Advice for PCT? (Post Accutane Syndrome)

Thanks. Well, it is hard to say that it is actually working yet. There isn’t any noticable changes that i can distinguish it from the placebo effect. That’s why i considered the 10mg.

Also im working hard in gym and staying away from stress, abstaining from masturbation etc. That could also play a role. Maybe 10mg would be better idk?

How hard?

Oh lol, like not overwhelmingly hard. Im just a newbie but im really putting the effort. It clears my head and i gained 5 kilos.

Ok, just don’t overtrain. Newbs often fall into the trap of doing too much work instead of focusing on the essentials. Training too hard can wreck your sexual wellbeing.

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Just for the record, im increasing my dose up to 10mg eod today, since i don’t feel anything.
And planning to do a hormone test at the 5th week.

One little question, if PAS damaged my penile development at the age of 16, is there a chance that my penis will continue to grow to its genetical potential once i recover regardless of my current age?

I highly doubt your penis will grow but I don’t count it out.

I gave you advice on what you should do with your “What if?”s. Throw them out the window.

If you are feeling well and you got no physical problems, then you succeeded. There’s nothing to be gained from having these lofty expections about “unlocking potential”. If it happens good, of it doesn’t happen good.

Your objectives are: Do I feel generally good?
and Am I physically fine?
That’s enough.

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Good. Keep us updated!

Thanks, yes im trying to work on that mental issue. But it is very hard, accepting the reality and possibilities. Maybe my penis did grow on the inside (?) but i couldn’t notice it due to bad PAS erections, or maybe it s ready to express its potential and just needs the proper hormones.

Why is that? You seem to have a good knowledge on how genes and body work. Can you explain to me a little?
I thought we see penis growth on T deficient patients or transgenders, later in life. Can i think about my genetical potential as ‘‘suspended’’ due to PAS? So that when i recover, the genetic code of myself can express itself again and my penis can grow more on girth? Like a small second puberty. (Usually length stops around 16 i guess but girth continues till 18-19.)

Thanks. I wonder how these things work.

That is the point I can’t answer. Herein lies your assumption that doesn’t have to be true. If it’s not true, then there’s no genetic potential to be unlocked. I don’t see evidence of suspended genetic potential. You said you went through puberty. I don’t know.

You can try reaching replacement doses of T, try replacement doses of T and try supraphysiological doses and see what happens.
Why do you need your penis to grow? I mean yes it would be a nice side effect for most guys besides Mandingo, but do you NEED it?

I also dont really know what all your symptoms you need resolved and your expectations are. Can you make a list of

  1. What you need your therapy to do
  2. What you want your therapy to do
  3. What your current symptoms of your condition are
  4. Which parts of your bodily development you attribute to PAS and why
  5. Whats plaguing you mentally

Maybe I can see clearer then and better help you.

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I will reply to your comment, thanks for the summarize. :slight_smile:

For now, i just wanted to ask that should i increase my dose to 20mg eod? My pills are 10mg and i take them before bed.

So far doing good, i noticed slightly better erections and my testicles seem bigger. But no other symptomatic relief, semen volume is still low. I checked today, otherwise im on NoFap. This is still early to expect anything though, i have read people heal after the cycle. One guy with PFS experienced the same.

You can do that or go to 10 mg every day. I think it will work at 10 every day so I’d rather do that. Not a big difference, but also more convenient. I would maximally go to 10 every day if you plan to stay on it. No sides is very good. You can go to 20 if you just want to do a few weeks and take the higher risk for hopefully higher reward.

Good you’re getting some data

Yes. The rationale is that after the cycle your body settles at a new set point (or rather old set point) and the time to get there is accelerated by the SERM. During taking the SERM people often have negative sides which is why they feel better after it.

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Thanks, well yes i can switch to 10mg everyday. Or 20mg eod. :thinking: Now im kinda undecided.
20mg eod seems promising, but 10mg ed also seems good. Not much difference maybe in the end, i will try to find some studies about this.

The only difference is, your levels are more stable on 10 mg every day. It’s not a big difference though, as the half life is pretty long.

I am of the opinion that it’s better to dose more frequently.

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1- To fix my PAS and even recover, catch up the loss (If it happened) of bodily development due to it.

2- Same^

3- Well… Loss of penis size, almost no pleasure on orgasms, libido loss, morning wood loss, erection quality loss, low- odourless watery semen, very little sensation while urinating or holding the pee, numb PC muscles, testicle size loss.

4- Maybe my jawline, im not sure, i will never be, this hurts the most mentally. I will never know! My father has a slightly better jawline, i can see the bone on the jaw when i look to other people from sideways. But mine looks like as if it is clothed with fat tissue. Can’t see the bone. However, when i “mew” i get a very good jawline and sharp visible bone.

5- I think everything i said and experienced. But when i recover im also sure that i would be the toughest person on earth. Nothing can make me unhappy in life again, except goind blind or losing an arm or something… This disease is pure mental torture, even more for a guy with obsessive nature like me. Everyday of my life, i think some malevolent god played with me, it is like, the worst possible thing that can happen to me, happened. This disease is so rare, and it found me amongst million of people. I had a great, big penis with great libido and very good looking face. This must be a joke or a nightmare.

