As promised earlier, I’ll add in my experience, which goes against the general principle here. Of course, this is just my single case, which is far from the depth some people have in this topic, so I’ll not jump at conclusions, just share what I experienced.
So, in line with what I read here, I did not jump on heavy AI use when I started my first blast of 400 mg T/week. I still took just a bit of Adex, as from my earlier TRT experience I knew I’m not the least aromatizer guy in the world.
Then I had symptoms which were almost inconclusive to whether my E2 was high or low. When my nipples became tender right before my lab was due, I guessed it’d be high, but as my issues were much more mental and cognitive (fatigue, brain fog, low mood, etc.) than breast related (no swelling AT ALL, no lumps, nothing, just some itch and mild tenderness) I was really surprised to find out my E2 was at 80 pg/ml.
So this relates back to sg I raised here a while ago. What’s the point of fighting E2 with a SERM and not an AI when the SERM does NOT help with the symptoms that come earlier than the ones the SERM helps. That is, SERMs don’t seem to help with E2 messing with my brain, water retention, etc. They do one thing, block E2 from breast tissue receptors. Now if at 80 my breasts were almost fully intact, but the mental symptoms were absolutely prevalent (and were amazingly relieved once I upped my AI), I wonder how Tamoxifen could’ve helped me at all had I been using that.
I hope my dilemma makes sense.