Everybody makes mistakes. Live and learn.
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Yes but only if you give it to your research mouse.
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Understood, thanks so much!!
What type of dosage might be best?
@physioLojik Bit of a more obscure question but hope you can help.
Can you explain if there is any connection between a high prolactin level and the inability of a females ovary to utilise hcg for egg maturation in ivf?
We have been told that although my wife shows no symptoms of polycystic ovary her response to the ivf drugs suggests that she is insulin resistant and her ovary are polycystic like. My wife has a prolactinoma and I canāt help but think itās connected via down regulation of receptors.
I understand it may not be your area of expertise but Iām desperate for some insight. I can explain the question further and add some context if required.
Thanks
Ansoltuely can be causing her issues. How does she handle insulin and glucose? Acne? @kd13
@physioLojik No acne at all, no excessive hair growth, no signs of excess male androgens, low bmi really slim with little body fat. Normal amh for her age whereas polycystic is normally High. Never had a glucose intolerance test but the clinic said even passing a glucose test wouldnāt prove or disprove a high level of insulin within the ovary so not much use in testing. She is tired a fair bit but works a stressful job and we have a toddler from an ivf cycle so may just be that . She does have a low sex drive which I believe could be related but really no real obvious symptoms.
I have found a study linking high prolactin with insulin resistance in lean woman.
They are planning on treating her with metformin, getting prolactin lower and changing ivf protocol and trigger.
she seems to over respond to the fsh causing high number of follicles but then at retrieval a high number of immature eggs. Itās as if something is blocking the hcg and hindering maturation.
After 4 fresh cycles and only one successful embryo out of over 100 eggs itās getting very frustrating. Especially since we are doing ivf due to my obstructive azoospermia and not due to my wifeās issues.
You could start at 10 mg / day and up to 20 if needed
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Absolutely
@unreal24278 hahaha too bad spelling isnāt actually grammarā¦spelling is under the umbrella of writing. So I suppose I need the writing police.
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Butā¦ butbutbutā¦ There isnāt a meme for that
Waitā¦ Found a meme for it
Yeeeeeettttt
I had no idea they made a music video for thisā¦ Itās now my favorite video of all time, Itās ansoltuely amazing
Great. Iāll try 10mgs at first. Iāll keep you guys posted on how it goes. Thank you for the quick responses and knowledgeable answers. You have no idea how much it helps! Thanks again.
-Will
@studhammer, I think he is talking about using nolva for pct/restart not cycle support. Shouldnāt he run something more like 40/20/20?
Yes you are correct @alldayeveryday I need a PCT for the next 3 weeks to try and revamp my test ASAP before Navy Bootcamp
I would run nolva 40/20/20
Sorry, Iām not a PCT guy. Listen to @alldayeveryday
No worries @studhammer , you guys have set me on the right track, and for that I cannot thank you enough :). So to be clear @alldayeveryday by 40/20/20 you mean 40mgs week 1 and 20mgs both week 2 and 3?
Correct.
How quickly can thyroid hormones change? In a matter of hours, days, weeks?
Example: If a person got stung by a bunch of fire ants last night, could it effect thyroid hormones by morning?
Asking for a friendš¤£
Are you ok?