Anyone Use Progesterone Directly With TRT? Maybe For Libido?

Interesting read is how progesterone and estrogen actually might work together to assist breast cancer development in women, but again, that’s at different hormone levels than in men. Progesterone does, however, reduce estrogen receptors, not free estrogen, which supposedly is what helps cancer form.

Regarding the pituitary gland, one article points out that progesterone does in fact aid the pituitary gland in producing lutenizing hormone, but again, this study was in women. However, if progesterone does reduce estrogen receptors in the pituitary gland of men, this could possibly increase lutenizing hormone production.

And sre we saying pregnenalone converts to progesterone?

Or have I got that wrong?

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Always like to get your take on this @highpull Highpull, you give your clients sensible protocals in my opinion.

Have you ever experimented with Pregnenalone? I’m interested in the memory aspect of it.

I’m not sure if its lack of sleep or a few years on TRT but my recall of nouns is definitely worse at the minute- sound like me nan “the whatdyamacallit”, etc… takes a few seconds to locate the name in my head sometimes with things.

But my sleeps been absolutely terrible recently so could easily be that!

No. I think it works as a precursor to the other hormones. Lab tests are not reliable, so it is difficult to test. We would give DHEA and testosterone for those symptoms. However, I do not see any harm in trying it.

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Roughly a week of taking progesterone, and today I’m feeling almost like chills, but not in the usual sense like in your core, but more in my limbs, certain surfaces that feel cold when normally I’m boiling hot on tren, etc. Also have been feeling almost numb in certain places. Also, virtually all estrogenic “puff” is gone from my face. I like that, but not sure of other things. There’s a lot of mixed data about the halflife of progesterone, some saying that it’s very short. However, it’s being said that natural vitamin E oil can stay in the system for quite some time, and I imagine that if progesterone is dissolved in it, the progesterone might linger, too. The longest halflife I’ve seen for progesterone is 20 hours, and at that rate, if taken daily, it could definitely build up. I was taking 6mg. Dropped to 3, and now I’m thinking of trying every other day. Sex drive is definitely up even if I do have some emotional trauma regarding past relationships, etc. What others have said here rang true and strong with me. I’m not one to get turned on simply by physical attraction anymore. I need a connection and trust. Also, regarding sex drive, etc., I have noticed testicular size to be fuller. Tren and sdrol really shrunk things down before. I stopped sdrol on Saturday. I’m hoping that the progesterone doesn’t ruin gains, but with possibly reduced estrogen receptors, it would only be natural that some size is lost due to reduced bloat. I’m also reading that it can lower blood pressure, which would be logical. . Also, sleep is quite nice these last few days.

People are turning their heads, saying, “Goddamn, you’re getting cut! You look good!” In the little time I’ve been using progesterone, my face and body have leaned out a ton. Great energy levels in the day. Great sleep at night. The one page I found that said men produce from maybe 5 to 15 mg naturally is b.s. They’re also saying that progesterone increases estrogen, but it actually reduces estrogen receptors and estrogenic effects. Most other data says men produce up to 0.75mg per day, so my 3 to 6 mg might be overkill, but it’s nowhere near the supposed sex change doses, and many studies say that there’s little proof that progesterone can even define sex because different studies contradict eachother on whether or not it competes for androgen receptors, and only at high doses.
To further my quest to make myself a guinea pig, I’ve ramped my tren up to 800mg a week, which might also be aiding in my cutting, but I was taking 340 before taking progesterone, and the leaning only started after the progesterone. First time I tried tren at 200mg a week, I was a mess. Rapid heartbeat, massive sweat, warm chest, rage, insomnia. None of that now. I sleep like a baby. I’m calm, happy, slow heartrate, peaceful. I really wonder if progesterone is the missing key, that gets messed up with tren and deca. I love this cycle so much that I want to do it again and again, but I’m curious to try a deca cycle with progesterone in the future. I’ll also add that I’m gonna skip the superdrol from now on. Took it at the begining of this cycle. Killed my appetite even on eq. As things are now, my appetite and energy levels are great.

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Hey, I’m dealing problems with tren.
I couldn’t deadlift or squat when i started tren-a, proviron, low test.