  • I have talked with a PAS case, just like me, he also took it when he was 16, full course, he even got diagnosed hypogonadal, he says he is almost asexual now :frowning: yet, he has a prominent brow ridge, good jawline and nice beard. So maybe, the issue is tissue spesific or more complex then we think, and my development didn’t affected ?
    Do you personally think this slight damage (i only had lowered semen on first 2 years.) could affected my bone development? If so, i really really wonder, can i express my genetic potential after recovery regardless of my current age?

I could only find this study, it states that the some of the delayed pubertal subjects age goes up to 16 year old.

So like, these guys had almost 5 years of developmental damage- genetical halting, but with TRT their mandible (lower jaw) bone made a catch-up growth to their peers. We also know that small bone remodelling is constant. But im not sure, because age of 16 is a very good age for development, im not sure if that same catch-up growth possibility applies to me since im 22 now :frowning: Are these changes all hormonal regardless of biological age? I wish they were. But i don’t think it is, since age also changes a lot of mechanism and cells in body.

At least PAS is not directly related to permanent Growth Hormone deficiency or GH receptor deficiency (?), but again, we will never know i guess. But im sure my issue is androgenic.

PS: Also found this and one more study stating “rapid pubertal development” with similar positive results, but the texts were not free so i couldn’t see any additional data rather than this:
"“In five boys with delayed puberty, tamoxifen treatment appeared to activate the pituitary-gonadal axis and pubertal development.”

1 and 2 is not the same.

This would be a WANT not a NEED. I hoped you would separate the symptoms you need to fix from those things that you’re just hoping they change.

This is interesting. Penis size is subjective. It could be that your erections are not as solid, that’s why it looks smaller. I did not hear of penises getting smaller before. I think it’s difficult to judge if it’s not fully hard. Did you measure?

These are the symptoms you need to get fixed. The rest is not essential (like having sensation during peeing).

If it’s only your jawline, I’ll give you the same advice I gave you above: get it out of your head. If this changes while you are treating your condition you’ll not notice it until it really changes a lot because this is something that would take a lot of time. If it doesn’t change then you live with the jaw you got and it won’t hurt you. It really won’t. So either way you don’t profit from being stubborn about this. Forget it and if it happens, it happens. It could also be that your body fat is too high. An extreme increase in leanness in the face, leading to a manlier look typically happens at under 11%. Though I wouldn’t diet hard in your situation, as caloric deficits make sexual function worse (at least if too large or too long).

You must become this person. Not only after you recover but through training yourself to ignore thoughts that are unreasonable (like “Some God played with my jaw line”) and only taking seriously rational thought. Practice stoicism, practice exercises that depressed people get, like thought-stop. It will not only help you deal with your mind until your bodily symptoms resolve but it will also power you through every bad situation in life. People flock to a person that’s strong. Become that person.

What does that mean? Your semen is normal now? That contradicts one of your symptoms from above

Well it could be.

That’s my thought on that. I can’t speak on this more than I have. It’s generally seen in men running AAS that they get some male characteristics increased like body hair growth. Women change look-wise partly into men on AAS, so I wouldn’t count out that you could see the changes you hope for.

How’s your tamoxifen treatment going? Can you get bloods?

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Just a quick respond, i gave bloods few days ago. But the results will show up in January 1.

So im on the 7th week on the protocol and thinking to end it next week. But should i? Maybe i need to use it more? Maybe 20mg? Or see the bloods first?

I don’t feel any changes. It’s like im taking placebo pills. But i guess this is normal, i hope something will happen when i quit.

You stay on your dosing schedule until you get bloods. They will tell us more.

I had some mental side effects on Tamox. I could definitely feel it. I guess another testament to how different we all are.

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Luckily i got the first part of my results now, i am kinda concerned because results are weird and makes no sense:

  • LH= 3.62 IU/L 1.7- 8.6
  • FSH= 1.82 IU/L 1.5- 12.4
  • Total Testosterone= 6,38 ng/ml (638 ngdl) 2,49- 8,36 Highest number in my life i guess.
  • Estradiol 66.28 pg/ml 11.3- 43.2 Doubled!
  • Prolactin 21.34 ng/ml 4.04- 15.2
  • Cortisol (morning)= 26 ug/dL 6,02- 18,4
  • Free PSA= 0,438 ng/ml 0.26- 4.14
  • TSH 2,83 uIU/ml 0.27- 4.2

High E2, Prolactin, Cortisol and unchanged LH? How on earth Tamoxifen couldn’t change my LH levels? My TT rised up from 490 (last test) to 638, but my LH is actually lower than before?

I have no idea how can i proceed from here? Should i stop Tamoxifen as i suppose to next week and wait for a miracle to get cured somehow?

I don’t want to mess with dopamine pre-cursors for high Prolactin or AI’s for my E2. I also at least expected 700 levels of T, why it is still on the 600’s…

If nothing changes when i quit Tamoxifen, im going to start low dose, long term HCG monotheraphy with (Experimenting with GH levels, i don’t give a damn anymore.) Genotropin+ MK-677. They are too are ready to go, JoeKool on Raypeatforum reported full recovery with HCG for his PFS.

Any free T or SHBG readings?

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They will probably available in new year. Im waiting. But this is strange, how it is possible that my LH actually less than before (4.0) but my T levels increased… I guess T production can be stimulated without LH then…