a billion of them 
Your HCT increased from 45.5 to 49.7 within 6 weeks, so yes I think you will develop high HCT.
But as mentioned you can also stay on your dose and just check again in a month and then make an informed decision (being either blood letting or dose reduction if it comes back high).
In case you run high in HCT and decide to stay on your dose and do frequent blood donations then yes supplement with iron (I prefer iron amino acid chelates as they donāt mess up my stomach). You just want to make sure not to completely deplete your iron stores.
If you decide to lower your dose to a point where you are long term fine with regards to HCT and donāt need blood donations than I would not do anything. It will recover on its own if you eat a balanced diet.
Got it. If HCT stays within these levels (49.7) i guess i will be good and only will have to get the ferritin up if i can.
Is HCT the most important marker compared to HB and RBC?
Dude donāt worry about something that isnāt a problem yet. Everyoneās HCT rises on TRT. How much more if any will yours rise? Who knows. A majority of peopleās HCT doesnāt get into crazy high numbers. Plus yours has room to go up. Thatās why I said he tells everyone to lower their dose. How about lower it when you need to?
I was recommended the fumarate because it has less effect on your stomach and many people have had success with that exact iron/brand.
Once I over supplemented potassium and my body in an attempt to protect the me from harm drumped potassium into the urine and stool. GI bleed can be a reason for low ferritin, this will even cause low testosterone.
400 or 1200mg of potassium got me the same levels.
Youāve had to quit TRT just to increase your ferritin right?
How was your HCT and RBC when you had low ferritin?
Yes , i will regularly check with labs to see where itās going , then lower my dose if i have to.
Ok my new RT3 result just came in. There is a considerable difference with my result from last blood work.
30th of August - Reverse T3 204.5 pg/mL
28th of September - Reverse T3 160 pg/mL
Also 6th of May - Reverse T3 132.2 pg/mL
I canāt decide on my thyroid medication with these resultsā¦ Is 160 still a high number for RT3? Should i still consider T3 only med?
I also have very low T4. ( 5.73 ug/dL 5.13 - 14.1 ug/dL). Does that mean if iād have a moderate amount of T4 levels then would my RT3 be crazy high? Because my RT3 is high with only a little T4 available.
I have yet unknown medical problems that keep presenting themselves and testosterone elevation is associated with these symptoms severity. I stopped TRT and when the cypionate was out of my system, for one week no symptoms, then my HPTA rebooted and felt amazing for one day and then symptoms began again.
My doctor and I both believe my diabetes lowered my testosterone, so my doctor put me on diabetes medicine and now am experiencing the same symptoms as when on TRT, only using diabetes medicine.
The day after starting this diabetes medicine, I had incredible energy, muscles firmed up then woke up the following day and returned to these symptoms. Whenever my blood gets thicker (46<->50% HCT), I have problems.
Itās clear to me I donāt need TRT, I need to treat the diabetes and my testosterone will go back up, but I have to find out what is causing these other symptoms.
Do you have free T3 numbers to go with those?
My average FT3 is 2.85 pg/ml (2.04-4.40 pg/mL) for those 3 blood tests.
I would try to get fT3 up to 4.0 and I would take a bioidentical T3/T4 combo.
You mean with my last two RT3 levels you would go T3/T4 combo huh?
My only option is Thyroid-S from Thailand for that. I guess it will do.
Yes, hope it helps.