Back then I was powerlifting for some years, and taking test anadrol for 1 year tho, no joint issues whatsoever.

After 1 year for cant squatting and deadlifting. I bought estradiol valerate. I can deadlift now, but my knees are still trash.

I’m thinking anti-estrogenic effects of 19nors but I’m not sure about it.

One person said that trestolone does it via activating Androgen Receptor, so taking anti-progestin doesn’t solve the problem, anti-androgen does.
Also he says, anadrol weakly binding androgen receptor and releases tren, that reduces tren’s side effects.

I took 80mg e2 valerate intramuscularly, and e2 showed up 2565pg/ml but i still felt like i have low e2.

That tren fucked my biology up, but there must be some way to use it, and solve the problem.

Do you know anything about it?

@Robroy also you bro. You tried e2 val but I think you didn’t see something like this before.

Right now I’m just taking tren ace 40mg/day, e2 val 8mg/day.

Have you considered quitting the drugs that are causing you the problem? I used to tell my father that it hurts when I touch my “boo boo”. His age old advice was always… “don’t touch it”.

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Dunno man I suggest you stop everything but testosterone and MAYBE some e2 to balance things up (if needed) for a few months, then see what happends and re-assess from there.

Just do 300 test or sum, chill for a while and give ur body a damn rest already.

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Any more update? How’s the progesterone going?

Also what time of day are you taking it?

Still taking it. 3mg drop in vitamin e oil when I wake up. I should get some bloodwork to see where that’s putting me. Some say that it’s poorly absorbed orally, but at least one doctor said that it works quite well in e oil, and doesn’t get broken down by the liver right away. He did blood work and noted increase in levels and gradual decrease throughout the day. He said that powders and other oils do not produce the same results.

Sleep is great. I’m alert during the day. I’ve phased out the tren and other things and am moving to trt dosed for cruising. Just had hernia surgery, so no gym for 6 weeks, so I may as well cruise and continue the cruise into January or later. I questioned whether I should stay on cycle if I’m not working out, but others think that I’ll maintain muscle at trt doses.

Men supposedly naturally produce 0.75mg a day. I took up to 6 or 9 mg a day, and liked how I felt. My face leaned out. However, I’ve read that progesterone also dehydrates, and I found that my muscles got smaller. Reducing the dose got everything fuller again. I also felt passive at higher doses, and while I like to have a peaceful mood (especially on tren), I like to have a little edge, which is back now. I’ve mentioned either here or in another thread that my beard has turned from red to very dark brown. I’m assuming that that’s from the progesterone and not tren. I’ve taken tren before, but at lower doses.

This works so well for my sleep and mood that I’m going to keep with it unless issues come up.

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Are you taking an OTC product? My Dr gave me injectable - picking it up tomorrow actually.
My pregnenolone labs were 94ng/dl but this is supplemented by 50mg daily in the AM.
Progesterone levels came back as <0.5ng/ml with the reference range being <1.4ng/ml

Hoping this will help with libido I’ve been having a hell of a time finding it. When I started taking pregnenolone that helped a bit - but I increased my test dose from 100mg/wk to 140mg/wk and started an anavar cycle too and since then its just been completely gone

Decreased libido is common on Anavar. I wouldn’t chase it until you stop taking the Var.

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I’m taking an OTC product made by Forefront Health. I’m surprised that you’re being given 50mg a day. Men naturally produce 0.75mg a day. When you use higher doses, you get into the debatable androgen blocking range. That is, some studies show that much higher doses of progesterone compete with androgens for androgen receptors, and thus can feminize, while other studies show this not to be the case.

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Pregnenolone I’m taking an OTC 50mg daily.

The Progesterone I’m going to try 1mg/day and adjust up or down depending how I feel.

Also that was a good point brought up about the var - I might end up waiting until after I’m done with that

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interested as i seen progestrone may help my too hi estrodiol. i only use 0.06 test weekly + been on it since 2001, a little more when younger but age 75YO usually increases estrodiol as does high doses of test, just a regular guy trying to stay healthy, no real issues but thyroid was hi + armour is dropping it!