Better to space out?

I’m going to be using 500mg of Sustanon a week and was wondering if it is better to inject all 500 at once or to do 2 separate shots in the week and if so, how many days after the 1st shot of 250mg should I wait to do the 2nd?

It’s best to make the first injection of the cycle the full weekly dose on the same day, but then after that, half the weekly dose twice per week, for example, on Mondays and Fridays.